SHORT-TERM EFFECT OF WHEY PROTEIN SUPPLEMENTATION ON THE QUALITY OF LIFE OF PATIENTS WAITING FOR LIVER TRANSPLANTATION: A DOUBLE BLINDED RANDOMIZED CLINICAL TRIAL

ABSTRACT Background: Chronic liver disease is associated with malnutrition that negatively impacts a patient’s health-related quality of life (HRQoL). Aim: To evaluate the short-term effect of whey protein supplementation on the HRQoL and nutritional and functional status of patients waiting for liver transplantation. Methods: This was a double-blind randomized clinical trial with patients waiting for liver transplantation who were randomized into two groups: WP (whey protein supplementation) and the control (casein supplementation). Both groups received 40 g (20 g in the morning and 20 g in the evening) for 15 days. Nutritional and functional status were evaluated. Energy balance was calculated as the difference between energy intake (24-hour recall) and total energy expenditure (assessed by indirect calorimetry). The chronic liver disease questionnaire was used to assess HRQoL. All measurements were performed before and after the intervention. Results: Fifty-six patients were evaluated. Malnutrition was present in 56.9%, and it was directly associated with a poor HRQoL (p<0.05). No improvement on the nutritional and functional status was observed, in either group after protein supplementation. HRQoL improved after WP and casein supplementation, with no differences between groups (p>0.05). Patients who met protein requirements and had a positive energy balance demonstrated a higher HRQoL score (4.9, p<0.05), without between-group differences. Conclusion: Malnutrition substantially reduces HRQoL. Short-term WP or casein supplementation improved similarly the HRQoL.

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SHORT-TERM EFFECT OF WHEY PROTEIN SUPPLEMENTATION ON THE NUTRITIONAL STATUS AND QUALITY OF LIFE OF PATIENTS WAITING FOR LIVER TRANSPLANTATION

10.22541/au.160555872.21671321/v1 ◽

2020 ◽

Author(s):

Michelle d’Alessandro ◽

Jéssica Morais ◽

Yani Mizubuti ◽

Thales da Silva ◽

Silvia Fernandes ◽

...

Keyword(s):

Quality Of Life ◽

Liver Transplantation ◽

Liver Disease ◽

Functional Status ◽

Chronic Liver Disease ◽

Whey Protein ◽

Protein Supplementation ◽

Term Effect ◽

Short Term

Background & aims: Chronic liver disease is associated with malnutrition that negatively impacts a patient’s health-related quality of life (HRQoL). We evaluated the short-term effect of whey protein supplementation on the HRQoL and nutritional and functional status of patients waiting for liver transplantation (LT). Methods: This was a double-blind randomized clinical trial with patients waiting for LT who were randomized into two groups: WP (whey protein supplementation) and the control (casein supplementation). Both groups received 40g (20g in the morning and 20 g in the evening) for 15 days. Nutritional and functional status were evaluated. Energy balance (EB) was calculated as the difference between energy intake (24-hour recall) and total energy expenditure. The chronic liver disease questionnaire (CLDQ) was used to assess HRQoL. All measurements were performed before and after the intervention. Results: Fifty-six patients were evaluated. Malnutrition was present in 56.9% of patients, and it was directly associated with a poor HRQoL (p<0.05). No improvement on the nutritional and functional status was observed, in either group after protein supplementation. HRQoL improved after WP and casein supplementation, with no differences between groups (p>0.05). Patients who met protein requirements and had a positive EB demonstrated a higher HRQoL score (4.9) (p<0.05), without between-group differences. Conclusion: Malnutrition substantially reduces HRQoL. Short-term WP or casein supplementation improved the HRQoL.

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Poor Oral Health-Related Quality of Life in Pre- and Post-Liver Transplantation Patients

The Open Dentistry Journal ◽

10.2174/1874210602115010196 ◽

2021 ◽

Vol 15 (1) ◽

pp. 196-203

Author(s):

Larissa S. Santos-Lins ◽

Inácio L.S. Aguiar ◽

Liana Codes ◽

Maria A. Evangelista ◽

Alessandra de Oliveira Castro ◽

...

Keyword(s):

Quality Of Life ◽

Liver Transplantation ◽

Liver Disease ◽

Oral Health ◽

Work Ability ◽

General Health ◽

Health Related Quality ◽

Related Quality ◽

Health Related

Background: Oral health is associated with Chronic Liver Disease (CLD) and may play a relevant role in oral (OHRQoL) and general health-related quality of life (HRQoL) among people with chronic liver disease (CLD). Objective: To explore the correlations between OHRQoL and HRQoL in pre- and post-liver transplantation (LT) patients. Methods: A cross-sectional study with 189 patients: 63 per group (pre-LT, post-LT, and without liver disease). The Oral Health Impact Profile-14 (OHIP-14), the 36-Item Short-Form Health Survey, and the Work Ability Index (WAI) were used to measure oral health-related quality of life, health-related quality of life, and work ability, respectively. Oral health was evaluated according to the World Health Organization criteria. The relationship between the OHIP-14 and independent variables was analysed by multiple linear regression. Results: Pre-LT group presented the highest OHIP-14 total mean score, followed by the post-LT group, compared to the group without liver disease (p=0.001). All HRQoL and WAI mean scores were lower in the pre-LT group than in the other groups (p≤0.013). In the pre-LT group, the OHIP-14 total mean score was negatively correlated with the Mental Health, Physical Functioning, and General Health mean scores (p=0.01) and negatively and significantly (p<0.05) associated with decayed teeth and with poor workability. In the post-TL group, OHRQOL of life was associated with decayed and missing teeth, lower educational level, and poor workability. Conclusion: Patients in the pre- and post-LT groups presented poorer OHRQoL compared to patients without liver disease. OHRQoL was strongly correlated with HRQoL in the pre-LT group.

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Short-term effectiveness of conservative therapies in pain, quality of life, and sleep in patients with temporomandibular disorders: A randomized clinical trial

CRANIO® ◽

10.1080/08869634.2019.1627068 ◽

2019 ◽

pp. 1-9

Author(s):

Camila Maria Bastos Machado de Resende ◽

Fernanda Gondim Lemos de Oliveira Medeiros ◽

Cássia Renata de Figueiredo Rêgo ◽

Andressa de Sousa Leite Bispo ◽

Gustavo Augusto Seabra Barbosa ◽

...

Keyword(s):

Quality Of Life ◽

Clinical Trial ◽

Randomized Clinical Trial ◽

Temporomandibular Disorders ◽

Short Term

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SHORT-TERM EFFECT OF PULMONARY REHABILITATION ON FUNCTIONAL CAPACITY AND QUALITY OF LIFE IN PATIENT WITH STABLE COPD

CHEST Journal ◽

10.1016/j.chest.2019.02.390 ◽

2019 ◽

Vol 155 (4) ◽

pp. 288A

Author(s):

A.P. Tarigan

Keyword(s):

Quality Of Life ◽

Functional Capacity ◽

Pulmonary Rehabilitation ◽

Term Effect ◽

Short Term ◽

Short Term Effect

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Effects of treadmill training on the balance, functional capacity and quality of life in Parkinson’s disease: A randomized clinical trial

Journal of Complementary and Integrative Medicine ◽

10.1515/jcim-2018-0245 ◽

2019 ◽

Vol 17 (1) ◽

Cited By ~ 1

Author(s):

Paria Arfa-Fatollahkhani ◽

Afsaneh Safar Cherati ◽

Seyed Amir Hasan Habibi ◽

Gholam Ali Shahidi ◽

Ahmad Sohrabi ◽

...

Keyword(s):

Quality Of Life ◽

Parkinson’S Disease ◽

Clinical Trial ◽

Functional Capacity ◽

Treadmill Training ◽

Moderate Intensity ◽

P Value ◽

Short Term

AbstractBackgroundThere is growing evidence that exercise modalities have considerable effects on Parkinson’s disease (PD). This trial aimed to provide a more detailed viewpoint of short-term and long-term treadmill training (TT) effects on some motor and non-motor features of PD.MethodsIn this prospective, randomized, single-blind clinical trial, 20 mild to moderate PD patients, admitted in Rasoul-e-Akram hospital in Tehran, Iran, were randomly allocated in case (11) and control (9) groups. Treadmill intervention was performed at moderate intensity with 60% of heart rate reserved (HRR) in two 30-min sessions/week for a duration of 10 weeks. Both the groups were evaluated for three times; at the baseline, 2 months later and then 2 months after the second evaluation. We assigned the Timed Up and Go test (TUG), 6-min walk test (6MW), and the SF-8 healthy questionnaire, for assessment of balance, functional capacity, and Quality of life (QoL), respectively.ResultsBalance and functional capacity were significantly improved in the case group after the intervention (TUG p-value: 0.003, 6MW p-value: 0.003). Moreover, the long-term analysis revealed significant results as well (TUG p-value: 0.001, 6MW p-value: 0.004). Mental condition’s scores of SF-8 in cases were not statistically different in short-term follow-up (F/U). However, analysis illustrated p-value: 0.016 for long-term assessment. The intervention induced significant changes in physical condition’s scores in both of the F/Us (PC p-value: 0.013).ConclusionsThis study provides evidence that a TT of mild to moderate intensity has significant and persistent benefits for the balance, functional capacity, and QoL in PD.

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