scholarly journals Erythrovirus B19 infection in acquired immunodeficiency syndrome: screening by histopathology, immunohistochemistry, and in situ hybridization

2006 ◽  
Vol 101 (4) ◽  
pp. 407-414 ◽  
Author(s):  
Sérgio Setúbal ◽  
Solange Artimos de Oliveira ◽  
Andréia Rodrigues Cordovil Pires ◽  
Eliene Carvalho da Fonseca ◽  
Luiz Antônio Bastos Camacho ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Acquired Immunodeficiency Syndrome ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

Thymic Abnormalities in Fetuses Aborted From Human Immunodeficiency Virus Type 1 Seropositive Women

PEDIATRICS ◽  
1992 ◽  
Vol 89 (2) ◽  
pp. 297-301
Author(s):  
Martine Papiernik ◽  
Yves Brossard ◽  
Nicole Mulliez ◽  
Joelle Roume ◽  
Christian Brechot ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
In Situ Hybridization ◽  
Hiv Infection ◽  
Immunodeficiency Virus ◽  
Initial Injury ◽  
Acquired Immunodeficiency ◽  
Rare Cells ◽  
Immunodeficiency Syndrome

Pathological abnormalities of the thymus were found in 3 of 37 fetuses aborted from human immunodeficiency virus (HIV)-infected mothers. These lesions were located predominantly in the thymic cortex, which contains mostly immature lymphocytes. Areas of focal lymphocyte depletion were infiltrated with CD4+ macrophages and were associated with abnormalities of the epithelial stromal network. No evidence of extensive HIV infection in any of the 37 thymuses was detected by either immunofluorescence or in situ hybridization techniques, although rare cells that expressed HIV antigens were found in 3 fetuses. Although less extensive, this thymic fetopathy was similar to that described in postnatal acquired immunodeficiency syndrome thymuses, strongly suggesting that the lesions were related to HIV infection. Thymic fetopathy might represent the initial injury to the lymphoid system in HIV-infected infants in whom early and severe immunosuppression develops.

In Situ Detection of Human Herpesvirus 6 in Retinitis Associated with Acquired Immunodeficiency Syndrome

1992 ◽  
Vol 114 (3) ◽  
pp. 375-377 ◽  
Author(s):  
Isabelle Reux ◽  
Anne-Marie Fillet ◽  
Henri Agut ◽  
Christine Katlama ◽  
Jean-Jacques Hauw ◽  
...  
Keyword(s):  
Acquired Immunodeficiency Syndrome ◽  
Human Herpesvirus ◽  
Human Herpesvirus 6 ◽  
Acquired Immunodeficiency ◽  
Herpesvirus 6 ◽  
Immunodeficiency Syndrome ◽  
In Situ Detection
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