Clinical aspects of mucosal healing in inflammatory bowel diseases: what is it and what is the real value for the everyday practice?

2013 ◽  
Vol 9 (9) ◽  
pp. 871-882
Author(s):  
Pal Miheller ◽  
Michael D Mandel ◽  
Katalin Mullner ◽  
Peter L Lakatos
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Mucosal Healing ◽  
Everyday Practice ◽  
Clinical Aspects ◽  
The Real ◽  
The Everyday ◽  
Bowel Diseases ◽  
Real Value ◽  
Inflammatory Bowel

Vedolizumab for the treatment of inflammatory bowel diseases: from symptomatic control to mucosal healing

Immunotherapy ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 565-575
Author(s):  
Ferdinando D’Amico ◽  
Gionata Fiorino ◽  
Laurent Peyrin-Biroulet ◽  
Silvio Danese
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Mucosal Healing ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Symptomatic Control

scholarly journals Resolution of Inflammation and Gut Repair in IBD: Translational Steps Towards Complete Mucosal Healing

2020 ◽  
Vol 26 (8) ◽  
pp. 1131-1143 ◽  
Author(s):  
Gwo-tzer Ho ◽  
Jennifer A Cartwright ◽  
Emily J Thompson ◽  
Calum C Bain ◽  
Adriano G Rossi
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Inflammatory Cell ◽  
Mucosal Healing ◽  
Treatment Target ◽  
Resolution Of Inflammation ◽  
Epithelial Repair ◽  
New Knowledge ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Macrophage Populations

Abstract Despite significant recent therapeutic advances, complete mucosal healing remains a difficult treatment target for many patients with inflammatory bowel diseases (IBD) to achieve. Our review focuses on the translational concept of promoting resolution of inflammation and repair as a necessary adjunctive step to reach this goal. We explore the roles of inflammatory cell apoptosis and efferocytosis to promote resolution, the new knowledge of gut monocyte-macrophage populations and their secreted prorepair mediators, and the processes of gut epithelial repair and regeneration to bridge this gap. We discuss the need and rationale for this vision and the tangible steps toward integrating proresolution therapies in IBD.

Time-resolved fluorimetric immunoassay of calprotectin: technical and clinical aspects in diagnosis of inflammatory bowel diseases

2006 ◽  
Vol 44 (3) ◽  
Author(s):  
Gertjan van der Sluijs Veer ◽  
Barbara van den Hoven ◽  
Maurice G.V.M. Russel ◽  
Frank A.J.T.M. van den Bergh
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Clinical Aspects ◽  
Time Resolved ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Abstract

Mucosal Healing in Inflammatory Bowel Diseases

2015 ◽  
Vol 21 (1) ◽  
pp. 198-207 ◽  
Author(s):  
Annaïg Lan ◽  
François Blachier ◽  
Robert Benamouzig ◽  
Martin Beaumont ◽  
Christophe Barrat ◽  
...  
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Mucosal Healing ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Noninvasive evaluation of mucosal healing in inflammatory bowel diseases

2012 ◽  
Vol 6 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Jun Kato ◽  
Sakiko Hiraoka ◽  
Asuka Nakarai ◽  
Masao Ichinose
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Mucosal Healing ◽  
Noninvasive Evaluation ◽  
Bowel Diseases ◽  
Inflammatory Bowel
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