Informative indices of physical and functional state of young men during the process of adaptation to learning

The article presents the results of clinical and instrumental examination of adolescents and young men of military age with bradyarrhythmia. The study involved 2067 people (mean age19,7 ± 2,7 years), subject to conscription (from 17 to 27 years) and potential conscripts (16-year-olds). According to the results of the screening ECG, bradyarrhythmia (sinus bradycardia, sinus bradyarrhythmia, rhythm and conduction disorders) was diagnosed in 630 adolescents and young men of military age. We studied the functional status of the autonomic nervous system on the device “Cardiometry-MT” (Russia). The functional state of the autonomic nervous system was studied on the basis of cardiointervalography and correlation rhythmography. Evaluation of the functional state of the autonomic nervous system was carried out according to three parameters: the type of vegetative regulation of the heart rhythm (normotonic, vagotonic, sympathicotonic); reactivity of the sympathetic and parasympathetic parts of the autonomic nervous system (normal reactivity, hyperreactivity, low reactivity, and paradoxical reactions); nature of vegetative maintenance of cardiac activity (normal vegetative maintenance of cardiac activity, vegetative maintenance with adaptation, vegetative maintenance with disadaptation). According to the results of respiratory samples from 81,9% of adolescents and young men of military age with bradyarrhythmia diagnosed neurocirculatory asthenia, of whom 63,6% – light, while 18,3% – severe degree. With a mild form of neurocirculatory asthenia, compensatory mechanisms are connected, so vegetative homeostasis is not generally disturbed and the heart rhythm responds adequately to the effect of physiological stimuli. Severe form of neurocirculatory asthenia is characte rized by disadaptation of vegetative maintenance of cardiac activity. Such patients need regular follow-up because they are at risk for developing cardiovascular diseases.

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The Effect of Female Pheromone on the Functional State of Young Men

Acta biomedica scientifica ◽

10.29413/abs.2019-4.1.8 ◽

2019 ◽

Vol 4 (1) ◽

pp. 50-58

Author(s):

Nadezhda A. Litvinova ◽

Alena V. Bedareva ◽

Ksenia Yu. Zubrikova

Keyword(s):

Immune System ◽

Functional State ◽

Young Men ◽

Allergic Diseases ◽

Whole Body ◽

Synthetic Analogue ◽

Upper Respiratory Tract ◽

Male Mice ◽

Female Pheromone ◽

Olfactory Testing

Introduction.Modern studies show that the presentation of smell of female mice before male mice infection with the influenza virus activates non-specific immune response which protects male mice from infection of the upper respiratory tract and reducing their mortality. However the researches have not studied the adaptive effect of female sexual pheromone on men.The aimof this work was to study the effect of odor of synthetic analogue of natural female pheromone (Osmopherine) on the functional state of young men often suffering from acute respiratory infections (ARI) and allergic diseases.Materials and methods.We studied four-week effect of Osmopherine on the psycho-emotional state, the concentration of hormones (testosterone, cortisol) and immunoglobulins (sIgA, total IgG), the percentage of leukocytes in the blood and the individual smell of young men, who have ARI more than 4 times a year or an allergic disease. The study involved 117 boys aged 19–23 years. Olfactory testing of individual odor samples of young men was carried out by young women (n = 32) aged 18–22 years.Results.It was found that female pheromone has a positive effect on the functional state of men with different immune systems. However its effect is caused by the pathogenesis of the disease. Application of Osmopherine in men with reduced immunity causes an increased activity, improved mood, reduced anxiety and stabilized testosterone level. Men with allergic diseases did not have the same effect. A significant 2 times decrease in the content of eosinophils was found, which indirectly indicates the decrease in the activity of the delayed phase of allergic reactions of immediate type.Conclusion.The immune system functions according to its internal laws and programs. However its activity for the benefit of the whole body is integrated and regulated by the nervous and endocrine systems. Therefore modulating effect on the functioning of the immune system can be mediated through the presentation of pheromones.

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