scholarly journals Enhancement of Preventive Vaccination Approaches for Children with Health Problems: Prospective Cohort Study Results

Author(s):  
Marina V. Fedoseenko ◽  
Leyla S. Namazova-Baranova ◽  
Elena A. Vishneva ◽  
Svetlana V. Tolstova ◽  
Arevaluis M. Selvyan ◽  
...  

Background. Modern preventive vaccination is intended to protect and enhance the health of every person considering age and health issues. Vaccination of children with chronic diseases in our country remains extremely topical and arguable problem that associated with many pending issues for doctors of various specialties, including those working as primary care specialists.Objective. The aim of the study is to develop major approaches and to prove scientifically the efficacy and safety of preventive vaccination for children with various chronic diseases.Methods. We have conducted comprehensive study of 100 children aged from 1 month to 17 years 11 months. Children were divided into 4 groups according to the specific disease. Vaccinal and infectious history was analyzed. The post-vaccination period was estimated due to the results of the questionnaire completed by parents. Vaccination immunogenicity was estimated based on the results of the level of specific antibodies to various controlled infections (measles, rubella, parotitis, hepatitis B, pertussis, haemophilus influenza type b).Results. Protective titers of antibodies against haemophilus influenza type b were revealed in 96.2% of all examined patients, tetanus and hepatitis B — in 95.2%, against pertussis — in 92.5%, rubella — in 91%, measles — in 87.5%, parotitis — in 71.9%, chickenpox — in 69% children a month after the completed vaccination. The postvaccinal period was characterized as favorable in most patients. Major changes in overall health status occurred after vaccination in 42% of children was the following: subfebrile fever, capriciousness, or fatigue. Local reactions have developed only in 15% of cases.Conclusion. The results of this study have demonstrated the preventive vaccination efficacy and safety in children with various chronic diseases

2020 ◽  
Vol 8 (1) ◽  
pp. 74-79
Author(s):  
Danik Riawati ◽  
Titis Wahyuono ◽  
Dewi Anggraini Kartika

Pendahuluan: Kekebalan aktif buatan dengan pemberian vaksinasi DPT Hepatitis B dan Haemophilus influenza type B dapat memberikan efek samping demam pada bayi balita dan perlu ditanggani sejak dini supaya cepat teratasi permasalahannya.Tujuan: penelitian ini bertujuan untuk mengetahui gambaran reaksi demam pasca pemberian kekebalan aktif buatan vaksin DPT Hepatitis B dan Haemophilus influenza type B pada bayi balita.Metode: Desain penelitian menggunakan observasional analitik. Tempat penelitian di Posyandu Melati Sabrang Lor pada bulan Desember 2019. Data diperoleh dari data primer dan sekunder. Populasi penelitian adalah semua balita yang pernah mendapatkan vaksin DPT Hepatitis B dan Haemophilus influenza type B di Posayndu Melati yaitu sebanyak 43 responden. Teknik pengambilan sampel accidental sampling. Analisis data univariat disajikan dalam pentuk distribusi frekuensi.Hasil: Penelitian didapatkan bahwa sebagian besar usia bayi balita berusia > 36 bulan yaitu sebanyak 31 (72,1%), jenis kelamin laki-laki 25 (58,1%) dan yang sebagian besar tidak mengalami reaksi demam pasca pemberian kekebalan aktif buatan vaksin DPT Hepatitis B dan Haemophilus influenza type B sebanyak 28 responden (65,1%)Kesimpulan: Sebagian besar bayi balita tidak mengalami reaksi demam pasca pemberian kekebalan aktif buatan vaksin DPT Hepatitis B dan Haemophilus influenza tipe B.Kata kunci: Reaksi demam, Vaksin DPT Hepatitis B vaccine and Haemophilus influenza type B, Bayi balita


2021 ◽  
Vol 11 (1) ◽  
pp. 6
Author(s):  
Setiawandari Setiawandari ◽  
Eka Deviany Widyawaty

The immunizations that must be given to children include the Diphtheria Pertussis Tetatus-Hepatitis B-Hemophilus Influenza type B vaccine or better known as Pentabio DPT. The DTwP / HB / HiB vaccine is given to babies in 3 doses at 1 month intervals. This immunization caused a systemic reaction, one of which was a fever of 0.85% in the first 30 minutes and increased to 14.03% on the day after immunization. The purpose of this study was to determine the effectiveness of shallots (Allium ascalonicum L) in reducing the body temperature of feverish children after Pentabio DPT immunization. This type of research was quasi-experimental study, with pre and post test with control group design. The sample in this study were babies who received DPT immunization as many as 20 respondents. DPT Pentabio immunization was given a dose of 0.5 ml in the intervention group and the control group. The statistical test used was the T test. The results showed that there was a significant effect of shallots on in reducing the body temperature of feverish children after Pentabio DPT immunization, with a p-value of 0.000. Keywords: shallots; body temperature; fever; Pentabio DPT immunization ABSTRAK Imunisasi yang wajib diberikan kepada anak-anak diantaranya adalah vaksin Diphtheria Pertusis Tetatus-Hepatitis B-Hemophilus Influenza type B atau lebih dikenal dengan DPT Pentabio. Vaksin DTwP/HB/HiB diberikan kepada bayi sebanyak 3 dosis dengan interval 1 bulan. Imunisasi ini menimbulkan reaksi sistemik salah satunya berupa demam 0,85% pada 30 menit pertama dan meningkat menjadi 14,03% pada satu hari pasca imunisasi. Tujuan dari penelitian ini adalah mengetahui efektifitas bawang merah (Allium ascalonicum L) terhadap penurunan suhu tubuh anak demam pasca imunisasi DPT Pentabio. Jenis penelitian quasi eksperimen dengan pre and post test with control group design. Sampel pada penelitian ini adalah bayi yang mendapat imunisasi DPT sebanyak 20 orang responden. Pemberian imunisasi DPT PENTABIO Pentabio dosis 0,5 ml pada kelompok intervensi dan kelompok kontrol. Uji statistik yang digunakan adalah Uji T. Hasil penelitian menunjukkan ada pengaruh yang signifikan dari bawang merah dalam menurunkan suhu tubuh anak demam pasca imunisasi DPT Pentabio, dengan p-value 0,000. Kata kunci: bawang merah; suhu tubuh; demam; imunisasi DPT Pentabio


2007 ◽  
Vol 53 (9) ◽  
pp. 459-462
Author(s):  
Susan Shoshana Weisberg

BMJ ◽  
1982 ◽  
Vol 284 (6324) ◽  
pp. 1229-1229 ◽  
Author(s):  
P Macmahon ◽  
J Sills ◽  
E Hall ◽  
T Fitzgerald

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