scholarly journals THE ROLE OF PARENT-CHILD INTERACTION AS A RISK FACTOR FOR ATYPICAL DEVELOPMENT OF CHILDREN WITH AUTISM SPECTRUM DISORDERS

2018 ◽  
Vol 17 (3) ◽  
pp. 194-199
Author(s):  
Mariia A. Lavrova ◽  
Olga A. Lvova ◽  
Liudmila V. Tokarskaia ◽  
Zoia S. Lazauskene

The findings of investigations published between 2000 and 2016 on the study of parental interaction with children with a risk of autism spectrum disorders (ASD) were analyzed. The article demonstrates that early parent-child interaction in such families has distinctive features and can be one of the significant factors of both the risk of ASD development in children at an early age and the compensation of their manifestations. At the same time, such characteristics of the parent-child interaction as maternal sensitivity (the ability to perceive and accurately interpret the child's attachment signals and be able to respond promptly and adequately to these signals) and synchronism (the coordination of movements, actions and other time-dependent indicators; joint attention) are not early markers of ASD development in a child. The authors noted that the issues of parent-child interaction are rarely studied, and the survey samples are limited.

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0247432
Author(s):  
Kamrun Nahar Koly ◽  
Susanne P. Martin-Herz ◽  
Md. Saimul Islam ◽  
Nusrat Sharmin ◽  
Hannah Blencowe ◽  
...  

Objective Parent-mediated programmes have been found to be cost effective for addressing the needs of the children and adolescents with Neurodevelopmental Disorders (NDD) in high-income countries. We explored the impact of parent-mediated intervention programmes in South Asia, where the burden of NDD is high. Methods A systematic review was conducted using the following databases; PUBMED, MEDLINE, PsycINFO, Google Scholar and Web of Science. Predefined MeSH terms were used, and articles were included if published prior to January 2020. Two independent researchers screened the articles and reviewed data. Outcomes measures The review included studies that targeted children and adolescents between 1 and 18 years of age diagnosed with any of four specific NDDs that are commonly reported in South Asia; Autism Spectrum Disorder (ASD), Intellectual Disability (ID), Attention Deficit Hyperactivity Disorder (ADHD) and Cerebral Palsy (CP). Studies that reported on parent or child outcomes, parent-child interaction, parent knowledge of NDDs, or child activities of daily living were included for full text review. Results A total of 1585 research articles were retrieved and 23 studies met inclusion criteria, including 9 Randomized Controlled Trials and 14 pre-post intervention studies. Of these, seventeen studies reported effectiveness, and six studies reported feasibility and acceptability of the parent-mediated interventions. Three studies demonstrated improved parent-child interaction, three studies demonstrated improved child communication initiations, five studies reported improved social and communication skills in children, four studies demonstrated improved parental knowledge about how to teach their children, and four studies reported improved motor and cognitive skills, social skills, language development, learning ability, or academic performance in children. Conclusion This systematic review of 23 studies demonstrated improvements in parent and child skills following parent-mediated intervention in South Asia. Additional evaluations of locally customized parent-mediated programmes are needed to support development of feasible interventions for South Asian countries.


2019 ◽  
Vol 10 (1) ◽  
Author(s):  
L. D’Abate ◽  
S. Walker ◽  
R. K. C. Yuen ◽  
K. Tammimies ◽  
J. A. Buchanan ◽  
...  

AbstractIdentification of genetic biomarkers associated with autism spectrum disorders (ASDs) could improve recurrence prediction for families with a child with ASD. Here, we describe clinical microarray findings for 253 longitudinally phenotyped ASD families from the Baby Siblings Research Consortium (BSRC), encompassing 288 infant siblings. By age 3, 103 siblings (35.8%) were diagnosed with ASD and 54 (18.8%) were developing atypically. Thirteen siblings have copy number variants (CNVs) involving ASD-relevant genes: 6 with ASD, 5 atypically developing, and 2 typically developing. Within these families, an ASD-related CNV in a sibling has a positive predictive value (PPV) for ASD or atypical development of 0.83; the Simons Simplex Collection of ASD families shows similar PPVs. Polygenic risk analyses suggest that common genetic variants may also contribute to ASD. CNV findings would have been pre-symptomatically predictive of ASD or atypical development in 11 (7%) of the 157 BSRC siblings who were eventually diagnosed clinically.


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