Small cell carcinoma of the esophagus

BACKGROUND: Small cell carcinoma of the esophagus is a rare disease, characterized by aggressive progression, which is similar in appearance and behavior to its counterpart of the lung. It has a high incidence of metastatic disease at presentation and a poor prognosis. Treatment protocols are not well established because of the small number of cases and lack of large studies. CASE REPORT: 66 year-old woman, was admitted to the hospital with persistent dysphagia. Radiologic and endoscopic examination revealed an stenosing tumor in the lower third of the esophagus. The biopsy specimen was diagnosed as small cell carcinoma of the esophagus. The patient underwent an esophagectomy with esophagogastric anastomosis. CONCLUSION: The role of surgery remains controversial and the improvement of life quality is to be considered. Therapeutic approach is mainly esophageal resection.

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Role of surgery in the management and prognosis of limited-stage small cell carcinoma of the esophagus

Diseases of the Esophagus ◽

10.1111/dote.12230 ◽

2014 ◽

Vol 28 (5) ◽

pp. 476-482 ◽

Cited By ~ 11

Author(s):

M. R. Xie ◽

S. B. Xu ◽

X. H. Sun ◽

L. Ke ◽

X. Y. Mei ◽

...

Keyword(s):

Cell Carcinoma ◽

Small Cell Carcinoma ◽

Small Cell ◽

Carcinoma Of The Esophagus ◽

Limited Stage

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A Rare Cause of the Cough: Primary Small Cell Carcinoma of Esophagus—Case Report

Case Reports in Medicine ◽

10.1155/2012/870783 ◽

2012 ◽

Vol 2012 ◽

pp. 1-4 ◽

Cited By ~ 5

Author(s):

Erdal Yekeler ◽

Timur Koca ◽

Semra Vural

Keyword(s):

Cell Carcinoma ◽

Small Cell Carcinoma ◽

Histopathological Examination ◽

Hepatic Metastases ◽

Endoscopic Examination ◽

Small Cell ◽

Carcinoma Of The Esophagus ◽

Carcinoma Of Esophagus ◽

Chest X Ray ◽

Rare Malignancy

Primary small cell carcinoma of the esophagus is a relatively rare malignancy. It is highly progressive and poorly prognostic in untreated conditions. In the western populations, the rate of primary small cell carcinoma in all esophageal cancer types is between 0.05% and 2.4%, while it is endemically increasing up to 7.6% in the eastern populations. Most of the cases are in extensive stage at the time of diagnosis. Surgery is the treatment of choice in limited stages, but treatment must be multimodal in primary small cell carcinoma of the esophagus. A 47-year-old woman was referred to our clinic with gradually increasing severe dry cough and slight difficulty in swallowing for 20 days. Chest X-ray graphy was normal, and computed tomography of the chest showed multiple mediastinal lymph nodes and hepatic metastases. Her endoscopic examination revealed an endoluminal vegetative mass between 20 cm and 23 cm of her esophagus. The case was reported as small cell carcinoma of the esophagus on histopathological examination. The case was assumed inoperable, and chemotherapy and radiotherapy were planned. We presented a rare cause of the cough and primary esophageal small cell carcinoma in this paper.

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MET-04 A case of Brain Metastases with repeated bleeding from Esophageal carcinoma

Neuro-Oncology Advances ◽

10.1093/noajnl/vdaa143.082 ◽

2020 ◽

Vol 2 (Supplement_3) ◽

pp. ii19-ii19

Author(s):

Masataka Mikai ◽

Mitsuyoshi Abe ◽

Yo watanabe ◽

Chie Nakada ◽

Yutaka Huchinoue ◽

...

Keyword(s):

Brain Tumor ◽

Brain Metastases ◽

Esophageal Carcinoma ◽

Cell Carcinoma ◽

Small Cell Carcinoma ◽

Cerebral Hemorrhage ◽

Small Cell ◽

The Body ◽

Metastatic Brain Tumor ◽

Carcinoma Of The Esophagus

Abstract Brain metastases from esophageal cancer is rare and the incidence has been reported at approximately 5%. We report a case of brain metastases with repeated bleeding from Esophageal carcinoma. The case is a 76-year-old man. Three years ago he was diagnosed with small cell carcinoma of the esophagus by endoscopic biopsy. Metastasis was found only in the cervical lymph node, but the condition was stable by chemoradiotherapy and no metastases were found throughout the body before 1 month. He was admitted to the hospital because of a sudden convulsion, and CT scan revealed cerebral hemorrhage in the right frontal lobe. We performed conservative treatment, but rebleeding was observed from the same site repeatedly after 1 month and 2 months. Due to the influence of bleeding, it was difficult to distinguish cerebral hemorrhage from brain tumor by contrast MRI. After surgery, the cause of bleeding was diagnosed as metastatic brain tumor of esophageal small cell carcinoma. Postoperative radiation therapy was performed in another hospital, but rebleeding was observed 3 months after the operation. A reoperation was performed at another hospital, and a recurrence of metastatic brain tumor was diagnosed. In the case of highly malignant metastatic brain tumors, it was considered necessary to frequently follow the images.

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