scholarly journals Brain Pathology Characteristics of Developmental Brain Damage in Extremely Pre- to Full-term Infants

2015 ◽  
Vol 30 (5) ◽  
pp. 737-740
Author(s):  
Daiki YOSHIDA ◽  
Sachio TAKASHIMA ◽  
Masaharu MORITA ◽  
Ken-ichi OKUDA ◽  
Osuke IWATA ◽  
...  
2003 ◽  
Vol 157 (12) ◽  
pp. 1163 ◽  
Author(s):  
Diego Gazzolo ◽  
Emanuela Marinoni ◽  
Romolo Di Iorio ◽  
Matteo Bruschettini ◽  
Maria Kornacka ◽  
...  

2021 ◽  
Author(s):  
Eduardo Gonzalez-Moreira ◽  
Deirel Paz-Linares ◽  
Lourdes Cubero-Rego ◽  
Ariosky Areces-Gonzalez ◽  
Pedro Antonio Valdes-Sosa ◽  
...  

Aim: to evaluate EEG connectivity during the first year of age in healthy full-term infants and preterm infants with prenatal and perinatal risk factors for perinatal brain damage. Methods: Three groups of infants were studied: healthy at full-term infants (n = 71), moderate and late preterm infants (n = 54), and very preterm infants (n = 56). All preterm infants had perinatal or/and perinatal risk factors for brain damage. EEG was obtained during phase II of natural NREM sleep. EEG analysis was performed in 24 segments of 2.56 s free of artifacts. For the calculation of EEG sources, the spectral Structured Sparse Bayesian Learning (sSSBL) was used. Connectivity was computed by the phase-lag index. Results: In healthy full-term infants, EEG interhemispheric connectivity in the different frequency bands followed similar trends with age to those reported in each frequency band: delta connectivity decreases, theta increases at the end of the year, in the alpha band, different trends were observed according to the region studied, and beta interhemispheric connectivity decreases with age. EEG connectivity in preterm infants showed differences from the results of the term group. Discussion: Important structural findings may explain the differences observed in EEG connectivity between the term and preterm groups. Conclusion: The study of EEG connectivity during the first year of age gives essential information on normal and abnormal brain development.


2017 ◽  
Vol 8 (6) ◽  
pp. 86-93
Author(s):  
Tat'yana V. Melashenko ◽  
Aleksandr V. Pozdnyakov ◽  
Viktor S. Lvov ◽  
Dmitry O. Ivanov

Perinatal hypoxic-ischemic encephalopathy (HIE) remains a major cause of neonatal mortality and development of severe neurological disorders that determine the quality of life of these children. In developed countries, the frequency of detection of hypoxic-ischemic encephalopathy (HIE) among full-term newborns is 1-6 per 1.000 live births. In our country, hypoxic-ischemic brain damage is observed in 15-30% of full-term newborns. The term HIE is a clinical diagnosis combining neurological disorders and biochemical changes caused by perinatal HI (hypoxiа-ischemia). The pattern of acute brain damage depends on the degree of cerebral maturity, the severity and duration of hypoxiа-ischemia. The most vulnerable regions are the structures of the brain with high level of metabolism. Such structures in term infants include cortical neurons and neurons of basal nuclei, a subcortical white matter. MRI allows to diagnose brain lesions in term infants in the acute period of HIE. Safety, non-invasiveness and large diagnostic capabilities of MRI allow this method to be considered the gold standard of neuroimaging in neonatology. In this review we described the main MRI patterns of brain injury in term neonates following HIE.


2012 ◽  
Author(s):  
R. Montirosso ◽  
S. Moriconi ◽  
B. Riccardi ◽  
G. Reni ◽  
F. Arrigoni ◽  
...  

1982 ◽  
Vol 16 (8) ◽  
pp. 628-631 ◽  
Author(s):  
Aida Kalnitsky ◽  
David Rosenblatt ◽  
Stanley Zlotkin

2002 ◽  
Vol 13 (05) ◽  
pp. 260-269 ◽  
Author(s):  
Barbara Cone-Wesson ◽  
John Parker ◽  
Nina Swiderski ◽  
Field Rickards

Two studies were aimed at developing the auditory steady-state response (ASSR) for universal newborn hearing screening. First, neonates who had passed auditory brainstem response, transient evoked otoacoustic emission, and distortion-product otoacoustic emission tests were also tested with ASSRs using modulated tones that varied in frequency and level. Pass rates were highest (> 90%) for amplitude-modulated tones presented at levels ≥ 69 dB SPL. The effect of modulation frequency on ASSR for 500- and 2000-Hz tones was evaluated in full-term and premature infants in the second study. Full-term infants had higher pass rates for 2000-Hz tones amplitude modulated at 74 to 106 Hz compared with pass rates for a 500-Hz tone modulated at 58 to 90 Hz. Premature infants had lower pass rates than full-term infants for both carrier frequencies. Systematic investigation of ASSR threshold and the effect of modulation frequency in neonates is needed to adapt the technique for screening.


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