scholarly journals Ditching candidate gene association studies: lessons from psychiatric genetics

2021 ◽  
Author(s):  
Rodrigo R.R. Duarte ◽  
Helena Brentani ◽  
Timothy R. Powell
Keyword(s):  
Candidate Gene ◽  
Association Studies ◽  
Psychiatric Genetics ◽  
Gene Association ◽  
Candidate Gene Association

Humans, fruit flies, and automatons

2012 ◽  
Vol 35 (5) ◽  
pp. 381-410 ◽  
Author(s):  
Evan Charney
Keyword(s):  
Candidate Gene ◽  
Human Nature ◽  
Twin Study ◽  
Behavior Genetics ◽  
Association Studies ◽  
Fruit Flies ◽  
Gene Association ◽  
Candidate Gene Association ◽  
Target Article ◽  
Study Methodology

AbstractMy response is divided into four sections: (1) is devoted to a potpourri of commentaries that are essentially in agreement with the substance of my target article (with one exception); in (2) I address, in response to one of the commentaries, several issues relating to the use of candidate gene association studies in behavior genetics (in particular those proposing a specific G×E interaction); in (3) I provide a detailed response to several defenses of the twin study methodology; and in (4) I conclude with several reflections on that methodology and the conception of human nature it has fostered.

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