Methodology for determining the anthrofundal border of the stomach in the surgical treatment of peptic ulcer disease

1986 ◽  
Vol 67 (6) ◽  
pp. 405-407
Author(s):  
V. F. Naumov ◽  
V. Ya. Popov
Keyword(s):  
Peptic Ulcer ◽  
Surgical Treatment ◽  
Peptic Ulcer Disease ◽  
Mucous Membrane ◽  
Distal Part ◽  
The Body ◽  
Selective Proximal Vagotomy ◽  
Gastric Stump ◽  
Ulcer Disease ◽  
The Right

Special methods allowing during the operation to establish the boundary between the mucous membrane of the body and the antral part of the stomach have an important practical value. Knowledge of gastric secretory topography provides clear performance of organ-saving operations (antrumectomy and selective proximal vagotomy). We propose to "cut out" the gastric stump so that it retains a part of the vagal nerve branches (in the area of cardia, esophagus, along the right gastroesophageal artery) and in its distal part it is represented by the antral part of the stomach.

Surgical Treatment of Peptic Ulcer Disease

2017 ◽  
pp. 53-64
Author(s):  
Marcin Włodarczyk ◽  
Paweł Siwiński ◽  
Aleksandra Sobolewska-Włodarczyk
Keyword(s):  
Peptic Ulcer ◽  
Surgical Treatment ◽  
Peptic Ulcer Disease ◽  
Ulcer Disease

The Role of Gastric Acid in Preventing Foodborne Disease and How Bacteria Overcome Acid Conditions†

2003 ◽  
Vol 66 (7) ◽  
pp. 1292-1303 ◽  
Author(s):  
JAMES L. SMITH
Keyword(s):  
Peptic Ulcer ◽  
Acid Secretion ◽  
Peptic Ulcer Disease ◽  
Gastric Acid Secretion ◽  
Gastric Acid ◽  
Gastric Fluid ◽  
The Body ◽  
Peptic Ulcers ◽  
Ulcer Disease ◽  
H Pylori

The secretion of hydrochloric acid by the stomach plays an important role in protecting the body against pathogens ingested with food or water. A gastric fluid pH of 1 to 2 is deleterious to many microbial pathogens; however, the neutralization of gastric acid by antacids or the inhibition of acid secretion by various drugs may increase the risk of food- or waterborne illnesses. Peptic ulcer disease is often treated by decreasing or eliminating gastric acid secretion, and such treatment blocks the protective antibacterial action of gastric fluid. The majority of peptic ulcer disease cases originate from Helicobacter pylori infections. Treatment of H. pylori–induced peptic ulcers with antibiotics reduces the need for drugs that inhibit gastric acid secretion and thereby diminishes the risk of food- and waterborne illness for peptic ulcer disease patients. Many bacterial pathogens, such as Escherichia coli, Salmonella Typhimurium, and H. pylori, can circumvent the acid conditions of the stomach by developing adaptive mechanisms that allow these bacteria to survive in acid environments. As a consequence, these bacteria can survive acidic stomach conditions and pass into the intestinal tract, where they can induce gastroenteritis.

THE STATE AND ROLE OF ESOPHAGUS, STOMACH, INTESTINAL MICROBIOTA IN PATIENTS WITH ULCER DISEASE, CHRONIC GASTRITIS, ESOPHAGITIS

2020 ◽  
Vol 65 (1) ◽  
pp. 42-49
Author(s):  
V. M. Chervinets ◽  
A. Yu. Mironov ◽  
Yu. V. Chervinets ◽  
S. N. Bazlov
Keyword(s):  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Mucous Membrane ◽  
Chronic Gastritis ◽  
Low Frequency ◽  
Duodenal Mucosa ◽  
Pathological Process ◽  
Quantitative Composition ◽  
Ulcer Disease ◽  
Opportunistic Bacteria

The microflora of 64 biopsies taken during fibrogastroduodenoscopy of the mucous membrane of the esophagus, stomach and duodenum in healthy volunteers and 1120 samples obtained from the same parts of the digestive tract in patients with esophagitis, chronic gastritis and peptic ulcer disease were studied. The patients ranged in age from 18 to 62 years. Traditional bacteriological method was used to isolate and identify microorganisms. Staphylococcus spp., Streptococcus spp., Lactobacillus spp., Bacteroides spp., Stomatococcus spp., Enterobacteriaceae, Corynebacterium spp., Micrococcus spp., Neisseria spp., Veilonella spp. were isolated from biopsies of healthy respondents in an average amount from 3.2 to 4.68 lg CFU/g. H.pylori was found in 60% (5.66 lg CFU/g) in the esophagus, in 33.3% of cases (5.12 lg CFU/g) from the fundal part of the stomach, in 44.4% (5.25 lg CFU/g) from the antral part of the stomach, in 5.5% (4.2 lg CFU/g) in the duodenal mucosa. In samples obtained from the inflamed and eroded mucous membrane of the esophagus, stomach and duodenum, opportunistic bacteria of the genera Klebsiella, Enterobacter, Proteus, Pseudomonas, Peptococcus, Actinomyces, yeast fungi of the genus Candida etc. were detected in an amount exceeding 4 lg CFU/g. H. pylori isolated in 6.3-16.7% of patients (4.25-4.6 lg CFU/g) and did not dominate in relation to other microorganisms, and in most cases had a low frequency of its occurrence. In patients with the recurrence of peptic ulcer disease, exacerbation of chronic gastritis and esophagitis, dysbiosis was developed, characterized by an increase in the species and quantitative composition of opportunistic microflora, an increase in its enzymatic and cytotoxic activity, which can contribute to the maintenance of inflammatory and necrotic processes and inhibit the elimination of the pathological process.

scholarly journals Autonomic dystonia syndrome in conditions of failure of the Bauhinia valve and after its surgical correction as a possible link in the etiopathogenesis of peptic ulcer disease

2021 ◽  
Vol 4 (5) ◽  
pp. 01-05
Author(s):  
Martynov Vladimir Leonidovich
Keyword(s):  
Nervous System ◽  
Peptic Ulcer ◽  
Autonomic Nervous System ◽  
Peptic Ulcer Disease ◽  
Parasympathetic Nervous System ◽  
The Body ◽  
Surgical Correction ◽  
Ulcer Disease ◽  
Autonomic Nervous

The classic works of I.P. Pavlov shows strong communication mechanisms between the two most important life-supporting systems of the body - the nervous and the digestive. The role of the autonomic nervous system (ANS) in the occurrence of acute gastroduodenal erosions and ulcers has been proven [1]. The flow of sympathetic impulses causes an excessive release of mediators (catecholamines), which leads to disruption of tissue trophism. An important role in ulceration belongs to the parasympathetic nervous system.

scholarly journals Complex pharmacotherapy of peptic ulcer disease taking into account its complications from other parts of the digestive system

2021 ◽  
Vol 43 (6) ◽  
pp. 31-35
Author(s):  
A. Ya. Gubergrits
Keyword(s):  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Digestive System ◽  
The Body ◽  
Great Work ◽  
Ulcer Disease ◽  
Local Process ◽  
Healthcare Practice

The progressive view of domestic clinicians on peptic ulcer disease is well known not as a local process in the stomach or in the duodenum, but as a general disease of the body (M. M. Gubergrits, M. P. Konchalovsky, R. A. Luria, N. D. Strazhesko , M.V. Chernorutsky, etc.). However, despite the great work invested in the study of peptic ulcer disease, much in this problem remains unclear and not specified. In particular, the demands of healthcare practice and the results of existing methods of treating peptic ulcer disease do not meet.

On the history of surgical treatment of peptic ulcer disease

2015 ◽  
Vol 2 (3) ◽  
Author(s):  
P.M. Bogopolsky ◽  
◽  
N.N. Krylov ◽  
D.A. Balalykin ◽  
O.V. Babkin ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Surgical Treatment ◽  
Peptic Ulcer Disease ◽  
Ulcer Disease ◽  
History Of

scholarly journals Prognosis and clinicopathologic features in patients with gastric stump cancer after curative surgery

2020 ◽  
Vol 27 (3) ◽  
Author(s):  
C. Y. Kung ◽  
W. L. Fang ◽  
R. F. Wang ◽  
C. A. Liu ◽  
A. F. Y. Li ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Peptic Ulcer ◽  
Lymph Node ◽  
Peptic Ulcer Disease ◽  
Gastric Surgery ◽  
Gastric Stump ◽  
Clinicopathologic Characteristics ◽  
Gastric Stump Cancer ◽  
Ulcer Disease ◽  
Primary Gastric Cancer

Background Gastric stump (“remnant”) cancer is the development of a malignancy related to previous gastric surgery. Prognosis in gastric stump cancer, compared with that in primary gastric cancer, is still controversial. Methods From January 1988 to December 2012 at a single medical centre in Taiwan, 105 patients with gastric stump cancer, including 85 with previous peptic ulcer disease and 20 with previous gastric cancer, were analyzed for clinicopathologic characteristics and overall survival (os). Results The 5-year os rates for patients with gastric stump cancer and with primary gastric cancer were 51.2% and 54.5% respectively (p = 0.035). Analysis of clinicopathologic characteristics indicated that, compared with patients having primary gastric cancer, those with gastric stump cancer had more lymph node metastasis (p < 0.001) and had been diagnosed at a more advanced stage (p = 0.047). Multivariate analysis with os as an endpoint showed that age [p = 0.015; hazard ratio (hr): 2.300; 95% confidence interval (ci): 1.173 to 4.509], tumour size (p = 0.037; hr: 1.700; 95% ci: 1.031 to 2.801), stromal reaction (p = 0.021; hr: 1.802; 95% ci: 1.094 to 2.969), and pathologic N category (p = 0.001; hr: 1.449; 95% ci: 1.161 to 1.807) were independent predictors in gastric stump cancer. The os rates for patients with gastric stump cancer who previously had gastric cancer or peptic ulcer disease were 72.9% and 50.0% respectively (p = 0.019). The Borrmann classification was more superficial (p = 0.005), lymph node metastases were fewer (p = 0.004), and staging was less advanced (p = 0.025) in patients with gastric stump cancer who previously had gastric cancer than in their counterparts who previously had peptic ulcer disease. Conclusions Survival is poorer in patients with gastric stump cancer who previously had peptic ulcer disease than in those who previously had primary gastric cancer. Patients with gastric stump cancer who previously had gastric cancer and could receive curative gastrectomy tended to have a better prognosis because of a more superficial Borrmann classification. Regular follow-up in patients who have undergone gastric surgery is recommended for the early detection of gastric stump cancer.  

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