scholarly journals Do biomarkers have predictive value in the treatment modality of the patients diagnosed with bowel obstruction?

Author(s):  
Gonca Koksaldi Sahin ◽  
Muge Gulen ◽  
Selen Acehan ◽  
Basak Toptas Firat ◽  
Cem Isikber ◽  
...  
2017 ◽  
Vol 52 (10) ◽  
pp. 1616-1620 ◽  
Author(s):  
Eduardo Bracho-Blanchet ◽  
Alfredo Dominguez-Muñoz ◽  
Emilio Fernandez-Portilla ◽  
Cristian Zalles-Vidal ◽  
Roberto Davila-Perez

Medicina ◽  
2007 ◽  
Vol 43 (11) ◽  
pp. 850 ◽  
Author(s):  
Algirdas Boguševičius ◽  
Arūnas Grinkevičius ◽  
Almantas Maleckas ◽  
Juozas Pundzius

Background. Various diagnostic utilities have been used in the diagnosis of strangulated obstruction. Despite this, there is no simple and reliable marker for it, and diagnosis in most cases is based on clinical, laboratory, and radiological investigations. The purpose of the present study was to assess D-dimer value in the diagnosis of strangulated obstruction. Methods. A prospective study of 53 patients with small-bowel obstruction was conducted. Strangulated obstruction was present in 15 (28.3%) patients. Eight (53%) had intestinal necrosis, while 7 (47%) reversible ischemia. The blood samples were taken and analyzed with NycoCard Reader method with monoclonal antibodies specific for D-dimer neoantigens. Results. In the presence of intestinal necrosis, there was a higher D-dimer level found than in the cases with reversible ischemia or simple small-bowel obstruction, although this difference did not reach statistically significant level. The D-dimer test had a sensitivity of 60%, specificity of 68%, positive predictive value of 43%, and negative predictive value of 81% in diagnosing strangulated obstruction. Conclusion. In present series, D-dimer test was neither sensitive nor specific in diagnosing strangulation.


Surgery ◽  
2011 ◽  
Vol 149 (3) ◽  
pp. 394-403 ◽  
Author(s):  
Haridimos Markogiannakis ◽  
Nikolaos Memos ◽  
Evangelos Messaris ◽  
Dimitrios Dardamanis ◽  
Andreas Larentzakis ◽  
...  

2019 ◽  
Vol 6 (8) ◽  
pp. 2663
Author(s):  
Raja Waseem M. ◽  
Zahid M. Rather ◽  
Nighat Ara Majid ◽  
M. Nazrull Islam ◽  
Ydyrysova Ismatilla Toktosunovich

Background: The purpose of this study is to evaluate the role of multi-slice computed tomography (CT) with reference to presence or absence of intestinal obstruction, level of obstruction, the cause of obstruction, and correlating with their clinical diagnosis.Methods: Patients were admitted directly from Out Patient Department or emergency department with complaints suggestive of intestinal obstruction. Computed tomography scan interpretations performed by experienced radiologists were compared with the final diagnosis that was made on the basis of information obtained clinically, by investigations, and by surgical findings.Results: Majority of patients were males 62%. Mean age 51.62±17.46 years. Majority presents with abdominal pain 94% and constipation 72%.The most common cause of obstruction was adhesion bands 18%.The pre CT diagnosis was changed because of CT findings in 28 patients. Only in 50 (89.28%) patients CT findings matched with intra-operative and cause of obstruction was also found, and in 6 (10.71%) patients intra-operative findings are different from CT findings. In bowel obstruction, the CT sensitivity was 89.28%, specificity 90.90%, positive predictive value 92.59%, negative predictive value 86.95% and accuracy 92.59%.Conclusions: We concluded that multi-slice CT is highly sensitive and specific in determining the presence, the cause and site of bowel obstruction, the site of obstruction and cause of obstruction. We recommended the use of CT scan when diagnosis between ileus and obstruction on the basis of clinical and plain radiographic are difficult or in patients in whome small bowel obstruction is diagnosed when conservative management is contemplated.


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