scholarly journals Neonatal hepatitis and extrahepatic biliary atresia in the same sibship.

1981 ◽  
Vol 133 (4) ◽  
pp. 445-450 ◽  
Author(s):  
JUNKO SUDA ◽  
SHUNICHI NAKAJIMA ◽  
MARIKO OKANIWA ◽  
SHIGEHIKO KAMOSHITA
Keyword(s):  
Biliary Atresia ◽  
Neonatal Hepatitis ◽  
Extrahepatic Biliary Atresia

Idiopathic Neonatal Hepatitis in One DNA Fingerprint Identical Twin

PEDIATRICS ◽  
1992 ◽  
Vol 89 (2) ◽  
pp. 329-330
Author(s):  
PIETRO VAJRO ◽  
ANGIOLA FONTANELLA ◽  
EMILIA VUTTARIELLO ◽  
ANNA DE VINCENZO ◽  
GIULIANA FORTUNATO
Keyword(s):  
Biliary Atresia ◽  
Hepatobiliary Disease ◽  
Identical Twin ◽  
Dna Fingerprint ◽  
Neonatal Hepatitis ◽  
Neonatal Cholestasis ◽  
Injury Site ◽  
Extrahepatic Biliary Atresia ◽  
Dizygotic Twins ◽  
Idiopathic Neonatal Hepatitis

For the practicing pediatrician, the most commonly encountered causes of neonatal cholestasis are idiopathic neonatal hepatitis (INH) and extrahepatic biliary atresia (EHBA). However, despite extensive research, little improvement in our understanding of the etiology of INH and EHBA has occurred.1 It has been proposed that both of them may be part of a continuum of hepatobiliary disease caused by a common insult with a different predominant injury site.2 In this respect, it is interesting that, up to the present, several cases of discordance for EHBA in twins of various zygosity have been reported,3-8 whereas no data are available about either concordance or discordance for INH both in monozygotic and dizygotic twins.

Serum 5’-Nucleotidase in Neonatal Hepatitis and Biliary Atresia: Preliminary Observations

PEDIATRICS ◽  
1972 ◽  
Vol 50 (5) ◽  
pp. 812-814
Author(s):  
C. Y. YEUNG
Keyword(s):  
Bile Duct ◽  
Biliary Atresia ◽  
Diagnostic Value ◽  
Hepatobiliary Disease ◽  
Neonatal Hepatitis ◽  
Bile Duct Proliferation ◽  
Extrahepatic Biliary Atresia

This study is in agreement with the observation that the serum 5’ nucleotidase level is related to the degree of bile duct proliferation in hepatobiliary disease. In infants with congenital extrahepatic biliary atresia, where ductal proliferation is a feature, the enzyme levels are markedly raised and are significantly different from those with neonatal hepatitis. Such finding is of diagnostic value in differentiating between the two conditions.

Serum bile acid patterns in neonatal hepatitis and extrahepatic biliary atresia

1977 ◽  
Vol 90 (5) ◽  
pp. 736-739 ◽  
Author(s):  
Norman B. Javitt ◽  
James P. Keating ◽  
Richard J. Grand ◽  
Ruth C. Harris
Keyword(s):  
Bile Acid ◽  
Biliary Atresia ◽  
Neonatal Hepatitis ◽  
Serum Bile Acid ◽  
Extrahepatic Biliary Atresia
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