Pulsatile prolactin secretory patterns throughout the oestrous cycle in the rat

1993 ◽  
Vol 137 (1) ◽  
pp. 43-47 ◽  
Author(s):  
A. Lafuente ◽  
J. Marcó ◽  
A. I. Esquifino

ABSTRACT Prolactin secretion throughout the oestrous cycle in the rat remains at a low level and fairly constant, with the exception of the surge at pro-oestrus. The present study was designed to characterize possible changes in pulsatile patterns of prolactin during the oestrous cycle of the adult female rat. Mean values of prolactin increased from dioestrus-2 to pro-oestrus and then decreased to the values found at dioestrus-1. The number of peaks remained fairly constant in any phase of the oestrous cycle. The absolute amplitude of the peaks increased numerically but was not statistically significant from dioestrus-2 to pro-oestrus then decreasing until dioestrus-1. No changes in the relative amplitude or duration of the peaks throughout the oestrous cycle were detected. The results indicated that there is a similar pulsatile pattern of prolactin at any stage of the oestrous cycle, when samples were obtained during the morning. Journal of Endocrinology (1993) 137, 43–47

1994 ◽  
Vol 142 (3) ◽  
pp. 581-586 ◽  
Author(s):  
A Lafuente ◽  
J Marcó ◽  
A I Esquifino

Abstract Much is known about the fact that thyrotrophin-releasing hormone (TRH) and vasoactive intestinal peptide (VIP) stimulate prolactin secretion but areas of uncertainty remain. This work was undertaken to describe the effects of TRH and VIP on the pulsatile secretion pattern of prolactin, in adult sham-operated and pituitary-grafted hyperprolactinaemic female rats. Two pulses of TRH (1 μg/rat) or one pulse of VIP (20 μg/rat) were given 60 or 120 min after the period of blood sampling. Pituitary grafting increased the mean values of prolactin, absolute amplitude and duration of the peaks and decreased their frequency, compared with control animals. In sham-operated rats, TRH elevated prolactin levels by increasing the absolute and relative amplitudes and duration of the pulses, along with a decrease in their frequency. No priming effects of TRH were observed in this study. Hyperprolactinaemia blunted TRH effects on the pulsatile secretion pattern of prolactin. In sham-operated rats, VIP administration increased the absolute and relative amplitudes of the prolactin peaks. None of the other parameters studied were changed. In pituitary-grafted animals, VIP administration increased the absolute and relative amplitudes of the prolactin peaks but to a lesser extent compared with controls. These data suggest that TRH and VIP affect prolactin pulsatility differentially. The effects of TRH and VIP were blunted to some extent by exposure to previously elevated circulating prolactin levels. Journal of Endocrinology (1994) 142, 581–586


1966 ◽  
Vol 3 (01) ◽  
pp. 1-22
Author(s):  
Henry M. Cheng ◽  
Jacques B. Hadler

In this paper the wake survey data of a family of models of the Victory ships measured and reported by the Netherlands Ship Model Basin are further analyzed. The scale effect upon the circumferential mean wake velocity and the harmonic contents of the circumferential velocity distributions are examined. It was found that for the relative amplitude of the various harmonics of the circumferential velocity distributions, the scale effect does not seem to be important. However, the effect of scale on the absolute amplitude of various harmonics could not be established. Extrapolated curves of the circumferential mean and the volumetric mean velocities for the ship are presented. Also reported are the effects of roughness, the comparative studies regarding the symmetry and repeatability of measurements, and the effect of rudder.


1981 ◽  
Vol 198 (2) ◽  
pp. 385-389 ◽  
Author(s):  
S Thrower ◽  
L Lim

Oestradiol administration to immature or ovariectomized rats has been reported to increase the uterine content of long-term nuclear oestrogen receptors. However, in the intact adult female rat, oestradiol administration did not increase the concentration of long-term nuclear oestrogen receptors at all phases of the oestrous cycle. Progesterone administration to rats in late dioestrus did not affect the concentration of uterine nuclear oestrogen receptors 24 h later, although it did prevent the normal cyclic increase at pro-oestrus in the concentration of hypothalamic nuclear oestrogen receptors. Our results therefore show that in the intact adult rat, factors other than the concentration of progesterone or oestradiol determine the nuclear concentration of oestrogen receptors in the uterus. They also demonstrate differences between neural and non-neural tissues in the regulation of oestrogen-receptor interactions.


2009 ◽  
Vol 19 (11) ◽  
pp. 2719-2727 ◽  
Author(s):  
J.-R. Chen ◽  
Y.-T. Yan ◽  
T.-J. Wang ◽  
L.-J. Chen ◽  
Y.-J. Wang ◽  
...  

Endocrinology ◽  
2009 ◽  
Vol 150 (7) ◽  
pp. 3237-3244 ◽  
Author(s):  
Tamara Blutstein ◽  
Peter J. Baab ◽  
H. Ronald Zielke ◽  
Jessica A. Mong

Endocrinology ◽  
1982 ◽  
Vol 111 (1) ◽  
pp. 136-143 ◽  
Author(s):  
MARGARET ANN MILLER ◽  
ANTONIO E. COLAS

2010 ◽  
Vol 321 (2) ◽  
pp. 161-174 ◽  
Author(s):  
Yi Feng ◽  
Birgitta Weijdegård ◽  
Tienpei Wang ◽  
Emil Egecioglu ◽  
Julia Fernandez-Rodriguez ◽  
...  

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