scholarly journals Drug-induced gingival enlargement in a hypertensive patient with chronic smoking behavior - A case report

2020 ◽  
Vol 7 (1) ◽  
pp. 13-15
Author(s):  
Lakshmi Balraj ◽  
Tejavathi Nagaraj
Keyword(s):  
Case Report ◽  
Hypertensive Patient ◽  
Smoking Behavior ◽  
Drug Induced ◽  
Gingival Enlargement ◽  
Chronic Smoking

Drug-induced gingival enlargement: A case report

2019 ◽  
Vol 13 (2) ◽  
pp. 49
Author(s):  
Suhani Goel ◽  
Shivjot Chhina ◽  
SachitA Arora
Keyword(s):  
Case Report ◽  
Drug Induced ◽  
Gingival Enlargement

scholarly journals Oral myiasis associated with drug induced gingival hyperplasia – a rare case report

2021 ◽  
Vol 27 (3) ◽  
pp. 45
Author(s):  
Rohit B. Gadda ◽  
Ankush Agrawal ◽  
Santosh Kumar SN ◽  
Tushar Manohar Rothe
Keyword(s):  
Case Report ◽  
Oral Hygiene ◽  
Rare Case ◽  
Diabetes Mellitus Patient ◽  
Complete Healing ◽  
Predisposing Factors ◽  
Gingival Hyperplasia ◽  
Drug Induced ◽  
Anterior Maxilla ◽  
Gingival Enlargement

Introduction: Myiasis (Greek: myi = fly) refers to infestation of living tissues of humans and animals by Dipterous eggs or larvae. Incidence of oral myiasis is comparatively lesser than that of cutaneous myiasis. We report a rare case of oral myiasis of anterior maxilla associated with drug induced gingival enlargement. Observation: We report a rare case of oral myiasis of anterior maxilla with amlodipine induced gingival enlargement in a sixty-two-year-old male with history of hypertension, hemiplegia and diabetes mellitus. Patient was mouth breather and presented with poor oral hygiene. Generalized gingival hyperplasia was observed. Multiple maggots were observed in the ulcerated areas on maxillary anterior alveolus. The maggots were mechanically removed with curettage after application of turpentine oil. Cleaning and debridement of the wound was done. After one month follow-up there was complete healing of the lesion. Maintenance of oral hygiene and gingivectomy as indicated was planned for this patient. Conclusion: Clinical significance of presented case is its rarity of association with drug induced gingival hyperplasia and typical presence of multiple predisposing factors. This case report provides interesting information about predisposing factors, clinical features and management of oral myiasis that could help clinicians in the diagnosis and management of this condition.

Management of Drug induced gingival enlargement by flap surgery: A case report

2012 ◽  
Vol 3 (3) ◽  
pp. 249-250
Author(s):  
Kalaivani S MDS Kalaivani S MDS ◽  
◽  
Vimalraj D Vimalraj D ◽  
Dnyaneshwar Punse ◽  
Jenish Manohar J
Keyword(s):  
Case Report ◽  
Flap Surgery ◽  
Drug Induced ◽  
Gingival Enlargement

scholarly journals Nonsurgical Management of Nifedipine Induced Gingival Overgrowth

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
George Sam ◽  
Staly Chakkalakkal Sebastian
Keyword(s):  
Case Report ◽  
Oral Hygiene ◽  
Medical Community ◽  
Unwanted Effect ◽  
Gingival Inflammation ◽  
Drug Induced ◽  
Gingival Overgrowth ◽  
Nonsurgical Management ◽  
Gingival Enlargement ◽  
Oral Hygiene Practice

Drug-induced gingival overgrowth is frequently associated with three particular drugs: phenytoin, cyclosporin, and nifedipine. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. The awareness in the medical community about this possible side effect of nifedipine is less when compared to the effects of phenytoin and cyclosporin. The frequency of gingival enlargement associated with chronic nifedipine therapy remains controversial. Within the group of patients that develop this unwanted effect, there appears to be variability in the extent and severity of the gingival changes. Although gingival inflammation is considered a primary requisite in their development, few cases with minimal or no plaque induced gingival inflammation have also been reported. A case report of gingival overgrowth induced by nifedipine in a patient with good oral hygiene and its nonsurgical management with drug substitution is discussed in this case report.

EFFECTIVENESS OF NON-SURGICAL PERIODONTAL THERAPY ON AMLODIPINE INDUCED GINGIVAL ENLARGEMENT: A CASE REPORT

2019 ◽  
Vol 3 (11) ◽  
Author(s):  
Dagar Mona ◽  
Kataria Prerna
Keyword(s):  
Case Report ◽  
Calcium Channel ◽  
Calcium Channel Blockers ◽  
Normal State ◽  
Periodontal Therapy ◽  
Channel Blockers ◽  
Scaling And Root Planing ◽  
Drug Induced ◽  
Gingival Overgrowth ◽  
Gingival Enlargement

Gingival enlargement, [sometimes abbreviated to GO (gingival overgrowth)] is an increase in the size of the gingiva. It is a common feature of gingival disease. Gingival enlargement is a well known side-effect of drugs like anticonvulsants, calcium channel blockers and immunosuppressant. A case of amlodipine induced gingival enlargement was reported and after drug substitution when the patient was treated non-surgically (scaling and root planing), the enlargement subsides to a normal state which suggested the effectiveness of non-surgical periodontal therapy in the treatment of drug induced gingival enlargement. Keywords: Anticonvulsants, Immunosuppressants, Calcium channel blockers, gingival enlargement

scholarly journals Severe Adverse Drug Reactions to Quetiapine in Two Patients Carrying CYP2D6*4 Variants: A Case Report

2021 ◽  
Vol 22 (12) ◽  
pp. 6480
Author(s):  
Céline K. Stäuble ◽  
Markus L. Lampert ◽  
Thorsten Mikoteit ◽  
Martin Hatzinger ◽  
Kurt E. Hersberger ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Case Report ◽  
Adverse Drug Reactions ◽  
Active Metabolite ◽  
Hepatic Metabolism ◽  
Cytochrome P450 3A4 ◽  
Drug Reactions ◽  
Drug Induced ◽  
Potential Impact ◽  
Intermediate Metabolizer

We report two cases of patients who developed severe adverse drug reactions including persistent movement disorders, nausea, and vertigo during treatment with quetiapine at maximum daily doses ranging between 300 and 400 mg. The extensive hepatic metabolism of quetiapine is mainly attributed to cytochrome P450 3A4 (CYP3A4). However, there is recent evidence supporting the idea of CYP2D6 playing a role in the clearance of the quetiapine active metabolite norquetiapine. Interestingly, both patients we are reporting of are carriers of the CYP2D6*4 variant, predicting an intermediate metabolizer phenotype. Additionally, co-medication with a known CYP2D6 inhibitor and renal impairment might have further affected quetiapine pharmacokinetics. The herein reported cases could spark a discussion on the potential impact of a patient’s pharmacogenetic predisposition in the treatment with quetiapine. However, further studies are warranted to promote the adoption of pharmacogenetic testing for the prevention of drug-induced toxicities associated with quetiapine.

A case report of drug-induced ischemic colitis accompanied by ulcerative colitis

2021 ◽  
Vol 44 (2) ◽  
pp. 137-138
Author(s):  
Guanyu Zhou ◽  
Fei Xiong ◽  
Xudan Yang ◽  
Pu Wang
Keyword(s):  
Ulcerative Colitis ◽  
Case Report ◽  
Ischemic Colitis ◽  
Drug Induced

Drug‐induced Grover’s disease: a case report and review of the literature

2021 ◽  
Author(s):  
Olufolakemi Awe ◽  
Peter Pavlidakey ◽  
Lauren Kole ◽  
Rebecca Kissel
Keyword(s):  
Case Report ◽  
Review Of The Literature ◽  
Drug Induced ◽  
Grover’S Disease
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