scholarly journals Morphea and Autoimmunity: HLA behind the scene?

2021 ◽  
Vol 14 ◽  
pp. 238
Author(s):  
Nada Boutrid ◽  
Hakim Rahmoune
Keyword(s):  
Celiac Disease ◽  
Case Report ◽  
Dermatitis Herpetiformis ◽  
Autoimmune Disorders ◽  
Hla Genes

We read with deep attention the case report recently published  about the peculiar association of morphea, celiac disease, dermatitis herpetiformis and dermatomyositis , and we would discuss the particular genetics that lay behind morphea and related autoimmune disorders, with a focus on HLA genes.

scholarly journals A Rare Comorbidity: Dermatitis Herpetiformis and Sarcoidosis - A Case Report

2016 ◽  
Vol 8 (3) ◽  
pp. 171-176
Author(s):  
Stoyan Ivanov Pavlov ◽  
Irina Ivanova Ivanova ◽  
Hristo Boychev Popov ◽  
Maria Angelova Tzaneva ◽  
Peter Ivanov Ghenev
Keyword(s):  
Celiac Disease ◽  
Case Report ◽  
Dermatitis Herpetiformis ◽  
Tissue Transglutaminase ◽  
Epithelioid Cell ◽  
Unknown Etiology ◽  
Simultaneous Occurrence ◽  
Direct Immunofluorescence ◽  
Laboratory Test Results ◽  
Wide Range

Abstract Sarcoidosis is an enigmatic, multisystem granulomatous disease of unknown etiology and wide range of clinical presentations. Case report: A 54-year-old female presented with facial rash: polymorphic, round, infiltrated erythematous plaques, 1 - 3 cm in size, disseminated on several areas of the face. The medical history was consistent with dermatitis herpetiformis and persistent intrahepatic cholestasis. The laboratory test results suggested celiac disease (strong positivity of IgA anti-tissue transglutaminase antibodies) but upper endoscopy was not performed to confirm it. The skin biopsy revealed noncaseating epithelioid-cell granulomas, and negative direct immunofluorescence showed IgA deposits in the dermis. Sarcoidosis with cutaneous and hepatic involvement was established based on compatible clinical findings and supportive histology. The period between manifestations of Duhring disease and skin manifestations of sarcoidosis was 20 years. Conclusion: Our clinical case supports the hypothesis for common immune pathogenic factors in gluten-sensitive diseases and sarcoidosis. The simultaneous occurrence of celiac disease and sarcoidosis is rare, but should not be under recognized.

scholarly journals Celiac disease presenting as dermatitis herpetiformis: A case report

2020 ◽  
Vol 9 (4) ◽  
pp. 1
Author(s):  
Ali Kirik ◽  
Sinan Ozcelik ◽  
Eren Altun ◽  
Figen Aslan ◽  
Gulhan Ucdu ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Case Report ◽  
Dermatitis Herpetiformis

Facial Involvement in Dermatitis Herpetiformis: A Case Report and Review of the Literature

2018 ◽  
Vol 23 (1) ◽  
pp. 35-37
Author(s):  
Allison K. Cinats ◽  
Laurie M. Parsons ◽  
Richard M. Haber
Keyword(s):  
Celiac Disease ◽  
Case Report ◽  
Contact Dermatitis ◽  
Dermatitis Herpetiformis ◽  
Therapeutic Option ◽  
Direct Immunofluorescence ◽  
Gluten Free ◽  
Review Of The Literature ◽  
The Face ◽  
Allergic Contact

Dermatitis herpetiformis is a cutaneous manifestation of celiac disease that classically presents as a symmetric pruritic vesicular eruption on extensor surfaces. Typical locations include elbows, knees, and buttocks. Facial involvement has been reported rarely. Here, we report a case of a 44-year-old woman with dermatitis herpetiformis presenting as pruritic vesicles on the face that had previously been misdiagnosed as allergic contact dermatitis. Diagnosis was confirmed with direct immunofluorescence demonstrating granular IgA in the papillary dermis. This eruption cleared with topical dapsone 5% gel and a gluten-free diet. We report this case to raise awareness of facial involvement in dermatitis herpetiformis as well as the possibility of topical dapsone as a therapeutic option.

An unique case of celiac disease with hypocoagulation and secondary hyperparathyreodism in elderly patient - a case report

2017 ◽  
Author(s):  
Gocha Barbakadze ◽  
Lali Tigishvili ◽  
Levan Ramishvili ◽  
Nani Tsikarishvili ◽  
Koba Burnadze
Keyword(s):  
Elderly Patient ◽  
Celiac Disease ◽  
Case Report ◽  
Unique Case

scholarly journals Case Report: Papillary Thyroid Cancer in a Patient with Celiac Disease and Thalassemia Trait

2020 ◽  
Vol 13 (3) ◽  
pp. 1364-1367
Author(s):  
Afaf Albattah ◽  
Yahia Imam ◽  
Ahmed Osman Saleh ◽  
Khalid Ahmed ◽  
Tarek Aboursheid ◽  
...  
Keyword(s):  
Risk Factors ◽  
Thyroid Cancer ◽  
Celiac Disease ◽  
Case Report ◽  
Papillary Thyroid Cancer ◽  
Thalassemia Major ◽  
Papillary Thyroid ◽  
Unique Case ◽  
Thalassemia Trait ◽  
Common Risk Factors

Thyroid cancer is the most frequent endocrine neoplasm in the general population. Common risk factors include gender, radiation exposure, and genetic backgrounds. The association of papillary thyroid cancer and celiac disease has frequently been reported in the literature; however, the association of papillary thyroid cancer and thalassemia trait is rare. Likewise, the association of thalassemia major and celiac disease is also rare. We hereby report a unique case of papillary thyroid cancer in a patient with celiac disease and thalassemia trait.

scholarly journals Esophagitis Dissecans Superficialis (EDS) Secondary to Hair Dye Ingestion: Case Report and Literature Review

2021 ◽  
Vol 11 (2) ◽  
pp. 185-189
Author(s):  
Eric Omar Then ◽  
Tyler Grantham ◽  
Michell Lopez ◽  
Madhavi Reddy ◽  
Vinaya Gaduputi
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Autoimmune Disorders ◽  
Pharmacologic Therapy ◽  
Esophageal Mucosa ◽  
Hair Dye ◽  
Esophageal Lesion ◽  
Chemical Irritants

Esophagitis dissecans superficialis (EDS) is a rare and underdiagnosed esophageal lesion characterized by sloughing of the esophageal mucosa that has been associated with medications, various autoimmune disorders, and exposure to some chemical irritants. Anatomically, EDS is most commonly seen in the middle and distal thirds of the esophagus. When present, EDS is best treated by discontinuing the offending agent and initiating pharmacologic therapy with proton pump inhibitors. Steroids may also be effective if the etiology is autoimmune in nature. Our case highlights a 65-year-old female diagnosed with EDS after incidental ingestion of hair dye containing resorcinol and para-phenylenediamine (PPD).

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