Amorphous Drug Delivery Systems: Molecular Aspects, Design, and Performance

2004 ◽  
Vol 21 (3) ◽  
pp. 133-193 ◽  
Author(s):  
Aditya Mohan Kaushal ◽  
Piyush Gupta ◽  
Arvind Kumar Bansal
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Molecular Aspects ◽  
And Performance ◽  
Amorphous Drug

Supersaturating drug delivery systems: The potential of co-amorphous drug formulations

2017 ◽  
Vol 532 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Riikka Laitinen ◽  
Korbinian Löbmann ◽  
Holger Grohganz ◽  
Petra Priemel ◽  
Clare J. Strachan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Drug Formulations ◽  
Amorphous Drug

scholarly journals Biodegradable Polymers as Drug Delivery Systems for Bone Regeneration

Pharmaceutics ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 95 ◽  
Author(s):  
Kaoru Aoki ◽  
Naoto Saito
Keyword(s):  
Drug Delivery ◽  
Regenerative Medicine ◽  
Bone Regeneration ◽  
Drug Delivery Systems ◽  
Calcium Phosphates ◽  
Delivery Systems ◽  
Polymer Scaffolds ◽  
Synthetic Scaffold ◽  
And Performance ◽  
Potential Use

Regenerative medicine has been widely researched for the treatment of bone defects. In the field of bone regenerative medicine, signaling molecules and the use of scaffolds are of particular importance as drug delivery systems (DDS) or carriers for cell differentiation, and various materials have been explored for their potential use. Although calcium phosphates such as hydroxyapatite and tricalcium phosphate are clinically used as synthetic scaffold material for bone regeneration, biodegradable materials have attracted much attention in recent years for their clinical application as scaffolds due their ability to facilitate rapid localized absorption and replacement with autologous bone. In this review, we introduce the types, features, and performance characteristics of biodegradable polymer scaffolds in their role as DDS for bone regeneration therapy.

Vaginal gel drug delivery systems: understanding rheological characteristics and performance

2011 ◽  
Vol 8 (10) ◽  
pp. 1309-1322 ◽  
Author(s):  
Tao Yu ◽  
Karl Malcolm ◽  
David Woolfson ◽  
David S Jones ◽  
Gavin P Andrews
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Rheological Characteristics ◽  
Vaginal Gel ◽  
And Performance

scholarly journals EXOSOME NANOCARRIERS: BASIC BIOLOGY, DIAGNOSIS, NOVEL AND PERSPECTIVE APPROACH IN DRUG DELIVERY SYSTEMS: A REVIEW

2021 ◽  
pp. 23-30
Author(s):  
P. V. KAMALA KUMARI ◽  
KETHA SRILEKHYA ◽  
K. BHAVYA SINDHU ◽  
Y. SRINIVASA RAO
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Phospholipid Bilayer ◽  
Isolation Techniques ◽  
Basic Biology ◽  
Delivery Vehicles ◽  
Targeted Drug ◽  
Or Gene ◽  
And Performance

Exosomes are the extracellular vesicles surrounded by a phospholipid bilayer shed from all cell varieties and plays a significant role in the communication and Transportation of materials between the cells due to their ability to transfer the proteins and nucleic acids from One cell to the another cell. Analogous in size and performance to synthetic nanoparticles, exosomes provide several Advantages, rendering them the foremost promising candidates for targeted drug or gene delivery vehicles. This review highlights the isolation techniques and delivery potential of exosomes, and equally presents research or analysis gaps for enhancing the use of natural vesicles for delivery functions. Exosome-based drug formulations can be applied to an extensive variety of diseases such as various infectious, cardiovascular, cancer and neurodegenerative disorders. Mostly, exosomes combine the benefits of both synthetic nanocarriers and cell-mediated drug delivery systems however avoiding their limitations.

scholarly journals Palm Oil in Lipid-Based Formulations and Drug Delivery Systems

Biomolecules ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 64 ◽  
Author(s):  
Danial Efendy Goon ◽  
Siti Hamimah Sheikh Abdul Kadir ◽  
Normala Ab Latip ◽  
Sharaniza Ab. Rahim ◽  
Musalmah Mazlan
Keyword(s):  
Drug Delivery ◽  
Palm Oil ◽  
Drug Delivery Systems ◽  
Water Solubility ◽  
Palm Kernel ◽  
Delivery Systems ◽  
Drug Permeability ◽  
Natural Oil ◽  
And Performance ◽  
Lipid Based Formulation

Palm oil is natural oil packed with important compounds and fatty acids ready to be exploited in lipid-based formulations and drug delivery. Palm oil and palm kernel oil contain long-chain and medium-chain triglycerides, respectively, including phytonutrients such as tocotrienol, tocopherol and carotenes. The exploitation of these compounds in a lipid-based formulation would be able to address hydrophobicity, lipophilicity, poor bioavailability and low water-solubility of many current drugs. The utilisation of palm oil as part of the drug delivery system seemed to improve the bioavailability and solubility of the drug, stabilising emulsification of formulation between emulsifier and surfactant, promoting enhanced drug permeability and performance, as well as extending the shelf-life of the drug. Despite the complexity in designing lipid-based formulations, palm oil has proven to offer dynamic behaviour in providing versatility in drug design, form and delivery. However, the knowledge and application of palm oil and its fractions in lipid-based formulation are scarce and interspersed. Therefore, this study aims to focus on the research and outcomes of using palm oil in lipid-based formulations and drug delivery systems, due to the importance of establishing its capabilities and benefits.

Quality and Performance Tests for Dermal Drug Delivery Systems

2020 ◽  
pp. 255-304
Author(s):  
Margareth R.C. Marques ◽  
Tony Bennett ◽  
Gregory Fieldson
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Performance Tests ◽  
And Performance ◽  
Dermal Drug Delivery
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