Dual Detection Platform with Refractive Index and SERS Sensing Based on Colloidal Gold Functionalized Porous Silicon Substrates

2011 ◽  
Vol 1301 ◽  
Author(s):  
Yang Jiao ◽  
Dmitry S. Koktysh ◽  
Sharon M. Weiss
Keyword(s):  
Porous Silicon ◽  
Colloidal Gold ◽  
Infrared Region ◽  
Silicon Substrates ◽  
Molecular Fingerprinting ◽  
Molecular Binding ◽  
Sensing Platform ◽  
Surface Enhanced Raman ◽  
Dual Detection ◽  
Enhanced Raman Scattering

ABSTRACTWe demonstrate a dual-mode sensing platform based on porous silicon (PSi) substrates coated with colloidal gold (Au) nanoparticles (NPs). This Au-PSi composite structure supports both molecular fingerprinting via surface enhanced Raman scattering (SERS) and quantification of molecular binding via reflectance measurements. Reflectance shifts of 7-10 nm in the infrared region were observed in the case of adsorbing benzenethiol or antioxidant glutathione molecules on the surface of Au NPs. Subsequent SERS measurements showed unique identification for both molecules and provided a < 1 μM and < 1 mM detection resolution for benzenethiol and glutathione, respectively.

Phospholipid detection by surface-enhanced Raman scattering using silvered porous silicon substrates

2017 ◽  
Vol 214 (8) ◽  
pp. 1600915 ◽  
Author(s):  
Grigory Arzumanyan ◽  
Nelya Doroshkevich ◽  
Kahramon Mamatkulov ◽  
Sergej Shashkov ◽  
Kseniya Girel ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Silicon Substrates ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

scholarly journals Gold Nanofilm-Coated Porous Silicon as Surface-Enhanced Raman Scattering Substrate

2019 ◽  
Vol 9 (22) ◽  
pp. 4806 ◽  
Author(s):  
Ibrahim Khalil ◽  
Chia-Man Chou ◽  
Kun-Lin Tsai ◽  
Steven Hsu ◽  
Wageeh A. Yehye ◽  
...  
Keyword(s):  
Thin Film ◽  
Porous Silicon ◽  
Raman Scattering ◽  
Film Thickness ◽  
Sers Substrate ◽  
Au Film ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Au Thin Film

Metallic film-coated porous silicon (PSi) has been reported as a lucrative surface-enhanced Raman scattering (SERS) substrate. The solution-based fabrication process is facile and easy; however, it requires additional reducing agent and extra chemical treatment, as well as hinders the suitability as a reproducible SERS substrate due to irregular hot spot generation via irregular deposition of metallic nanocrystallites. To address this issue, we report a unique one-step electronic beam (e-beam) physical vapor deposition (PVD) method to fabricate a consistent layer of gold (Au) nanofilm on PSi. Moreover, to achieve the best output as a SERS substrate, PSi prepared by electrochemical etching was used as template to generate an Au layer of irregular surface, offering the surface roughness feature of the PSi–Au thin film. Furthermore, to investigate the etching role and Au film thickness, Au-nanocrystallites of varying thickness (5, 7, and 10 nm) showing discrete surface morphology were characterized and evaluated for SERS effect using Rhodamine 6G (R6G). The SERS signal of R6G adsorbed on PSi–Au thin film showed a marked enhancement, around three-fold enhancement factor (EF), than the Si–Au thin film. The optimal SERS output was obtained for PSi–Au substrate of 7 nm Au film thickness. This study thus indicates that the SERS enhancement relies on the Au film thickness and the roughness feature of the PSi–Au substrate.

Self-ordering Electrochemistry: A Simple Approach for Engineering Nanopore and Nanotube Arrays for Emerging Applications

2011 ◽  
Vol 64 (3) ◽  
pp. 294 ◽  
Author(s):  
Dusan Losic ◽  
Leonara Velleman ◽  
Krishna Kant ◽  
Tushar Kumeria ◽  
Karan Gulati ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Molecular Transport ◽  
Nanotube Arrays ◽  
Nanotube Membranes ◽  
Molecular Separation ◽  
Sensing Platform ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Interferometric Detection

In this paper, we present recent work from our group focussed on the fabrication of nanopore and nanotube arrays using self-ordered electrochemistry, and their application in several key areas including template synthesis, molecular separation, optical sensing, and drug delivery. We have fabricated nanoporous anodic aluminium oxide (AAO) with controlled pore dimensions (20–200 nm) and shapes, and used them as templates for the preparation of gold nanorod/nanotube arrays and gold nanotube membranes with characteristic properties such as surface enhanced Raman scattering and selective molecular transport. The application of AAO nanopores as a sensing platform for reflective interferometric detection is demonstrated. Finally, a drug release study on fabricated titania nanotubes confirms their potential for implantable drug delivery applications.

Extremely Large Enhancement Factors in Surface-Enhanced Raman Scattering for Molecules on Colloidal Gold Clusters

1998 ◽  
Vol 52 (12) ◽  
pp. 1493-1497 ◽  
Author(s):  
Katrin Kneipp ◽  
Harald Kneipp ◽  
Ramasamy Manoharan ◽  
Eugene B. Hanlon ◽  
Irving Itzkan ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Colloidal Gold ◽  
Surface Enhanced Raman Scattering ◽  
Gold Clusters ◽  
Surface Enhanced ◽  
Enhancement Factors ◽  
Large Enhancement ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering
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