scholarly journals Study of hypoglycemia in neonates with low birth weight

2020 ◽  
Vol 7 (8) ◽  
pp. 409-413
Author(s):  
Dr. Ekta Acharya ◽  

Background and Aim: The maintenance of normoglycemia in newborns depends upon theadequacy of glycogen stores, maturation of glycogenolytic and gluconeogenic pathways, andintegrated endocrine response. The current study, therefore, proposes to observe the clinical profileof low-birth-weight babies concerning the occurrence of hypoglycemia. Materials and Methods:The neonates with a weight of fewer than 2500 grams were included in the study. A total of 100infants were included in the study. They were divided into two groups with infants withhypoglycemia in one group and infants with normoglycemic in another group. The aseptic conditionwas maintained and with the help of heel prick, the capillary blood was collected. The capillary bloodwas screened with the help of reagent strips. Results: Out of the total 100 neonates, a total of 76neonates were normoglycemic and 24 neonates had hypoglycaemic episodes. Overall 22 episodes ofhypoglycemia were recorded. There was no significant association between birth weight andepisodes of hypoglycemia. The majority of hypoglycaemic infants were male. Conclusion:Hypoglycemia associated with abnormal clinical signs (symptomatic hypoglycemia) has a poor short-and long-term outcome but evidence of risk in the absence of clinical signs (asymptomatichypoglycemia) is inconclusive. Small for gestational age is a significant determinant forhypoglycemia. Hypoglycaemic episodes were significantly noticed in the first 24 hours as comparedto another time interval.

KYAMC Journal ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 77-82
Author(s):  
Mosammat Afroza Jinnat ◽  
Shafi Ahmed ◽  
Sirajum Monira ◽  
Muhammad Mozammel Haque ◽  
Mashura Musharraf ◽  
...  

Background: Preterm Low Birth Weight babies carry relatively higher risk of perinatal and neonatal mortality, retarded growth and development subsequently. In this study, some maternal risk factors were investigated as it seems to be important to study these factors on regional basis. Objective: To find out the maternal risk factors, clinical profile and short term outcome of pre-term low birth weight neonates by gestational age, birth weight, Occipitofrontal Circumference, length, different presentation (asphyxia, hypothermia, feeding difficulties, signs of infection) on admission and the morbidity and mortality of preterm LBW. Materials and Methods: A descriptive type of cross sectional study was done in neonatal ward of Jalalabad Ragib Rabeya Medical College Hospital, Sylhet from May, 2015 to April, 2016. Hundred cases were selected from neonatal ward and 100 controls were selected from obstetrics ward. Results: Among 100 pre-term LBW neonates, 52 were male and 48 were female. Only 22% mother took regular antenatal check up in case group and 55% in control group. Mean gestational age of neonates were 33.3±2.1 weeks. Important risk factors were primi parity (58% in cases vs 34% in control), hypertension (19% vs 5%), pre-eclampsia (26% vs 12%), prolonged rupture of membrane (33% vs 7%), APH (22% vs 0%), acute infection (8% vs 1%), multiple birth (17% vs 2%). Common clinical presentations were prematurity and LBW. Commonest morbidity was feeding problem (70%). The overall survival rate was 87%. Most common cause of death was septicemia (30%). Conclusion: all the identified risk factors were significantly higher in pre-term LBW babies than those of control. KYAMC Journal Vol. 11, No.-2, July 2020, Page 77-82


2013 ◽  
Vol 82 (5) ◽  
pp. 802-810 ◽  
Author(s):  
Daisuke Kobayashi ◽  
Salaam Sallaam ◽  
Sanjeev Aggarwal ◽  
Harinder R. Singh ◽  
Daniel R. Turner ◽  
...  

1989 ◽  
Vol 160 (3) ◽  
pp. 539-545 ◽  
Author(s):  
Lula O. Lubchenco ◽  
L. Joseph Butterfield ◽  
Virginia Delaney-Black ◽  
Edward Goldson ◽  
Beverly L. Koops ◽  
...  

2007 ◽  
Vol 20 (6) ◽  
pp. 465-471 ◽  
Author(s):  
A. Valcamonico ◽  
P. Accorsi ◽  
C. Sanzeni ◽  
P. Martelli ◽  
P. La Boria ◽  
...  

Author(s):  
Ruya Çolak ◽  
Senem Alkan Ozdemir ◽  
Ezgi Yangin Ergon ◽  
Ferit Kulali ◽  
Oguz Han Kalkanli ◽  
...  

Objective: Hemodynamically significant patent ductus arteriosus(hsPDA) is resulting in severe mortality and morbidity in infants with extremely low birth weight(ELBW). In our study, we aimed to evaluate the necessity of performing routine echocardiography(ECHO) in the first 72hours in ELBW infants.Study Design:This study was planned retrospectively and observationally.Between June2016 and December2018,36 patients diagnosed with hemodynamically significant PDA(hsPDA) who were hospitalized in the neonatal intensive care unit(NICU),with ≤28Gw or ≤1000g were included in this study.These babies were routinely performed ECHO for PDA between 24-72hours,although they were asymptomatic in the period from June2016 to December2017(n:23).Between January2018 and December2018, patients without PDA symptoms were expected to complete 72hours for routine PDA screening (n:13).The patients were divided into 2 groups as early ECHO group(EEG)(n=23) and late ECHO group (LEG)(n=13).In the presence of at least one of the clinical signs of systemic hypoperfusion and/or pulmonary hyperperfusion, symptomatic PDA was accepted and closure treatment was  applied with ibuprofen(n: 23) or paracetamol(n: 5).While the two groups were compared in terms of demographic features,ECHO findings,and the state of taking closure therapy,patients receiving closure therapy were compared in terms of mortality and premature morbidity.Results:The average birth weight of 36 patients was 855.9(± 241.5)g, and the average week of birth was 26.4(± 2.1)Gw.It was observed that the two groups were similar in terms of demographic characteristics.Although the findings of ECHO and treatment rates were similar between the two groups,it was observed that the EEG had earlier closure treatment(p = 0.03). In patients receiving closure treatment, performing early(n:17)and late(n:11) echocardiography showed no statistical difference in the long-term results.Conclusion:Performing early ECHO without symptoms in infants with ELBW may provoke the clinician to give PDA closure treatment earlier. In infants with ELBW,unnecessary closure treatment can be prevented by closely monitoring the symptoms of PDA and performing ECHO when necessary.


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