Technical issues on alteration and refurbishment projects

2020 ◽  
pp. 23-40
Author(s):  
David Oloke
Keyword(s):  
Author(s):  
Dennis Flanagan ◽  
Alessandro Fisher BS ◽  
Carmen Ciardiello ◽  
Vito Moreno ◽  
Alen Uvalic ◽  
...  

When planning an implant supported restoration the dentist is faced with the surgical and prosthetic technical issues as well as the patient’s expectations. Many patients wish an immediate solution to an edentulous condition. This is especially may be true in the esthetic zone. The extent of the zone is determined by the patient. The dentist may consider when it is feasible to load the supporting implants with definitive or provisional prosthetics. For the work herein, consideration of many parameters were theoretically assessed for inclusion: bone density, cortical thickness, seating torque, parafunction, bite load capacity, number of implants under load, implant/crown ratio, implant diameter and length. After assessment, the most influential parameters were selected. An iteration, using patient age, implant diameter, bite load capacity and cortical thickness, is now presented to aid the implant dentist in determining the feasibility for immediate functional loading of a just placed dental implant in a healed site. Extensive testing is required to develop this concept. According to this iteration, most immediate functional loaded implants would fail. A future refined and definitive formula may enable the clinician to safely immediately functional load an implant with a definitive prosthesis.


2020 ◽  
Vol 27 ◽  
Author(s):  
Yi Zhang

: Point-of-care (POC) testing decentralizes the diagnostic tests to the sites near the patient. Many POC tests rely microfluidic platforms for sample-to-answer analysis. Compared to other microfluidic systems, magnetic digital microfluidics demonstrate compelling advantages for POC diagnostics. In this review, we have examined the capability of magnetic digital microfluidics-based POC diagnostic platforms. More importantly, we have categorized POC settings into three classes based on “where is the point”, “who to care” and “how to test”, and evaluated the suitability of magnetic digital microfluidics in various POC settings. Furthermore, we have addressed other technical issues associated with POC testing such as controlled environment, sample-system interface, system integration and information connectivity. We hope this review would provide a guideline for the future development of magnetic digital microfluidics-based platforms for POC testing.


2019 ◽  
Vol 24 (42) ◽  
pp. 5081-5083 ◽  
Author(s):  
Mohd. A. Mirza ◽  
Zeenat Iqbal

Background: The last few decades have witnessed enormous advancements in the field of Pharmaceutical drug, design and delivery. One of the recent developments is the advent of 3DP technology. It has earlier been successfully employed in fields like aerospace, architecture, tissue engineering, biomedical research, medical device and others, has recently forayed into the pharmaceutical industry.Commonly understood as an additive manufacturing technology, 3DP aims at delivering customized drug products and is the most acceptable form of“personalized medicine”. Methods: Data bases and search engines of regulatory agencies like USFDA and EMA have been searched thoroughly for relevant guidelines and approved products. Other portals like PubMed and Google Scholar were also ferreted for any relevant repository of publications are referred to wherever required. Results: So far only one pharmaceutical product has been approved in this category by USFDA and stringent regulatory agencies are working over the drafting of guidelines and technical issues. Major research of this category belongs to the academic domain. Conclusion: It is also implicit to such new technologies that there would be numerous challenges and doubts before these are accepted as safe and efficacious. The situation demands concerted and cautious efforts to bring in foolproof regulatory guidelines which would ultimately lead to the success of this revolutionary technology.


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