Modern aspects of the rational choice of non-steroidal anti-inflammatory drugs: gynecologist’s view (Сlinical lecture)

2017 ◽  
pp. 11-15
Author(s):  
V.I. Pyrohova ◽  
Keyword(s):  
Key Words ◽  
Rational Choice ◽  
Pelvic Pain ◽  
Chronic Pelvic Pain ◽  
Modern Medicine ◽  
Mechanisms Of Action ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

The main mechanisms of action of non-steroidal anti-inflammatory drugs, their classification are considered in the article. The indications and aspects of the safe use of non-steroidal anti-inflammatory drugs in gynecological practice from the positions of modern medicine are considered. Key words: nonsteroidal anti-inflammatory drugs, chronic pelvic pain, Diclofenac, Dicloberl.

scholarly journals Assessment of quality of life and psychological condition of women with chronic inflammatory processes of the pelvic organs on the background of pelvic pain

2021 ◽  
Vol 2 ◽  
pp. 69-72
Author(s):  
N. Matviikiv
Keyword(s):  
Quality Of Life ◽  
Pelvic Inflammatory Disease ◽  
Pelvic Pain ◽  
Inflammatory Disease ◽  
Chronic Pelvic Pain ◽  
Pelvic Organs ◽  
Inflammatory Processes ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

The objective: was to assess the psychological status and quality of life of women in the treatment of recurrent pelvic inflammatory disease with chronic pelvic pain syndrome.Materials and methods. We observed 100 women of reproductive age who suffered from chronic pelvic pain syndrome in chronic inflammatory processes of the pelvic organs. All women were prescribed antibacterial therapy in combination with antihypoxants and antiplatelet agents. The first group included women (n=48) who were prescribed analgesics domestically due to existing contraindications to the use of non-steroidal anti-inflammatory drugs. The second group of women (n=52) received a rectally non-steroidal anti-inflammatory drug. The second group of women (n=52) received a rectally nonsteroidal anti-inflammatory agent. Patients were interviewed 3 months after treatment: using the Visual Analog Scale (VAS), the McGill Questionnaire, the Spielberger–Hanin Questionnaire, the Depression Center of the US Center for Epidemiological Research, the Beck Depression Rating Scale, and the SF-36 Questionnaire.Results. According to the results of the assessment of quality of life and changes in psychological state, we noticed the following differences. In the group of women who received analgesic medium before muscle therapy, the change in muscle changed but slightly compared with the group of women who were offered the use of nonsteroidal anti-inflammatory drugs. Indicators of quality of life and psychological condition in women of the second group have significantly improved.Conclusions. The results of this study indicate the relationship and comprehensive approach in the treatment of pelvic inflammatory disease, which is accompanied by pelvic pain.

scholarly journals PHARMACOGENETIC PROFILE AND PERSONALIZATION POSSIBILITIESIN TREATMENT OF PATIENTS WITH CHRONIC PELVIC PAIN SYNDROME

2021 ◽  
Vol 11 (1) ◽  
pp. 56-59
Author(s):  
Regina Mamina ◽  
Bela Kantemirova ◽  
Aleksei Zhidovinov ◽  
Vladimir Belopasov ◽  
Ekaterina Orlova ◽  
...  
Keyword(s):  
Pelvic Pain ◽  
Chronic Pelvic Pain ◽  
Chronic Pelvic Pain Syndrome ◽  
Pain Syndrome ◽  
Pelvic Pain Syndrome ◽  
Cyp2c9 Gene ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Personalized Approach

Chronic pelvic pain syndrome (CPPS) is equally common in both men and women, causes worsening quality of life, social isolation and disability. The treatment of CPPS requires long-term pharmacotherapy associated with the development of class-specific side effects of nonsteroidal anti-inflammatory drugs (NSAIDs). Genetic study of the carriage of polymorphic alleles of the CYP2C9 gene involved in the metabolism of non-steroidal anti-inflammatory drugs (NSAIDs) prescribed to patients with CPPS is an urgent and in-demand task of modern healthcare. This study allows us not only to determine the genotypes of patients with CPPS but also to identify ways of personalized approach to therapy.

Algorithms for personalized administration of non-steroidal anti-inflammatory drugs for patients with chronic pelvic pain syndrome based on pharmacogenetic testing

Pharmateca ◽  
2021 ◽  
Vol 3_2021 ◽  
pp. 73-80
Author(s):  
R.M. Mamina Mamina ◽  
B.I. Kantemirova Kantemirova ◽  
V.V. Belopasov Belopasov ◽  
E.A. Orlova Orlova ◽  
R.A. Sadretdinov Sadretdinov ◽  
...  
Keyword(s):  
Pelvic Pain ◽  
Chronic Pelvic Pain ◽  
Chronic Pelvic Pain Syndrome ◽  
Pain Syndrome ◽  
Pelvic Pain Syndrome ◽  
Pharmacogenetic Testing ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Chronic pelvic pain: Oral contraceptives and non-steroidal anti-inflammatory compounds

Cephalalgia ◽  
1997 ◽  
Vol 17 (20_suppl) ◽  
pp. 29-31 ◽  
Author(s):  
Pl Venturini ◽  
V Fasce ◽  
F Gorlero ◽  
G Ginocchio
Keyword(s):  
Pelvic Pain ◽  
Oral Contraceptives ◽  
Chronic Pelvic Pain ◽  
Gnrh Analogues ◽  
Primary Dysmenorrhoea ◽  
Common Causes ◽  
Appropriate Therapy ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

A correct classification of female pelvic pain originating from gynaecological disorders is essential if the most appropriate therapy is to be chosen. Certain types of non-steroidal anti-inflammatory drugs and oral contraceptives reduce the production of prostaglandins, which are responsible in large part for primary dysmenorrhoea. Oestroprogestin formulations become the drugs of choice if the patient also requests contraception. Secondary dysmenorrhoea and chronic pelvic pain may require combined medical and surgical treatment. Oral contraceptives can also be used as post-treatment agents in endometriosis, one of the most common causes of pelvic pain, whereas more specific compounds (GnRH-analogues and Danazol) are used to produce anatomical regression of endometriosis.

Certain important aspects of the prevention of pathologies of labor activity in obstetric practice (Сlinical lecture)

2016 ◽  
pp. 11-18
Author(s):  
L. Nazarenko ◽  
◽  
L. Dubrova ◽  
O. Tarusмna ◽  
◽  
...  
Keyword(s):  
Key Words ◽  
Review Article ◽  
Optimal Time ◽  
Safe Method ◽  
Individual Approach ◽  
Obstetric Practice ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Time To Delivery ◽  
Ripening Of The Cervix

The question of the prevention of pathologies of the labor is currently very important, the answer to them has become the favored formation of «dominants of delivery», choice of the optimal time to delivery, effective and safe method of induction, that promotes the promptness of the female organism and ripening of the cervix, as well as the timely identification and correction of pathological prelмmмnary period. In a review article describes the modern approaches and methods of preventing the pathology of labor activity, presented by the authors ‘ own experience regarding the use of prostaglandins, non-steroidal anti-inflammatory drugs, individual approach to the management of perinatal risk. Key words: childbirth, prevention, induction, prostaglandin, non-steroidal anti-inflammatory drugs.

Reducing pain in certain forms of obstetric pathology: nonsteroidal anti-inflammatory drugs (Сlinical lecture)

2017 ◽  
pp. 9-14
Author(s):  
L. Nazarenko ◽  
Keyword(s):  
Preterm Birth ◽  
Side Effects ◽  
Key Words ◽  
Clinical Efficacy ◽  
Premature Birth ◽  
Pain Syndrome ◽  
Inflammatory Drug ◽  
Threatened Abortion ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

The article discusses the pathogenetic basis for the use of non-steroidal anti-inflammatory drugs (NSPVP) in obstetric practice for the treatment of pain syndrome in women with threatened abortion and pathological preliminary period. Provided with modern views on the mechanisms of analgesic clinical efficacy, side effects NSPVP. Provides information about the place of NSPVP during pregnancy, the risks to the fetus, the positive aspects in the conduct of women at risk of preterm birth, the pathological preliminary period. Key words: nonsteroidal anti-inflammatory drug, pain, premature birth, preliminary period.

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