scholarly journals A simple method for the spectrophotometric determination of cephalosporins in pharmaceuticals using variamine blue

2008 ◽  
Vol 33 (2) ◽  
pp. 41-46 ◽  
Author(s):  
C. Pasha ◽  
B. Narayana
Keyword(s):  
Spectrophotometric Determination ◽  
Simple Method ◽  
Variamine Blue

scholarly journals A simple method for the spectrophotometric determination of cephalosporins in pharmaceuticals using variamine blue

2018 ◽  
Vol 33 (2) ◽  
pp. 41
Author(s):  
Chand Pasha ◽  
Badiadka Narayana
Keyword(s):  
Sodium Hydroxide ◽  
Spectrophotometric Determination ◽  
Spectrophotometric Method ◽  
Acidic Medium ◽  
Simple Method ◽  
Lactam Ring ◽  
Ph Range ◽  
Variamine Blue ◽  
Hydrolysis Of

A simple spectrophotometric method for the determination of cefotaxime, ceftriaxone, cefadroxil and cephalexin with variamine blue is presented. The determination is based on the hydrolysis of β-lactam ring of cephalosporins with sodium hydroxide which subsequently reacts with iodate to liberate iodine in acidic medium. The liberated iodine oxidizes variamine blue to violet colored species of maximum absorption at 556 nm. The absorbance is measured within the pH range of 4.0-4.2. Beer’s law is obeyed in the range of 0.5-5.8 μg mL–1, 0.2-7.0 μg mL–1, 0.2-5.0 μg mL–1 and 0.5-8.5 μg mL–1 for cefotaxime, ceftriaxone, cefadroxil and cephalexin respectively. The analytical parameters were optimized and the method is successfully applied for the determination of cefotaxime, ceftriaxone, cefadroxil and cephalexin in pharmaceuticals.

Simple spectrophotometric determination of sulfate free radicals

2018 ◽  
Vol 10 (28) ◽  
pp. 3470-3474 ◽  
Author(s):  
Chen Wang ◽  
Rui Chen ◽  
Ruyu Zhang ◽  
Naidong Zhang
Keyword(s):  
Free Radicals ◽  
Spectrophotometric Determination ◽  
Sulfate Radical ◽  
Light Sources ◽  
Sulfate Radicals ◽  
Simple Method

A rapid and simple method for sulfate radical determination was described and the generation rates of sulfate radicals generated by photolysis of persulfate under different light sources were studied.

A simple method for spectrophotometric determination of two-components with overlapped spectra

1989 ◽  
Vol 66 (2) ◽  
pp. 178 ◽  
Author(s):  
M. Blanco ◽  
H. Iturriaga ◽  
S. Maspoch ◽  
P. Tarin
Keyword(s):  
Spectrophotometric Determination ◽  
Simple Method
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