Effects of Fusarium moniliforme Culture Material Containing Known Levels of Fumonisin B1on Progress of Salmonella Gallinarum Infection in Japanese Quail: Clinical Signs and Hematologic Studies

ABSTRACT Salmonella Gallinarum is capable of causing high mortality in birds of the order Galliformes. This study aimed to relate the presence of clinical signs with the recovery of Salmonella Gallinarum from organs and c loacal swabs of Japanese quails (Coturnix coturnix) experimentally infected. A total of 70 female quails were housed in a pair per cage and divided in two groups (IG: quails inoculated with 1.5x106 CFU of Salmonella Gallinarum Nalr/mL and CG: control group). After the inoculation, birds were evaluated three times a day to verify the presence of clinical signs. Birds that presented ruffled feathers, eyes closed and remained quiet in the cage were removed for euthanasia, as well as the same number of birds from the inoculated groups that presented no clinical signs and from the control group. Cloacal swabbing was performed following euthanasia for the sampling of liver, spleen, caeca, ovarian follicles and lung for microbiological procedure. Quails with clinical signs and quails found dead presented positivity of 100%. While inoculated quails with no clinical signs presented a lower positivity (38.5%). Therefore, quails with septicemia caused by SG present clinical signs of the disease and the pathogen can be isolated and quantified in the organs.

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Pathologic Changes in Extrahepatic Organs and Agglutinin Response to Salmonella Gallinarum Infection in Japanese Quail Fed Fusarium verticillioides Culture Material Containing Known Levels of Fumonisin B1

Avian Diseases ◽

10.1637/0005-2086(2007)51[705:pcieoa]2.0.co;2 ◽

2007 ◽

Vol 51 (3) ◽

pp. 705-712 ◽

Cited By ~ 8

Author(s):

S. Deshmukh ◽

R. K. Asrani ◽

D. R. Ledoux ◽

G. E. Rottinghaus ◽

A. J. Bermudez ◽

...

Keyword(s):

Japanese Quail ◽

Fusarium Verticillioides ◽

Fumonisin B1 ◽

Salmonella Gallinarum ◽

Culture Material

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The Chronic Effects of Fusarium moniliforme Culture Material, Containing Known Levels of Fumonisin B 1 , in Turkeys

Avian Diseases ◽

10.2307/1592395 ◽

1996 ◽

Vol 40 (1) ◽

pp. 231 ◽

Cited By ~ 19

Author(s):

A. J. Bermudez ◽

D. R. Ledoux ◽

J. R. Turk ◽

G. E. Rottinghaus

Keyword(s):

Fusarium Moniliforme ◽

Chronic Effects ◽

Culture Material

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Failure of diplodiatoxin to induce diplodiosis in juvenile goats

Onderstepoort Journal of Veterinary Research ◽

10.4102/ojvr.v87i1.1712 ◽

2020 ◽

Vol 87 (1) ◽

Author(s):

Christo J. Botha ◽

Louis G.J. Ackerman ◽

Mxolisi G. Masango ◽

Luke F. Arnot

Keyword(s):

South Africa ◽

Body Weight ◽

Intravenous Administration ◽

Dosage Regimen ◽

Clinical Signs ◽

Major Metabolite ◽

Experimental Results ◽

Culture Material ◽

As If

Diplodiosis is an important neuromycotoxicosis of ruminants in South Africa when grazing on harvested maize fields in winter. It is believed to be caused by mycotoxin(s) synthesised by Stenocarpella (Diplodia) maydis. Although several metabolites have been isolated from S. maydis culture material, none of these have been administered to ruminants to reproduce the disease. The objectives of this study were to isolate diplodiatoxin and to administer it to juvenile goats. Diplodiatoxin, considered as a major metabolite, was purified from S. maydis-infected maize cultures (Coligny 2007 isolate). Following intravenous administration of 2 mg and 4 mg diplodiatoxin/kg body weight for five consecutive days to two juvenile goats, no clinical signs reminiscent of diplodiosis were observed. Based on previous experimental results and if diplodiatoxin was the causative compound, the dosage regimen employed was seemingly appropriate to induce diplodiosis. In addition, intraruminal administration of 2 mg/kg diplodiatoxin to one goat for three consecutive days also did not induce clinical signs. It appears as if diplodiatoxin alone is not the causative compound. Other metabolites and/or mixtures of diplodiatoxin and other mycotoxins, when available in sufficient quantities, should also be evaluated.

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