Treatment and survival outcomes of small cell carcinoma of the esophagus: an analysis of the National Cancer Data Base

2016 ◽  
Author(s):  
Andrew T. Wong ◽  
Meng Shao ◽  
Justin Rineer ◽  
Virginia Osborn ◽  
David Schwartz ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Data Base ◽  
Small Cell Carcinoma ◽  
National Cancer Data Base ◽  
Small Cell ◽  
Survival Outcomes ◽  
Carcinoma Of The Esophagus ◽  
Cancer Data

Small cell carcinoma of the pancreas: population-based study of a rare tumor using the National Cancer Data Base

2015 ◽  
Vol 221 (4) ◽  
pp. e22
Author(s):  
Tommy Ivanics ◽  
John R. Bergquist ◽  
Christopher Shubert ◽  
Elizabeth B. Habermann ◽  
Rory L. Smoot ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Data Base ◽  
Small Cell Carcinoma ◽  
Population Based ◽  
National Cancer Data Base ◽  
Small Cell ◽  
Rare Tumor ◽  
Population Based Study ◽  
Carcinoma Of The Pancreas ◽  
Cancer Data

scholarly journals Survival outcomes and prognostic factors of primary small cell carcinoma of the esophagus

2021 ◽  
Vol 13 (5) ◽  
pp. 2790-2802
Author(s):  
Huikai Miao ◽  
Rongzhen Li ◽  
Dongni Chen ◽  
Jia Hu ◽  
Youfang Chen ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Survival Outcomes ◽  
Carcinoma Of The Esophagus

Small Cell Carcinoma of the Ovary: A Rare Tumor With a Poor Prognosis

2018 ◽  
Vol 28 (5) ◽  
pp. 932-938 ◽  
Author(s):  
Dimitrios Nasioudis ◽  
Eloise Chapman-Davis ◽  
Melissa K. Frey ◽  
Thomas A. Caputo ◽  
Steven S. Witkin ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Premenopausal Women ◽  
Clinicopathological Characteristics ◽  
National Cancer Data Base ◽  
Small Cell ◽  
Disease Stage ◽  
Rank Test ◽  
Cancer Data ◽  
Carcinoma Of The Ovary

ObjectiveThe aim of this study was to investigate the demographic and clinicopathological characteristics and prognosis of women diagnosed with small cell carcinoma of the ovary.MethodsThe National Cancer Data Base was accessed, and women diagnosed with small cell carcinoma of the ovary, between 2004 and 2014 were identified. Median and 3- and 5-year overall survival (OS) rates were calculated following generation of Kaplan-Meir curves and compared with the log-rank test. A Cox multivariate model was constructed to identify variables associated with mortality.ResultsA total 469 women were identified with a median age of 39 years; 81.7% of tumors were unilateral, whereas median size was 13 cm. Only 20.1% of patients had stage I disease. Women who underwent cancer-directed surgery had a 5-year OS rate of 24.1%. Five-year OS rates were 48.6%, 30.7%, 18%, and 12.3% for those with stages I, II, III, and IV disease, respectively, P < 0.001. Younger age (P = 0.013) and the combination of surgery with chemotherapy (CT) (P < 0.001) were associated with superior OS. By multivariate analysis, earlier disease stage and use of CT, but not patient age or performance of lymphadenectomy, were associated with lower mortality.ConclusionsSmall cell carcinomas of the ovary are unilateral tumors primarily arising in premenopausal women. Multimodal treatment with cancer-directed surgery and CT results in a modest increase of a generally poor survival.

scholarly journals MET-04 A case of Brain Metastases with repeated bleeding from Esophageal carcinoma

2020 ◽  
Vol 2 (Supplement_3) ◽  
pp. ii19-ii19
Author(s):  
Masataka Mikai ◽  
Mitsuyoshi Abe ◽  
Yo watanabe ◽  
Chie Nakada ◽  
Yutaka Huchinoue ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Brain Metastases ◽  
Esophageal Carcinoma ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Cerebral Hemorrhage ◽  
Small Cell ◽  
The Body ◽  
Metastatic Brain Tumor ◽  
Carcinoma Of The Esophagus

Abstract Brain metastases from esophageal cancer is rare and the incidence has been reported at approximately 5%. We report a case of brain metastases with repeated bleeding from Esophageal carcinoma. The case is a 76-year-old man. Three years ago he was diagnosed with small cell carcinoma of the esophagus by endoscopic biopsy. Metastasis was found only in the cervical lymph node, but the condition was stable by chemoradiotherapy and no metastases were found throughout the body before 1 month. He was admitted to the hospital because of a sudden convulsion, and CT scan revealed cerebral hemorrhage in the right frontal lobe. We performed conservative treatment, but rebleeding was observed from the same site repeatedly after 1 month and 2 months. Due to the influence of bleeding, it was difficult to distinguish cerebral hemorrhage from brain tumor by contrast MRI. After surgery, the cause of bleeding was diagnosed as metastatic brain tumor of esophageal small cell carcinoma. Postoperative radiation therapy was performed in another hospital, but rebleeding was observed 3 months after the operation. A reoperation was performed at another hospital, and a recurrence of metastatic brain tumor was diagnosed. In the case of highly malignant metastatic brain tumors, it was considered necessary to frequently follow the images.

Role of surgery in the management and prognosis of limited-stage small cell carcinoma of the esophagus

2014 ◽  
Vol 28 (5) ◽  
pp. 476-482 ◽  
Author(s):  
M. R. Xie ◽  
S. B. Xu ◽  
X. H. Sun ◽  
L. Ke ◽  
X. Y. Mei ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Carcinoma Of The Esophagus ◽  
Limited Stage

scholarly journals A Rare Cause of the Cough: Primary Small Cell Carcinoma of Esophagus—Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Erdal Yekeler ◽  
Timur Koca ◽  
Semra Vural
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Histopathological Examination ◽  
Hepatic Metastases ◽  
Endoscopic Examination ◽  
Small Cell ◽  
Carcinoma Of The Esophagus ◽  
Carcinoma Of Esophagus ◽  
Chest X Ray ◽  
Rare Malignancy

Primary small cell carcinoma of the esophagus is a relatively rare malignancy. It is highly progressive and poorly prognostic in untreated conditions. In the western populations, the rate of primary small cell carcinoma in all esophageal cancer types is between 0.05% and 2.4%, while it is endemically increasing up to 7.6% in the eastern populations. Most of the cases are in extensive stage at the time of diagnosis. Surgery is the treatment of choice in limited stages, but treatment must be multimodal in primary small cell carcinoma of the esophagus. A 47-year-old woman was referred to our clinic with gradually increasing severe dry cough and slight difficulty in swallowing for 20 days. Chest X-ray graphy was normal, and computed tomography of the chest showed multiple mediastinal lymph nodes and hepatic metastases. Her endoscopic examination revealed an endoluminal vegetative mass between 20 cm and 23 cm of her esophagus. The case was reported as small cell carcinoma of the esophagus on histopathological examination. The case was assumed inoperable, and chemotherapy and radiotherapy were planned. We presented a rare cause of the cough and primary esophageal small cell carcinoma in this paper.

scholarly journals Primary small cell carcinoma of the esophagus: Comparison between a Chinese cohort and Surveillance, Epidemiology, and End Results (SEER) data

2019 ◽  
Vol 8 (3) ◽  
pp. 1074-1085 ◽  
Author(s):  
Qin Xiao ◽  
Haifan Xiao ◽  
Shuyu Ouyang ◽  
Jinming Tang ◽  
Baihua Zhang ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Carcinoma Of The Esophagus ◽  
Seer Data ◽  
Chinese Cohort ◽  
End Results
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