scholarly journals Criteria for the suspicion and diagnosis of acute food protein-induced enterocolitis syndrome

2021 ◽  
Vol 49 (2) ◽  
pp. 126-128
Author(s):  
Stefano Miceli Sopo

Over the past decades, several panels of criteria have been proposed for the diagnosis of acute food protein-induced enterocolitis syndrome (FPIES). However, none of them have been validated by a prospective study. Such a study is not easy to carry out, because even the children who most of us would certainly believe to be suffering from acute FPIES, possibly serious, should be subject to oral food challenge (OFC). Moreover, the presence of different phenotypes of the acute FPIES may mean that some of them do not fit into any of the above criteria panels. Particularly, Vazquez-Ortiz et al. reported that milder cases (1/4 in their Southern European cohort) might not be captured by the 2017 Consensus diagnostic criteria, which are the most shared till date. Those authors, as well as all interested researchers, claim for accurate diagnostic bio-markers which, however, are not available at the moment.

2020 ◽  
Vol 13 (8) ◽  
pp. 100335
Author(s):  
Benjamin Bonnet ◽  
Marine Godignon ◽  
Elodie Michaud ◽  
Celine Lambert ◽  
Etienne Merlin ◽  
...  

Medicina ◽  
2019 ◽  
Vol 55 (6) ◽  
pp. 216
Author(s):  
Stefano Miceli Sopo ◽  
Mariannita Gelsomino ◽  
Serena Rivetti ◽  
Ester Del Vescovo

Acute food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated allergy and is characterized by repetitive profuse vomiting episodes, often in association with pallor, lethargy, and diarrhea, presenting within 1–4 h from the ingestion of a triggering food. In 2017, the international consensus guidelines for the diagnosis and management of FPIES were published. They cover all aspects of this syndrome, which in recent decades has attracted the attention of pediatric allergists. In particular, the consensus proposed innovative diagnostic criteria. However, the diagnosis of acute FPIES is still currently discussed because the interest in this disease is relatively recent and, above all, there are no validated panels of diagnostic criteria. We propose some ideas for reflection on the diagnostic and suspicion criteria of acute FPIES with exemplary stories of children certainly or probably suffering from acute FPIES. For example, we believe that new definitions should be produced for mild forms of FPIES, multiple forms, and those with IgE-mediated symptoms. Moreover, we propose two clinical criteria to suspect acute FPIES and to refer the child to the diagnostic oral food challenge.


Author(s):  
J. Andrew Bird ◽  
Simona Barni ◽  
Terri F. Brown-Whitehorn ◽  
George du Toit ◽  
Sonsoles Infante ◽  
...  

Renal Failure ◽  
2005 ◽  
Vol 27 (2) ◽  
pp. 227-233 ◽  
Author(s):  
Wael El-Reshaid ◽  
Kamel El-Reshaid ◽  
Mohan Kapoor ◽  
Abbass Hakim

2020 ◽  
Vol 44 (4) ◽  
pp. 551-563
Author(s):  
Nayana Fonseca Vaz ◽  
Vanessa Nogueira Rodrigues da Cunha ◽  
Marlone Cunha-Silva ◽  
Tiago Sevá-Pereira ◽  
Jazon Romilson de Souza Almeida ◽  
...  

Cephalalgia ◽  
2019 ◽  
Vol 40 (4) ◽  
pp. 337-346 ◽  
Author(s):  
Alberto Terrin ◽  
Federico Mainardi ◽  
Carlo Lisotto ◽  
Edoardo Mampreso ◽  
Matteo Fuccaro ◽  
...  

Background In literature, osmophobia is reported as a specific migrainous symptom with a prevalence of up to 95%. Despite the International Classification of Headache Disorders 2nd edition proposal of including osmophobia among accompanying symptoms, it was no longer mentioned in the ICHD 3rd edition. Methods We conducted a prospective study on 193 patients suffering from migraine without aura, migraine with aura, episodic tension-type headache or a combination of these. After a retrospective interview, each patient was asked to describe in detail osmophobia, when present, in the following four headache attacks. Results In all, 45.7% of migraine without aura attacks were associated with osmophobia, 67.2% of migraineurs reported osmophobia in at least a quarter of the attacks. No episodic tension-type headache attack was associated with osmophobia. It was associated with photophobia or phonophobia in 4.3% of migraine without aura attacks, and it was the only accompanying symptom in 4.7% of migraine without aura attacks. The inclusion of osmophobia in the ICHD-3 diagnostic criteria would enable a 9.0% increased diagnostic sensitivity. Conclusion Osmophobia is a specific clinical marker of migraine, easy to ascertain and able to disentangle the sometimes challenging differential diagnosis between migraine without aura and episodic tension-type headache. We recommend its inclusion among the diagnostic criteria for migraine as it increases sensitivity, showing absolute specificity.


2020 ◽  
Vol 8 (8) ◽  
pp. 2843-2844
Author(s):  
Melanie Ruffner ◽  
Jonathan Spergel ◽  
Antonella Cianferoni ◽  
Terri Faye Brown-Whitehorn

1987 ◽  
Vol 101 (8) ◽  
pp. 780-783 ◽  
Author(s):  
J. W. R. Capper ◽  
R. W. T. Slack ◽  
A. R. Maw

SummaryDespite the huge advances in clinical audiology over the past few decades, tuning fork tests are still used extensively in the diagnosis of hearing loss. This study investigates the usefulness, reliability and accuracy of tuning fork tests in a group of children involved in a prospective study of glue ear, and shows them to be of dubious value.


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