scholarly journals Analysis of the 17β-estradiol (17βE2) dependent transcriptome in SUM44PE invasive lobular carcinoma breast cancer cell lines

2015 ◽  
Author(s):  
MJ Sikora
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Invasive Lobular Carcinoma ◽  
Lobular Carcinoma ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Carcinoma Breast ◽  
17Β Estradiol

scholarly journals The Effects of 17β-estradiol on Mitochondrial Biogenesis and Function in Breast Cancer Cell Lines are Dependent on the ERα/ERβ Ratio

2012 ◽  
Vol 29 (1-2) ◽  
pp. 261-268 ◽  
Author(s):  
Jorge Sastre-Serra ◽  
Mercedes Nadal-Serrano ◽  
Daniel Gabriel Pons ◽  
Adamo Valle ◽  
Jordi Oliver ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Mitochondrial Biogenesis ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
17Β Estradiol ◽  
And Function

scholarly journals The Hairy and Enhancer of Split homologue-1 (HES-1) mediates the proliferative effect of 17β-estradiol on breast cancer cell lines

Oncogene ◽  
2000 ◽  
Vol 19 (51) ◽  
pp. 5951-5953 ◽  
Author(s):  
Anders Ström ◽  
Naoya Arai ◽  
Jörg Leers ◽  
Jan-Åke Gustafsson
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Proliferative Effect ◽  
17Β Estradiol ◽  
Enhancer Of Split

Synthesis of 17β-estradiol platinum(II) complexes: biological evaluation on breast cancer cell lines

2003 ◽  
Vol 13 (22) ◽  
pp. 3927-3931 ◽  
Author(s):  
Caroline Descôteaux ◽  
Josée Provencher-Mandeville ◽  
Isabelle Mathieu ◽  
Valérie Perron ◽  
Sanat K Mandal ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Biological Evaluation ◽  
Breast Cancer Cell Lines ◽  
17Β Estradiol

Synthesis of 17β-estradiol-platinum(II) hybrid molecules showing cytotoxic activity on breast cancer cell lines

2008 ◽  
Vol 18 (7) ◽  
pp. 2282-2287 ◽  
Author(s):  
Josée Provencher-Mandeville ◽  
Caroline Descôteaux ◽  
Sanat K. Mandal ◽  
Valérie Leblanc ◽  
Éric Asselin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Hybrid Molecules ◽  
17Β Estradiol

The effects of phytoestrogen extracts isolated from elder flower on hormone production and proliferation of trophoblast tumour and breast cancer cell lines

2014 ◽  
Vol 74 (S 01) ◽  
Author(s):  
L Schröder ◽  
B Piechulla ◽  
M Chorbak ◽  
C Kuhn ◽  
S Schulze ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Hormone Production

Cytotoxic activity and anti-cancer potential of Ontario grown onion extracts against breast cancer cell lines

2018 ◽  
Vol 8 (3) ◽  
pp. 159 ◽  
Author(s):  
Meghan Fragis ◽  
Abdulmonem I. Murayyan ◽  
Suresh Neethirajan
Keyword(s):  
Breast Cancer ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Cytotoxic Activities ◽  
Cancer Line ◽  
Mcf 7

Background: Breast cancer is the most commonly diagnosed cancer and the second leading cause of cancer deaths among Canadian women. Cancer management through changes in lifestyle, such as increased intake of foods rich in dietary flavonoids, have been shown to decrease the risk associated with breast, liver, colorectal, and upper-digestive cancers in epidemiologic studies. Onions are high in flavonoid content and one of the most common vegetables. Additionally, onions are used in most Canadian cuisines.Methods: We investigated the effect of five prominent Ontario grown onion (Stanley, Ruby Ring, LaSalle, Fortress, and Safrane) extracts on two subtypes of breast cancer cell lines: a triple negative breast cancer line MDA-MB-231 and an ER+ breast cancer line MCF-7.Results: These onion extracts elicited strong anti-proliferative, anti-migratory, and cytotoxic activities on both the cancer cell lines. Flavonoids present in these onion extracts induced apoptosis, cell cycle arrest in the G2/M phase, and a reduction in mitochondrial membrane potential at dose-dependent concentrations. Onion extracts were more effective against MDA-MB-231 compared to the MCF-7 cell line. Conclusion: In this study, we investigated the extracts synthesized from Ontario-grown onion varieties in inducing anti-migratory, cytostatic, and cytotoxic activities in two sub-types of human breast cancer cell lines. Anti-tumor activity of these extracts depends upon the varietal and can be formulated into nutraceuticals and functional foods for the wellbeing of cancer patients. Overall, the results suggest that onion extracts are a good source of flavonoids with anti-cancerous properties.Keywords: onion extracts; flavonoids; anti-proliferative; breast cancer; cytotoxic activity

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