scholarly journals Intraocular Pressure Fluctuation – Assess in Clinical Practice

2013 ◽  
Vol 07 (01) ◽  
pp. 7
Author(s):  
Marcelo Hatanaka ◽  
Keyword(s):  
Risk Factor ◽  
Intraocular Pressure ◽  
Clinical Practice ◽  
Visual Field ◽  
Main Risk Factor ◽  
Standard Definition ◽  
Glaucoma Treatment ◽  
Definition Of ◽  
The Impact ◽  
Intraocular Pressure Fluctuation

Intraocular pressure (IOP) is the main risk factor for the development and progression of glaucoma. Treatment is based on IOP reduction and isolated tonometric readings are usually performed for clinical management of the disease. However, IOP is not a static parameter and varies considerably throughout the day. This variability, or fluctuation, has classically been considered a risk factor for glaucoma. Nevertheless, recent studies demonstrate that pressure peaks are the most relevant IOP parameter for the prediction of visual field progression. The lack of a standard definition of IOP fluctuation compromises its clinical assessment and may explain in part the contradictory results found in the literature. This review will analyse options for IOP fluctuation assessment, their limitations and the impact of this parameter on the management of glaucoma.

scholarly journals Detecting IOP Fluctuations in Glaucoma Patients

2016 ◽  
Vol 10 (1) ◽  
pp. 44-55 ◽  
Author(s):  
Brenda Nuyen ◽  
Kaweh Mansouri
Keyword(s):  
Risk Factor ◽  
Intraocular Pressure ◽  
Clinical Practice ◽  
Vision Loss ◽  
Measurement Techniques ◽  
Dynamic Parameter ◽  
Guiding Principle ◽  
Informative Parameters ◽  
Technological Advances ◽  
Glaucoma Treatment

Lowering intraocular pressure (IOP) remains the guiding principle of glaucoma management. Although IOP is the only treatable risk factor, its 24-hour behavior is poorly understood. Current glaucoma management usually relies on single IOP measurements during clinic hours, even though IOP is a dynamic parameter with rhythms dependent on individual patients. It has further been shown that most glaucoma patients have their highest IOP measurements outside clinic hours. The fact that these IOP peaks go largely undetected may explain why certain patients progress in their disease despite treatment. Nevertheless, single IOP measurements have determined all major clinical guidelines regarding glaucoma treatment. Other potentially informative parameters, such as fluctuations in IOP and peak IOP, have been neglected, and effects of IOP-lowering interventions on such measures are largely unknown. Continuous 24-hour IOP monitoring has been an interest for more than 50 years, but only recent technological advances have provided clinicians with a device for such an endeavor. This review discusses current uses and shortcomings of current measurement techniques, and provides an overview on current and future methods for 24-hour IOP assessment. It may be possible to incorporate continuous IOP monitoring into clinical practice, potentially to reduce glaucoma-related vision loss.

scholarly journals Investigation of intraocular pressure fluctuation as a risk factor of glaucoma progression

2018 ◽  
Vol Volume 13 ◽  
pp. 9-16 ◽  
Author(s):  
Juliane Matlach ◽  
Sandra Bender ◽  
Jochem König ◽  
Harald Binder ◽  
Norbert Pfeiffer ◽  
...  
Keyword(s):  
Risk Factor ◽  
Intraocular Pressure ◽  
Pressure Fluctuation ◽  
Glaucoma Progression ◽  
Intraocular Pressure Fluctuation

scholarly journals Impact of Visual Field Testing on Intraocular Pressure Change Trends in Healthy People and Glaucoma Patients

2020 ◽  
Vol 2020 ◽  
pp. 1-6 ◽  
Author(s):  
Mengwei Li ◽  
Bingxin Zheng ◽  
Qi Wang ◽  
Xinghuai Sun
Keyword(s):  
Intraocular Pressure ◽  
Visual Field ◽  
Repeated Measures ◽  
Healthy Subjects ◽  
Open Angle Glaucoma ◽  
Field Testing ◽  
Automated Perimetry ◽  
Open Angle ◽  
Standard Automated Perimetry ◽  
The Impact

Purpose. To compare the impact of visual field (VF) testing on intraocular pressure (IOP) change trends between healthy subjects and glaucoma patients. Methods. We recruited healthy volunteer subjects who did not have previous ocular diseases and open-angle glaucoma patients who were medically controlled well. IOP in both eyes of each participant was measured by using a noncontact tonometer at five time points: before, immediately after (0 minute), and 10, 30, and 60 minutes after the standard automated perimetry. Repeated measures ANOVA was used to analyze the effect of VF testing on IOP change trends in healthy and glaucoma eyes. Results. Forty healthy subjects (80 eyes) and 31 open-angle glaucoma patients (62 eyes) were included for the study. The baseline IOP of healthy and glaucoma eyes was 16.11 ± 3.01 mmHg and 15.78 ± 3.57 mmHg, respectively. After the VF testing, the IOP in healthy eyes was decreased by 1.5% at 0 minute, 6.5% at 10 minutes (P<0.001), 6.6% at 30 minutes (P<0.001), and 7.0% at 1 hour (P<0.001), indicating that this reduction was sustained for at least 1 hour. However, the IOP in glaucoma eyes was increased by 12.7% at 0 minute (P<0.001) and, then, returned towards initial values 1 hour after the VF testing. Conclusions. IOP change trends after VF field testing between healthy subjects and glaucoma patients were quite different. VF testing led to a mild and relatively sustained IOP decrease in healthy subjects, whereas IOP in open-angle glaucoma patients tended to significantly increase immediately after VF testing and, then, returned to pretest values after 1 hour. These findings indicate that the factors of VF testing should be considered in the clinical IOP measurements.

Intraocular pressure as a risk factor for visual field loss in pseudoexfoliative and in primary open-angle glaucoma

Ophthalmology ◽  
1998 ◽  
Vol 105 (12) ◽  
pp. 2225-2230 ◽  
Author(s):  
Miguel A Teus ◽  
Miguel A Castejón ◽  
Miguel A Calvo ◽  
Patricia Pérez—Salaı́ces ◽  
Ana Marcos
Keyword(s):  
Risk Factor ◽  
Intraocular Pressure ◽  
Visual Field ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Visual Field Loss ◽  
Open Angle

scholarly journals The Impact of Surgical Intraocular Pressure Reduction on Visual Function Using Various Criteria to Define Visual Field Progression

2013 ◽  
Vol 22 (8) ◽  
pp. 632-637 ◽  
Author(s):  
Namita Bhardwaj ◽  
Philip I. Niles ◽  
David S. Greenfield ◽  
Maggie Hymowitz ◽  
Mitra Sehi ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Visual Field ◽  
Visual Function ◽  
Pressure Reduction ◽  
Visual Field Progression ◽  
Intraocular Pressure Reduction ◽  
The Impact

Latanoprost for Open-Angle Glaucoma

2020 ◽  
pp. 97-102
Author(s):  
Alan D. Penman ◽  
Kimberly W. Crowder ◽  
William M. Watkins
Keyword(s):  
United Kingdom ◽  
Intraocular Pressure ◽  
Visual Field ◽  
Open Angle Glaucoma ◽  
Controlled Trial ◽  
Prostaglandin Analogue ◽  
Open Angle ◽  
Topical Drugs ◽  
The United Kingdom ◽  
Glaucoma Treatment

The United Kingdom Glaucoma Treatment Study (UKGTS) was a randomized, triple-masked, placebo-controlled trial comparing topical latanoprost, a prostaglandin analogue, with placebo in patients with newly diagnosed, previously untreated open-angle glaucoma (OAG). Compared to placebo, the latanoprost group showed a large, statistically significant reduction in the rate of glaucomatous visual field deterioration by 24 months. The UKGTS was the first placebo-controlled trial to show visual field preservation through lowering of intraocular pressure with topical drugs in patients with OAG, and the first to show the visual field–preserving effect of a topical prostaglandin analogue.

Intraocular Pressure Control and Long-Term Visual Field Loss in Open-Angle Glaucoma

2020 ◽  
pp. 91-96
Author(s):  
Alan D. Penman ◽  
Kimberly W. Crowder ◽  
William M. Watkins
Keyword(s):  
Intraocular Pressure ◽  
Visual Field ◽  
Open Angle Glaucoma ◽  
Visual Field Loss ◽  
Pressure Control ◽  
Open Angle ◽  
Aggressive Treatment ◽  
Visual Field Progression ◽  
Glaucoma Treatment

The Collaborative Initial Glaucoma Treatment Study (CIGTS) was a randomized clinical trial to determine whether patients with newly diagnosed open-angle glaucoma (OAG) were managed better by initial treatment with medications (using a stepped regimen of medications starting initially with a topical beta-blocker) or by immediate filtration surgery (trabeculectomy with or without 5-fluorouracil). Although the surgery group achieved a lower mean intraocular pressure (IOP) than the medication group, both groups had similarly low rates of visual field progression. Three measures of IOP fluctuation over extended time, the range of IOP, the standard deviation of IOP, and the maximum IOP, seem to play an important role in visual field progression The results showed that more aggressive treatment was warranted when undue elevation or variation in IOP measures is observed.

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