scholarly journals Two new mixed-ligand coordination polymers based on multi-N chelating ligand inhibit YAP expression and induce caspase-mediated spinal tumor cell apoptosis

2019 ◽  
Vol 52 (5) ◽  
Author(s):  
Yi Fu Sun ◽  
Li Wei Shao ◽  
Qi Chen ◽  
Xu Gao ◽  
Fang Li ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Coordination Polymers ◽  
Cell Apoptosis ◽  
Spinal Tumor ◽  
Mixed Ligand ◽  
Tumor Cell Apoptosis ◽  
Chelating Ligand ◽  
Ligand Coordination

Mechanism of TRAIL Induced Tumor Cell Apoptosis and Application of TRAIL Based on Tumor Therapy

2012 ◽  
Vol 28 (6) ◽  
pp. 448 ◽  
Author(s):  
Ling ZHU ◽  
Xiangxi WANG ◽  
Xuemei LI ◽  
Jinliang YANG
Keyword(s):  
Tumor Cell ◽  
Cell Apoptosis ◽  
Tumor Therapy ◽  
Tumor Cell Apoptosis

scholarly journals Two mixed-ligand coordination polymers based on 2,5-thiophenedicarboxylic acid and flexible N-donor ligands: the protective effect on periodontitis via reducing the release of IL-1β and TNF-α

2020 ◽  
Vol 18 (1) ◽  
pp. 391-398
Author(s):  
Shao-Hsuan Wu ◽  
Jun-Hui Huang
Keyword(s):  
Coordination Polymers ◽  
Gingival Crevicular Fluid ◽  
Mixed Ligand ◽  
Donor Ligands ◽  
X Ray Diffraction ◽  
Functional Studies ◽  
Tnf Α ◽  
Mucosal Cells ◽  
Ligand Coordination ◽  
Crevicular Fluid

AbstractTwo novel mixed-ligand coordination polymers, {[Co(tdc)(btrp)]·0.67DMF}n (1) and {[Zn2(bimb)2(tdc)2]·2H2O}n (2) involving 2,5-thiophenedicarboxylate (H2tdc), and bitopic flexible N-donor ligands, 1,3-bis(1,2,4-triazol-1-yl)propane (btrp) and 1,4-bis((1H-benzo[d]imidazol-1-yl)methyl)benzene (bimb), have been synthesized by the hydrothermal method and characterized via IR, elemental analysis, thermal analysis, and powder X-ray diffraction. The biological functional studies were performed; the treatment activity of the compounds on periodontitis and the specific mechanism was explored. First, the real-time RT-PCR was carried out to determine the inflammatory genes nf-κb and p53 relative expression in periodontal mucosal cells after treating with compounds 1 and 2. Then, the level of the inflammatory cytokine in the gingival crevicular fluid after treating with compounds was also determined by the ELISA detection kit.

scholarly journals Hsp60 Regulation of Tumor Cell Apoptosis

2007 ◽  
Vol 283 (8) ◽  
pp. 5188-5194 ◽  
Author(s):  
Jagadish C. Ghosh ◽  
Takehiko Dohi ◽  
Byoung Heon Kang ◽  
Dario C. Altieri
Keyword(s):  
Tumor Cell ◽  
Cell Apoptosis ◽  
Tumor Cell Apoptosis

Synthesis and Characterization of 4,11-Diaminoanthra[2,3-b]furan-5,10-diones: Tumor Cell Apoptosis through tNOX-Modulated NAD+/NADH Ratio and SIRT1

2015 ◽  
Vol 58 (24) ◽  
pp. 9522-9534 ◽  
Author(s):  
Alexander S. Tikhomirov ◽  
Andrey E. Shchekotikhin ◽  
Yi-Hui Lee ◽  
Yi-Ann Chen ◽  
Chia-An Yeh ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Apoptosis ◽  
Synthesis And Characterization ◽  
Tumor Cell Apoptosis ◽  
Nadh Ratio

Combination of porphyrins and DNA-alkylation agents: Synthesis and tumor cell apoptosis induction

2006 ◽  
Vol 14 (4) ◽  
pp. 1068-1077 ◽  
Author(s):  
Hanping He ◽  
Yan Zhou ◽  
Feng Liang ◽  
Dongqing Li ◽  
Juanjuan Wu ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Apoptosis ◽  
Dna Alkylation ◽  
Apoptosis Induction ◽  
Tumor Cell Apoptosis
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