Oehme. The action of adrenaline on the function of the thyroid gland (K. Woch., 11 / IV, 1936)

1937 ◽  
Vol 33 (7) ◽  
pp. 933-933
Author(s):  
V. Dembskaya
Keyword(s):  
Thyroid Gland ◽  
Adrenal Cortex ◽  
Guinea Pigs ◽  
Basal Metabolism ◽  
Clinical Forms

The author draws attention to the fact that the extract of the adrenal cortex is inherent in the ability to moderate the activity of the thyroid gland and neutralize the action of thyroxine. By administering adrenaline to guinea pigs with artificially maintained hyperthyroidism, he sought to reduce its manifestations. An increase in basal metabolism from the administration of thyroxine does not occur if the adrenal cortex extract is simultaneously administered. The author also noticed that C-vitamin acid can produce a similar effect. Studying the antithyroid substance of the adrenal cortex, the author noted that it is destroyed after 2-3 hours when oxygen is passed over it at a pH of 93 and a temperature of 38 C. The author believes that the extract of the adrenal cortex can provide valuable services in the fight against clinical forms of hyperthyroidism.

Respiratory Metabolism During Pregnancy in the Guinea Pig

1957 ◽  
Vol 190 (3) ◽  
pp. 425-428 ◽  
Author(s):  
Richard M. Hoar ◽  
William C. Young
Keyword(s):  
Heart Rate ◽  
Oxygen Consumption ◽  
Guinea Pig ◽  
Metabolic Rate ◽  
Adrenal Cortex ◽  
Guinea Pigs ◽  
Sharp Decrease ◽  
Zona Fasciculata ◽  
Respiratory Metabolism ◽  
Morphological Differences

Oxygen consumption and heart rate during pregnancy were measured in untreated, thyroxin-injected and thyroidectomized guinea pigs given I131. From impregnation until parturition, oxygen consumption increased 7.9% in untreated females. The increase continued until 5 days postpartum when a sharp decrease occurred. The increase is not accounted for by growth of the fetal mass. Comparable increases occurred in thyroxin-injected (16.2%) and thyroidectomized (11.9%) females, although the levels throughout were higher and lower, respectively, than in intact females. Heart rate did not increase. On the contrary, statistically significant decreases occurred in the untreated and thyroxin-injected females. Although the mechanism associated with the increased metabolic rate is not known, the possibility of thyroid participation would seem to be excluded. Involvement of the adrenal cortex is suggested by morphological differences in the cells of the zona fasciculata in pregnant and nonpregnant females and by evidence cited from other studies.

scholarly journals Osobennosti funktsional'nogo sostoyaniyakory nadpochechnikov i shchitovidnoy zhelezypri metabolicheskom sindrome

2011 ◽  
Vol 8 (3) ◽  
pp. 46-50 ◽  
Author(s):  
I V Madyanov ◽  
V A Kichigin ◽  
T N Markova ◽  
S M Semakina ◽  
I B Bashkova
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Thyroid Gland ◽  
Systolic Blood Pressure ◽  
Adrenal Cortex ◽  
Functional State ◽  
Thyroid Stimulating Hormone ◽  
Blood Levels ◽  
Dehydroepiandrosterone Sulphate ◽  
Total Triiodothyronine

The aim. To study the functional state of adrenal cortex and thyroid gland in metabolic syndrome (MS). 186 women and 65 men were included. Blood levels of cortisol, dehydroepiandrosterone sulphate, total thyroxin, total triiodothyronine, thyroid stimulating hormone were studied in subjects with and without metabolic syndrome (IDF test) and their relation with MS components. The results. 75 (29,9%) of the 251 examined patients had MS. In the group with MS the levels of total thyroxin and dehydroepiandrosterone sulphate were decreased to 1,90±0,18 microgram/milliliter vs. 2,37±0,12 microgram/milliliter (р=0,033) in patients without MS and 2,19±0,26 nmol/l vs. 2,59±0,15 nmol/l (р=0,040), respectively. The levels of dehydroepiandrosterone sulphate were inversely correlated with the systolic blood pressure (r=-0,23, р

Role of cyclic AMP in the action of dopaminergic D2 receptors of some endocrine glands in rats

1987 ◽  
Vol 7 (10) ◽  
pp. 751-755 ◽  
Author(s):  
Abdulrahim Abu-Jayyab ◽  
Ezz-Eddin S. M. El-Denshary ◽  
Abdulrahman M. Ageel ◽  
Mohamed Rafik Dakkak
Keyword(s):  
Thyroid Gland ◽  
Cyclic Amp ◽  
Adrenal Cortex ◽  
D2 Receptors ◽  
Endocrine Glands ◽  
Long Term Effects ◽  
Short Term ◽  
Presence And Absence

Short-term and long-term effects of bromocriptine mesylate (10 mg/kg i.p.) on cyclic AMP contents of the liver and some endocrine glands have been investigated in the presence and absence of sulpiride (10 mg/kg i.p.). Results revealed that bromocriptine caused significant elevations in the cyclic AMP contents of the liver and reduction in its adrenocortical content. Bromocriptine effect on the adrenal cortex was antagonized by sulpiride, whereas its effect on the liver was not changed. Bromocriptine did not change the, cyclic AMP content in the thyroid gland or the ovary.

Effect of Potassium Iodide on Basal Metabolism in Guinea Pigs

1930 ◽  
Vol 27 (7) ◽  
pp. 629-630 ◽  
Author(s):  
W. J. Siebert ◽  
R. S. Smith
Keyword(s):  
Potassium Iodide ◽  
Guinea Pigs ◽  
Basal Metabolism
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