scholarly journals Struma Ovarii associated with Pseudo-Meigs Syndrome and elevated serum Ca 125: Case report and literature review

2017 ◽  
Vol 7 (1) ◽  
pp. 336
Author(s):  
Oyuki A. Morales ◽  
Junior J. Araiza ◽  
Tania P. Alvarez Dominguez ◽  
Rafael Medrano Guzmán ◽  
Jorge A. Barbabosa ◽  
...  
Keyword(s):  
Case Report ◽  
Pleural Effusion ◽  
Thyroid Tissue ◽  
Elevated Serum ◽  
Rare Condition ◽  
Definitive Diagnosis ◽  
Ca 125 ◽  
Struma Ovarii ◽  
Axial Tomography ◽  
Diagnostic Characteristics

Struma Ovarii is a highly specialized monodermal teratoma in which the major component is thyroid tissue. Its relationship with Pseudo Meigs syndrome, hyperthyroidism and elevation of Ca 125 is a rare condition; this could mimic malignancy. Ultrasound and axial tomography may be useful in diagnosis; but histopathological criteria play a very important role in the definitive diagnosis. Our objective is to present a case report of Struma ovarii, ascites, pleural effusion (pseudo meigs syndrome), elevation of Ca 125, hyperthyroidism, and review the published literature in relation to epidemiology and diagnostic characteristics.

scholarly journals Meigs' syndrome with elevated CA 125: case report

2003 ◽  
Vol 121 (5) ◽  
pp. 210-212 ◽  
Author(s):  
Sabas Carlos Vieira ◽  
Leonardo Halley Carvalho Pimentel ◽  
José Carlos Castelo Branco Ribeiro ◽  
Argemiro Ferreira de Andrade Neto ◽  
Jerúsia Oliveira Ibiapina de Santana
Keyword(s):  
Case Report ◽  
Pleural Effusion ◽  
Ovarian Tumor ◽  
Frozen Section ◽  
Transvaginal Ultrasound ◽  
Elevated Serum ◽  
Ca 125 ◽  
Brazilian Woman ◽  
Thoracic Drainage ◽  
Benign Ovarian Tumor

CONTEXT: Meigs' syndrome consists of a benign ovarian tumor accompanied by ascites and hydrothorax. Elevated serum CA 125 levels in postmenopausal women with solid adnexal masses, ascites and pleural effusion are highly suggestive for malignant ovarian tumor. However, patients with Meigs' syndrome can also have elevated serum CA 125 levels. The authors report a case of Meigs' syndrome with elevated CA 125 level. OBJECTIVE: This is a case report of Meigs' syndrome with elevated CA 125 level. CASE REPORT: A 65-year-old Brazilian woman had presented progressive dyspnea, weight loss and decline in general condition over the 7 months preceding admission to our service. In another hospital, the patient had been submitted to thoracic drainage due to pleural effusion. With recurrence of the pleural effusion and increase in abdominal volume due to ascites and a pelvic mass, the patient sought our service. Transvaginal ultrasound showed an extensive adnexal solid mass of 16.4 x 10.8 cm located in the pelvis without exact limits, and the serum CA 125 level was elevated. With a preoperative diagnosis of ovarian carcinoma, the patient was submitted to exploratory laparotomy, which revealed a left ovarian tumor. The frozen section diagnosis was thecoma. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed. The histology of the specimen confirmed the diagnosis of thecoma. The patient was asymptomatic with a normal serum CA 125 level 20 months after the operation.

scholarly journals Coexistence of benign struma ovarii, pseudo-Meigs’ syndrome and elevated serum CA 125: Case report and review of the literature

2015 ◽  
Vol 9 (4) ◽  
pp. 1739-1742 ◽  
Author(s):  
CHENGJUAN JIN ◽  
RUIYING DONG ◽  
HUALEI BU ◽  
MINGYUAN YUAN ◽  
YOUZHONG ZHANG ◽  
...  
Keyword(s):  
Case Report ◽  
Elevated Serum ◽  
Ca 125 ◽  
Struma Ovarii ◽  
Review Of The Literature

scholarly journals Struma ovarii associated with pseudo-Meigs' syndrome and elevated serum CA 125: a case report and review of the literature

2010 ◽  
Vol 3 (1) ◽  
pp. 18 ◽  
Author(s):  
Wei Jiang ◽  
Xin Lu ◽  
Zhi Ling Zhu ◽  
Xi Shi Liu ◽  
Cong Jian Xu
Keyword(s):  
Case Report ◽  
Elevated Serum ◽  
Ca 125 ◽  
Struma Ovarii ◽  
Review Of The Literature

scholarly journals Bilateral Ovarian Fibrothecoma Associated with Ascites, Bilateral Pleural Effusion, and Marked Elevated Serum CA-125

2013 ◽  
Vol 2013 ◽  
pp. 1-5
Author(s):  
Védi André Serges Loué ◽  
Eléonore Gbary ◽  
Sylvanus Koui ◽  
Bédi Akpa ◽  
Adélaide Kouassi
Keyword(s):  
Ovarian Cancer ◽  
Pleural Effusion ◽  
Tumor Marker ◽  
Tumor Resection ◽  
Elevated Serum ◽  
Rare Condition ◽  
Bilateral Pleural Effusion ◽  
Ca 125 ◽  
African Woman ◽  
Elevated Tumor Marker

Background. The risk of ovarian cancer is increased in the association of ovarian tumor, ascites, and hydrothorax with the significant elevated tumor marker CA-125. However, this association can be observed in a rare clinical and benign pathological entity, that is Demons-Meigs’ syndrome.Objective. To describe a rare case of Demons-Meigs' syndrome observed in our department.Methods. A black African woman of 35 years old, seventh gravida and fourth parous, underwent a total abdominal hysterectomy with bilateral salpingoophorectomy for large bilateral ovarian masses associated with significant ascites, bilateral pleural effusion, and particular highly elevated tumor marker CA-125 (1835 UI/mL) in a pronounced general alteration condition.Results. The postoperative course was uneventful characterized by a complete remission of hydrothorax and ascites with normal level of CA-125 three months after tumor excision. Histology of both masses revealed a bilateral ovarian fibrothecoma, a benign tumor of the ovary, thus confirming the diagnosis of Demons-Meigs’ syndrome.Conclusion. The Demons-Meigs syndrome, although it strongly mimics the clinical picture of malignant metastatic ovarian cancer, remains a disease with benign prognosis after surgical tumor resection. This is a rare condition that must be known and recognized by practitioners to avoid unnecessary practices.

scholarly journals A case report on Meigs’ syndrome and elevated serum CA-125: A rare case report

2021 ◽  
Vol 5 (1) ◽  
pp. 031-033
Author(s):  
Khanduja Divya ◽  
Kajal NC
Keyword(s):  
Case Report ◽  
Pleural Effusion ◽  
Elevated Serum ◽  
Pelvic Mass ◽  
Complete Resection ◽  
Ca 125 ◽  
Shortness Of Breath ◽  
Uncommon Presentation ◽  
Rare Case Report ◽  
Ovarian Neoplasia

Meigs syndrome is an uncommon presentation, where a benign ovarian neoplasia presents along with ascites and pleural effusion. About 1% of ovarian neoplasia can present as Meigs syndrome. Patients with Meigs’ syndrome and elevated serum CA-125 are not frequently reported. We report a case of a 50-year-old women who presented with shortness of breath, cough, weight loss of one and half month duration. Chest radiograph of the patient with clinical examination of patient confirms pleural effusion as cause of progressive shortness of breath. The presence of a pelvic mass and elevated serum CA-125, which raised the possibility of malignancy. After complete resection of tumor, the pathologic reports confirmed a benign ovarian neoplasia. We highlight the importance of suspicion, careful general examination, radiological assessment and histological tests to confirm the diagnosis of Meigs’ syndrome.

Cystic struma ovarii, a rare form of ovarian tumor – a case report, and review of the literature

2007 ◽  
Vol 148 (48) ◽  
pp. 2285-2287 ◽  
Author(s):  
Gabriella Östör ◽  
Ildikó Tóth ◽  
Zsuzsanna Hrubyné Tóth ◽  
Sándor Bazsa
Keyword(s):  
Case Report ◽  
Ovarian Tumor ◽  
Ca 125 ◽  
Struma Ovarii ◽  
Review Of The Literature ◽  
Rare Form

Az ovarialis strumák a petefészek-teratomák kevesebb mint 3%-át adják. Megjelenhet bennük a pajzsmirigy szinte minden betegsége, és előfordulhat malignitás is. A szerzők esetében egy 31 éves nő bal oldali petefészekcisztáját távolították el, amely az ovariumcarcinoma klinikai tüneteit mutatta, úgymint nagy hasi térfoglalás, ascites, emelkedett szérum-CA 125-szint. A szövettani diagnózis benignus struma ovarii volt. A posztoperatív pajzsmirigyműködés normális maradt.

Malignant Clinical Course of Histologically Benign Ovarian Struma: case report and literature review

2021 ◽  
Author(s):  
Aleksandra Asaturova ◽  
A. Magnaeva ◽  
A. Tregubova ◽  
V. Kometova ◽  
E. Karamurzin ◽  
...  
Keyword(s):  
Case Report ◽  
Ovarian Tumor ◽  
Clinical Course ◽  
Mature Teratoma ◽  
Thyroid Tissue ◽  
Follicular Carcinoma ◽  
Struma Ovarii ◽  
Diagnostic Challenge ◽  
Laboratory Findings ◽  
Metastatic Lesions

Abstract BackgroundStruma ovarii is a variant of monodermal teratoma, consisting of morphologically benign, atypical, or frankly malignant thyroid tissue. Morphologic features may or may not correlate with biologic behavior. Albeit this case report is not unique, ovarian tumor developed with peritoneal dissemination and bone metastasis, which is highly unlikely clinical complication. Additionally, we summarized previously cases of struma ovarii with an emphasis on correlation between morphological appearances, clinical course and providing treatment. Case presentationWe present the 38-year-old patient who was hospitalized for ovarian tumor. The diagnostic laparoscopy revealed lesions of peritoneum, sigmoid serosa and omentum and left ovarian mass. We diagnosed left ovarian mature teratoma without struma tissue and metastatic lesions with struma morphology which can be related to her history of left ovarian struma in 2016. Taking into account the metastatic lesions revealed in 2020, the tumor removed in 2016 was assessed as highly differentiated follicular carcinoma arising in struma ovarii. ConclusionsPrediction of biologic behavior of struma ovarii is still to be to diagnostic challenge, therefore multidisciplinary approach including clinical a n d laboratory findings, radiologic details and histopathological features is required. Providing additional data, the present case report contributes to expending the knowledge of these peculiar neoplasms.

Peritoneal tuberculosis with elevated serum CA 125 levels: A case report

1987 ◽  
Vol 28 (3) ◽  
pp. 342-344 ◽  
Author(s):  
Toshihiro Yoshimura ◽  
Hitoshi Okamura
Keyword(s):  
Case Report ◽  
Elevated Serum ◽  
Ca 125 ◽  
Peritoneal Tuberculosis
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