scholarly journals Spontaneous Resolution of Pituitary Cystic Lesion

2020 ◽  
Vol 7 (1) ◽  
pp. 1-4
Author(s):  
Alice Willison ◽  
◽  
Avinash K. Kanodia ◽  
Kirit Singh ◽  
Graham Leese ◽  
...  

Differentiating between cystic lesions of pituitary gland may be challenging. Usual differentials are cystic pituitary adenoma (cPA) and Rathke’s cleft cyst (RCC). Diagnostic certainty of magnetic resonance imaging (MRI) is limited in the absence of usual suggestive features. Furthermore, RCC can co-exist with approximately 2% of pituitary adenomas. Over time, these cystic lesions may remain static, resolve spontaneously, or result in symptomatology relating to mass effect and/or hormonal disruption. In cases of an asymptomatic lesion being found incidentally, little is known about how it may progress, raising question whether to proceed with surgical management or follow-up. We a present case of a spontaneously resolving pituitary cystic lesion with imaging features more suggestive of cPA than RCC, for which watchful waiting proved a successful treatment strategy. The current case serves as a reminder that small cystic lesions can be followed-up with spontaneous resolution and should be offered active treatment only when clinically required.

2020 ◽  
Vol 40 (3) ◽  
pp. 265-269
Author(s):  
Jayateertha Joshi ◽  
Nutan Kamath ◽  
Jyoti Ramnath Kini ◽  
Jayashree K ◽  
Suchetha Rao ◽  
...  

With the advent of antenatal ultrasonography (USG), detection of neonatal intra-abdominal cystic lesions is on the rise. We present a neonate who was detected antenatally to have a cystic lesion per abdomen and presented with features of intestinal obstruction on first postnatal day. Emergency exploratory laparotomy revealed a left torsed ovarian cyst compressing the ileoceacal junction. Left oophorectomy was done and ovarian torsion was confirmed by histopathology examination. The USG abdomen at six months follow up showed a well visualised right ovary.


2020 ◽  
Vol 35 (6) ◽  
pp. 380-388
Author(s):  
Mirac Yildirim ◽  
Rahsan Gocmen ◽  
Bahadir Konuskan ◽  
Safak Parlak ◽  
Dilek Yalnizoglu ◽  
...  

Acute cerebellitis is a rare condition often considered within the group of acute postinfectious cerebellar ataxia despite its distinctive clinical and imaging features. We retrieved clinical, laboratory, and follow-up data of 15 children diagnosed with acute cerebellitis in our department between 2011 and 2019. There were 10 boys and 5 girls aged 3-15 years, median 9.5 years. The most common first symptoms were ataxia, vomiting, and headache. Magnetic resonance imaging (MRI) generally showed bilateral symmetrical T2 hyperintense changes with moderate swelling in the cerebellar cortex. Tonsillar herniation was present in 73.3% and obstructive hydrocephalus in 26.6%. Etiologic workup for infectious pathogens revealed Mycoplasma pneumoniae, influenza A virus, cytomegalovirus, and varicella zoster virus in 1 case each. Fourteen of 15 patients were treated with intravenous and/or oral steroids and 8 cases with intravenous immunoglobulin. No patient required surgical decompression. Neurologic examination median 12 months later revealed ataxia and dysmetria in 4 cases (27%), accompanied by memory difficulties, dysarthria or tremor. Follow-up magnetic resonance imaging (MRI; n = 12) showed diffuse cerebellar cortical T2-hyperintense signal changes in 11 cases and cerebellar atrophy in 9. The diagnosis of acute cerebellitis rather than acute postinfectious cerebellar ataxia should be considered when headache and vomiting accompany ataxia in a child. Acute cerebellitis heals with sequelae in about one-third of cases. The absence of fatalities in our series suggests early diagnosis, and steroid treatment can increase the chance of recovery. MRI results were not found to be predictive of outcome.


2013 ◽  
Vol 103 (2) ◽  
pp. 141-144 ◽  
Author(s):  
Mert Keskinbora ◽  
Özkan Köse ◽  
Yildirim Karslioglu ◽  
Bahtiyar Demiralp ◽  
Mustafa Basbozkurt

Benign fibrous histiocytoma is a rare benign primary skeletal tumor that occurs frequently in the long bones and the pelvis. The calcaneus is an unusual location for benign fibrous histiocytoma. We did not identify any case of benign fibrous histiocytoma involving the calcaneus in the relevant literature. We describe a 22-year-old male patient with benign fibrous histiocytoma involving the calcaneus treated with curettage and bone grafting. At the final follow-up visit, 1 year after surgery, the patient was free of pain and walking unaided. We discuss the differential diagnosis of cystic lesions of the calcaneus. (J Am Podiatr Med Assoc 103(2): 141–144, 2013)


2021 ◽  
Vol 36 (6) ◽  
pp. 1130-1131
Author(s):  
Katelyn Yunes ◽  
Carolina Posada

Abstract Objective Arachnoid cysts (ACs) are typically cerebrospinal fluid-filled abnormalities that occur within the central nervous system. ACs are uncommon (prevalence rate of 1.2%), and typically occur within the left hemisphere middle cranial fossa or posterior fossa. Symptoms vary depending on location and size but often include headaches, weakness, cognitive changes, and hydrocephalus. We present an unusual case of a 68-year-old right-handed woman with 13 years of education who was admitted to the hospital following overdose. During a previous admission, Patient was found to have a large arachnoid cystic lesion and right-sided weakness, but was determined not to require acute intervention. Neuropsychology was consulted to assess current cognitive functioning. Method Patient was initially diagnosed with a severe major depressive episode with new-onset psychotic features following an overdose of baclofen and Tylenol. Suicide attempt was denied. Magnetic Resonance Imaging (MRI) confirmed previously identified arachnoid cystic lesion (Figure 1) causing mass effect. Patient’s MRI also revealed pituitary macroadenoma (Figure 2) that caused subtle distortion along the optic chiasm. Results The results (Table 1) suggested an abnormal cognitive profile characterized by deficits on measures of language, visuoperception, memory, and abstract reasoning in the context of relatively intact auditory attention and working memory. Conclusions The extent and severity of Patient’s deficits are likely attributable to the cystic lesion, with recent onset of visual hallucinations likely caused by location of pituitary macroadenoma. This case highlights the importance of having access to a neuropsychological inpatient consultation service to assist with clarification of symptom etiology and facilitation of appropriate diagnosis and intervention.


2011 ◽  
Vol 6 (2) ◽  
pp. 132
Author(s):  
Raquel Cano Alonso ◽  
Mar Jimenez de la Peña ◽  
Manuel Recio Rodriguez ◽  
Javier Carrascoso Arranz ◽  
Vicente Martinez de Vega Fernandez ◽  
...  

New contrast-enhancing lesions discovered on routine follow-up brain imaging at or near the site of previously treated primary or metastatic brain tumours represent a clinical and radiological challenge, as radiation necrosis and tumoral recurrence often present at standard magnetic resonance imaging (MRI) with overlapping imaging features. Since the advent of combined therapy, including surgery and/or radiotherapy and chemotherapy, the post-treatment radiological assessment has been made earlier, with a subsequent higher incidence of early radionecrosis and a potential risk of mistaking it for disease progression. Therefore, both clinical and imaging follow-up are essential. This article briefly describes and illustrates the temporal patterns and spectrum of MR findings of radiation-induced brain injury and considers practical aspects of conventional and advanced MR sequences (diffusion-weighted imaging, perfusion MR and MR spectroscopy), with a particular emphasis on the distinction between tumoral recurrence and radiation necrosis.


2018 ◽  
Vol 90 (1) ◽  
pp. 44-46 ◽  
Author(s):  
Martijn T Wijburg ◽  
Clemens Warnke ◽  
Frederik Barkhof ◽  
Bernard M J Uitdehaag ◽  
Joep Killestein ◽  
...  

ObjectiveTo test the current progressive multifocal leukoencephalopathy (PML) diagnostic criteria by applying them to patients previously diagnosed with natalizumab (NTZ)-associated PML in a real-world clinical setting.MethodsPatients from the Dutch-Belgian NTZ-PML cohort (n=28) were reviewed at the time of first diagnostic work-up and during follow-up, using the PML diagnostic criteria as proposed in a consensus statement from the American Academy of Neurology.ResultsAt first diagnostic work-up, 18 patients (64.3%) met the criteria for high diagnostic certainty for PML (‘definite PML’ or ‘probable PML’). During follow-up, this increased to 20 patients (71.4%) as JC virus DNA was detected in cerebrospinal fluid of two additional patients. Nonetheless, 28.6% of patients were still classified as ‘possible PML’ or ‘not PML’ (6 (21.5%) and 2 (7.1%) patients, respectively) despite a very high suspicion for PML based on lesion evolution and signs of PML-immune reconstitution inflammatory syndrome on MRI, and development of compatible symptoms.ConclusionsThe current case definition of PML has low sensitivity for diagnosis of NTZ-PML in a real-world clinical setting in which MRI is frequently used for PML screening. This may delay diagnosis and appropriate management of PML, and may complicate a valid estimation of PML incidence during NTZ therapy.


2020 ◽  
Vol 48 (9) ◽  
pp. 030006052095641
Author(s):  
Siping He ◽  
Ke Jin ◽  
Xicheng Deng ◽  
Zhengzhen Zhou ◽  
Robert C McKinstry ◽  
...  

Juvenile xanthogranuloma (JXG) is the most common non-Langerhans cell histiocytic disorder in children. This report describes the case of a 28-day-old boy that presented with multiple subcutaneous nodular lesions on the trunk and extremities, and multiple red nodular lesions on the scrotum. Magnetic resonance imaging (MRI) of the brain showed a well-demarcated extra-axial dura-based mass that appeared isointense or slightly hyperintense on T1-weighted images, hypointense on T2-weighted images and had intense enhancement on gadolinium-enhanced T1-weighted images. Computed tomography (CT) or MRI scans of the chest and abdomen revealed multiple scattered nodular or patchy lesions of varying sizes in the lungs, liver and left kidney. Histological analysis of a subcutaneous mass suggested JXG. The patient was diagnosed with neonatal systemic JXG with involvement of the central nervous system, lungs, liver, kidneys, subcutaneous soft tissue and skin. CT and MRI after 3 months of treatment with methylprednisolone sodium succinate demonstrated that the lesions were obviously diminished. This report discusses the imaging findings in this current case of multi-organ JXG and reviews the imaging literature on this condition to improve awareness of the lesions in order to help radiologists establish an accurate differential diagnosis when confronted with similar cases.


2012 ◽  
Vol 2 (1) ◽  
pp. 35-38 ◽  
Author(s):  
A Verma ◽  
A Moiyadi ◽  
S Arya ◽  
R Jalali ◽  
H Menon ◽  
...  

Neuroglial cyst is a rare abnormality that is usually asymptomatic and an incidental detection in imaging done for an unrelated cause. An emphasis on this message is the prime aim of the present report. We came across a patient being treated for chronic myeloid leukemia having vague neurological symptoms for which Magnetic Resonance Imaging (MRI) was done. No detectable cause explaining his symptomatology was noted on imaging. A cystic lesion was however noted in right frontal lobe which was labeled as a neuroglial cyst. No treatment was mandated as per discussion in the neuro-oncology working group of our centre. Follow up was advised to confirm the impression as an attempt to achieve a histological diagnosis would have been ethically not justified. The patient reported regularly for his chemotherapy regimen to the respective unit and was asymptomatic for the lesion till last follow up at six months. NJR I VOL 2 I ISSUE 1 35-38 Jan-June, 2012 DOI: http://dx.doi.org/10.3126/njr.v2i1.6978


1970 ◽  
Vol 7 (1) ◽  
pp. 73-75
Author(s):  
K Paudel ◽  
A Kumar

Prostatic utricle cyst is one of the uncommon conditions and only a few cases have been reported. We present a case of unusually large prostatic utricle cyst in a 13- year- old male. He presented with burning urination and post-void dribbling of urine. A cystic mass was felt on digital per rectal examination. Ultrasound pelvis revealed a well-defined midline cystic mass posterior to the urinary bladder. Subsequent magnetic resonance imaging (MRI) of the pelvis demonstrated fluid containing cystic lesion communicating with posterior urethra. Surgical resection of the cyst was performed through the posterior sagittal approach. Follow up of the patient after three months of operation, there was complete resolution of the symptoms. Key words: Prostatic utricle cyst, MRI, Ultrasound doi: 10.3126/kumj.v7i1.1770 Kathmandu University Medical Journal (2009), Vol. 7, No. 1, Issue 25, 73-75


2011 ◽  
Vol 07 (01) ◽  
pp. 53
Author(s):  
Raquel Cano Alonso ◽  
Mar Jimenez de la Peña ◽  
Manuel Recio Rodriguez ◽  
Javier Carrascoso Arranz ◽  
Vicente Martinez de Vega Fernandez ◽  
...  

New contrast-enhancing lesions discovered on routine follow-up brain imaging at or near the site of previously treated primary or metastatic brain tumours represent a clinical and radiological challenge, as radiation necrosis and tumoral recurrence often present at standard magnetic resonance imaging (MRI) with overlapping imaging features. Since the advent of combined therapy, including surgery and/or radiotherapy and chemotherapy, the post-treatment radiological assessment has been made earlier, with a subsequent higher incidence of early radionecrosis and a potential risk of mistaking it for disease progression. Therefore, both clinical and imaging follow-up are essential. This article briefly describes and illustrates the temporal patterns and spectrum of MR findings of radiation-induced brain injury and considers practical aspects of conventional and advanced MR sequences (diffusion-weighted imaging, perfusion MR and MR spectroscopy), with a particular emphasis on the distinction between tumoral recurrence and radiation necrosis.


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