scholarly journals Dual-task during gait between elderly with mild cognitive impairment and Alzheimer: systematic review

2017 ◽  
Vol 30 (4) ◽  
pp. 849-857
Author(s):  
Vanessa Santa Rosa Bragatto ◽  
Larissa Pires de Andrade ◽  
Paulo Giusti Rossi ◽  
Juliana Hotta Ansai
Keyword(s):  
Systematic Review ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Dual Task ◽  
Stride Length ◽  
Web Of Science ◽  
Secondary Tasks ◽  
Scientific Papers ◽  
Study Characteristics ◽  
Motor Tests

Abstract Introduction: Studies report that mobility changes could be present in early stages of Alzheimer’s disease (AD) or even in previous stages, such as mild cognitive impairment (MCI). The use of motor tests, involving dual task, could facilitate screening and differentiation between elderly with AD and MCI. Objective: to verify if gait tests associated with secondary tasks could differentiate elderly with AD and MCI. Methods: We conducted a systematic review in Pubmed, Web of Science, Medline and Scielo databases. Of the articles included, we collected information about year of the study, characteristics of the sample and the dual task test studied. Results: The databases were accessed during November 2014 and August 2015 and a total of 198 scientific papers was obtained. After reading first the summaries and then the full texts, five studies were inserted in the review. Elderly with AD presented a reduction of gait speed and stride length, using executive functions and countdown as secondary cognitive tasks. The type of MCI appears to influence the differentiation with AD. Conclusion: The review showed that some gait tests associated with a secondary task differentiate elderly with AD and MCI. It emphasizes the need of new studies involving this issue in order to obtain cut-off points and facilitate prevention, early diagnosis and observation of cognitive impairment’s evolution in clinical practice of elderly.

scholarly journals A Systematic Review of Intervention Studies Examining Nutritional and Herbal Therapies for Mild Cognitive Impairment and Dementia Using Neuroimaging Methods: Study Characteristics and Intervention Efficacy

2017 ◽  
Vol 2017 ◽  
pp. 1-21 ◽  
Author(s):  
Genevieve Z. Steiner ◽  
Danielle C. Mathersul ◽  
Freya MacMillan ◽  
David A. Camfield ◽  
Nerida L. Klupp ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Functional Neuroimaging ◽  
Photon Emission ◽  
Herbal Medicines ◽  
Risk Of Bias ◽  
Emission Tomography ◽  
Intervention Efficacy ◽  
Study Characteristics

Neuroimaging facilitates the assessment of complementary medicines (CMs) by providing a noninvasive insight into their mechanisms of action in the human brain. This is important for identifying the potential treatment options for target disease cohorts with complex pathophysiologies. The aim of this systematic review was to evaluate study characteristics, intervention efficacy, and the structural and functional neuroimaging methods used in research assessing nutritional and herbal medicines for mild cognitive impairment (MCI) and dementia. Six databases were searched for articles reporting on CMs, dementia, and neuroimaging methods. Data were extracted from 21/2,742 eligible full text articles and risk of bias was assessed. Nine studies examined people with Alzheimer’s disease, 7 MCI, 4 vascular dementia, and 1 all-cause dementia. Ten studies tested herbal medicines, 8 vitamins and supplements, and 3 nootropics. Ten studies used electroencephalography (EEG), 5 structural magnetic resonance imaging (MRI), 2 functional MRI (fMRI), 3 cerebral blood flow (CBF), 1 single photon emission tomography (SPECT), and 1 positron emission tomography (PET). Four studies had a low risk of bias, with the majority consistently demonstrating inadequate reporting on randomisation, allocation concealment, blinding, and power calculations. A narrative synthesis approach was assumed due to heterogeneity in study methods, interventions, target cohorts, and quality. Eleven key recommendations are suggested to advance future work in this area.

Incidence of mild cognitive impairment - a systematic review

2011 ◽  
Vol 38 (S 01) ◽  
Author(s):  
T Luck ◽  
M Luppa ◽  
S Briel ◽  
SG Riedel-Heller
Keyword(s):  
Systematic Review ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment

scholarly journals Prevalence of Mild Cognitive Impairment in Latin America and the Caribbean: A Systematic Review

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 897-898
Author(s):  
Fabiana Ribeiro ◽  
Ana Carolina Teixeira-Santos ◽  
Anja Leist
Keyword(s):  
Systematic Review ◽  
Latin America ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
English Language ◽  
Prevalence Data ◽  
Gender And Education ◽  
Precise Diagnosis ◽  
Normal Ageing ◽  
The Caribbean

Abstract Background. The population of Latin America and the Caribbean (LAC) is ageing rapidly, presenting the highest prevalence rates of dementia in the world. In this context, mild cognitive impairment (MCI) is an intermediate condition between normal ageing and dementia. However, very few studies verified the prevalence of MCI in LAC countries; earlier global systematic reviews only considered prevalence reports published in English language. Method. We conducted a systematic review to evaluate the prevalence of MCI in LAC countries and to explore the factors associated with MCI (i.e., age, gender, and education). A database search was conducted in February 2020 using PubMed, Web of Science, Scopus, Lilacs, SciELO, and EMBASE, for population-or community-based studies with MCI data for countries in LAC, published in English, Spanish, or Portuguese language. From k=2,168 identified and k=1,684 screened studies, only articles were selected that included subjects with a precise diagnosis of MCI. The studies were qualitatively assessed using the JBI critical appraisal checklist for studies reporting prevalence data tool. Results. A total of nine studies met the criteria, published between 2007 and 2019, including a total of 17,812 participants in nine countries Brazil, Mexico, Argentina, Colombia, Peru, Cuba, Dominican Republic, Venezuela, and Costa Rica. Estimates for MCI prevalence ranged from 1.2% to 34%, with most estimates between 1.2% and 6.45%. Estimates differed by age group, gender, and educational level. Discussion. This is the first systematic review of the prevalence of MCI in LAC countries, considering only high-quality studies adopting rigorous diagnostic criteria.

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