scholarly journals A comparative study of vaginal misoprostol, dinoprostone gel, foley catheter, extra amniotic saline infusion along with vaginal misoprostol for induction of labor at term

2020 ◽  
Vol 9 (9) ◽  
pp. 3683
Author(s):  
Ektha M. Shetty ◽  
Asha Neravi
Keyword(s):  
Cesarean Section ◽  
Vaginal Delivery ◽  
Foley Catheter ◽  
Induction Of Labor ◽  
Saline Infusion ◽  
Bishop Score ◽  
Number Of Patients ◽  
Misoprostol Group ◽  
Nicu Admission ◽  
Vaginal Misoprostol

Background: Objective of this study was to study the effect of vaginal misoprostol, dinoprostone gel, foley catheter, extra amniotic saline infusion along with vaginal misoprostol for induction of labor at term on maternal and fetal outcome.Methods: A one-year prospective observational study was conducted in the department of obstetrics and gynecology, SDM College of Medical Science and Hospital, Dharwad. Totally 100 postdated primigravida women with singleton gestation, vertex presentation and intact membrane who were induced with any four methods of induction 1) Tab. misoprostol 25 µg vaginally, 2) Intracervical dinoprostone gel, 3) Foley catheter and 4) Extra amniotic saline infusion along with tab. misoprostol 25 µg vaginally with 25 patients selected in each group, by random allocation technique and included in the study. Outcome measures analysed were the demographic profile, bishop score, induction to delivery interval, mode of delivery, maternal and fetal complications. Statistical analysis was done using SPSS 17 software.Results: Mean induction delivery interval was significant between PGE1 versus foley group (p=0.0034). In this study, 60% patients in dinoprostone group had Vaginal delivery and 72% in the EASI + misoprostol group underwent cesarean section (p=0.0372). NICU admission was maximum with EASI + vaginal misoprostol group and minimum with vaginal misoprostol alone.Conclusions: The groups were comparable with respect to maternal age, bishop score and fetal weight. The vaginal misoprostol group had shortest induction delivery interval. The maximum number of patients in dinoprostone gel group underwent vaginal delivery with a highest cesarean section and NICU admission with the EASI + misoprostol group.

Combined Use of Vaginal Misoprostol with Intracervical Foley Catheter Versus Vaginal Misoprostol alone in Induction of Labor at Term Pregnancy

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Khaled Hassan Swidan ◽  
Ahmed Abdel Shafy El-Shahawy ◽  
; Ahmed Mohamed Abbass ◽  
Huda Mohamed Elsayed Mohamed
Keyword(s):  
Foley Catheter ◽  
Group Versus ◽  
Maternity Hospital ◽  
Induction Of Labor ◽  
Term Pregnancy ◽  
Number Of Patients ◽  
Misoprostol Group ◽  
Group A ◽  
Vaginal Misoprostol ◽  
Group B

Abstract Background Induction of labor should be used in the most efficient way possible that will result in a favorable obstetric outcome with minimum fetal morbidity. Objectives The aim of this study is to compare the efficacy and safety of intravaginal misoprostol alone versus intra cervical Foley catheter combined with vaginal misoprostol in induction of labor at term pregnancy. Methods This study was conducted at Obstetrics & Gynecology Department; Ain Shams University, Maternity Hospital in the period between May 2017 to October 2017. The total number of patients studied was 120 patients, divided into two groups; the first group (A) included 60 patients who received vaginal misoprostol, the second group (B) included 60 patients who received vaginal misoprostol combined with trans cervical Foley catheter. Results The current study found that the combined group has a better chance for NVD 88.3% versus 78.3% in misoprostol alone group, a lesser probability to CS 11.7% in combined group versus 21.7% in misoprostol alone group and a shorter induction delivery interval within 12 hours after induction (81.6% in combined group versus 59.5% in misoprostol group). Regarding the effect of both methods on fetal safety, we found that non reassuring FHR was more common in combined group 8.3% than misoprostol alone group 1.7% but it’s statistically non-significant. There was statistically significant increase in tachysystole in combined group 28.3% versus 13.3% in misoprostol alone group. However, dystocia was more common in misoprostol group 15% than combined group 3.3% that is also statistically significant. Conclusion Both methods can be used in induction of labor at term pregnancy without forgetting the precautions and close observation to the mother and the fetus. Combined method results in a shorter induction-to delivery time, but misoprostol alone was safer for the mother and the fetus.

scholarly journals A comparative study of 25 mcg vs 50 mcg of vaginal misoprostol for induction of labour

2018 ◽  
Vol 7 (5) ◽  
pp. 1730
Author(s):  
Amika Aggarwal ◽  
Sangeeta Pahwa
Keyword(s):  
Vaginal Delivery ◽  
Mode Of Delivery ◽  
Fetal Outcome ◽  
Induction Of Labor ◽  
Bishop Score ◽  
Uterine Contractions ◽  
Significant Difference ◽  
Misoprostol Group ◽  
Vaginal Misoprostol ◽  
A Prospective Study

Background: The objectives of the current study were to compare the efficacy and safety of 25μg and 50μg of intravaginal misoprostol for induction of labor at term and to study the maternal and fetal outcome.Methods: A Prospective Study was done on 50 cases with 25μg misoprostol and 50 cases of 50μg of misoprostol intravaginal, repeated every 6 hourly till adequate uterine contractions or maximum 5 doses. Total dose of induction, induction delivery interval, mode of delivery, maternal and fetal outcome were recorded.Results: Mean induction delivery interval was 13.8±5.9 and 14.0±5.7 hours (P=0.9) with the 25μg and 50μg misoprostol respectively. The 25μg misoprostol group had a lower delivery rate with a single dose compared with the 50μg group (38% and 42% respectively). However, 25μg group had more deliveries than 50μg group with increasing number of misoprostol doses (36% vs. 38%, and 20% vs. 16% for 2 doses and 3 doses respectively). The need for oxytocin augmentation among participants was higher in the 25μg group (20%) than in 50 μg group (16%).This was however not statistically significant (P=0.603). At lesser initial bishop score, with 50µg misoprostol less doses are needed as compared to 25 µg and hence induction delivery interval decreases. The rates of caesarean section and operative vaginal delivery were similar in both groups. There was no significant difference in maternal side effects and neonatal outcomes among the women in the two groups.Conclusions: The 25 µg of intravaginal misoprostol administered six‑hourly appears to be as effective but safer than 50 µg for induction of labor. The use of 50 µg misoprostol may be recommended when there is a need to expedite vaginal delivery especially in cases of lesser initial bishop score.

scholarly journals Sequential Foley Catheter and Misoprostol Versus Misoprostol Alone for Induction of Labor in Postdated Pregnancy: a Randomized Controlled Trial

2020 ◽  
Vol 3 (1) ◽  
pp. 105-112
Author(s):  
Baburam Dixit Thapa ◽  
Tara Manandhar ◽  
Sarita Sitaula ◽  
Tulasa Basnet
Keyword(s):  
Vaginal Delivery ◽  
Controlled Trial ◽  
Foley Catheter ◽  
Induction Of Labor ◽  
Normal Vaginal Delivery ◽  
Pharmacological Agents ◽  
Sequential Group ◽  
Vaginal Misoprostol ◽  
Foley’S Catheter ◽  
Time To Delivery

Introduction: Induction of labor is done with the aim of normal vaginal delivery. There are different methods; mechanical like intra-cervical Foley’s or pharmacological agents like misoprostol ordinoprostone. Objectives: To compare sequential use of Foley’s catheter and vaginal misoprostol in comparison with vaginal misoprostol only. Methods: Patients with period of gestation more than or equal to 41 weeks without any complications were assigned randomly according to computer generated randomization into sequential use ofintracervical Foley followed by vaginal misoprostol after 24 hours (sequential group) or vaginalmisoprostol only. Primary outcome was rate of normal vaginal delivery. Secondary outcomes were induction to delivery interval, maternal and fetal morbidity. Results: Rate of normal vaginal delivery in sequential group (n= 353) and misoprostol alone group(n= 356) was 71.6% and 53.3% (p < 0.001) but the time to delivery from induction is statistically more in sequential group (30.3 vs. 11.2 hours, p< 0.001). Maternal outcomes like postpartum hemorrhage, hyper-stimulation syndrome, chorioamnitis and neonatal outcomes like low Apgar score, meconium stained baby and stillbirth are similar in both the groups. Conclusions: The priming of cervix using intracervical Foley catheter before giving vaginalmisoprostol was beneficial in increasing the rate of normal vaginal delivery but it increased the induction to delivery interval.

scholarly journals A study of vaginal misoprostol tablet versus intra cervical dinoprostone gel for the induction of labour

2017 ◽  
Vol 6 (4) ◽  
pp. 1404
Author(s):  
Chandni N. Badlani ◽  
Shraddha S. Shastri ◽  
Neelesh S. Risbud
Keyword(s):  
Cost Effective ◽  
Induction Of Labor ◽  
Significant Difference ◽  
Misoprostol Group ◽  
Group A ◽  
The Mean ◽  
Nicu Admission ◽  
Vaginal Misoprostol ◽  
Group B ◽  
To Receive

Background: This was a comparative study conducted to compare the effectiveness of 25 microgram of intravaginal misoprostol with intracervical dinoprostone gel in terms of efficacy of drug, feto-maternal outcome, side effects and complications of drugs.Methods: 400 nulliparas at term, admitted for induction of labor were included in this study. They were randomly selected to receive either intravaginal misoprostol or intracervical dinoprostone gel. Group A (200 women) recieved tablet misoprostol 25 micrograms vaginally 4 hrly to a maximum of 3 doses and Group B (200 women) received dinoprostone gel 0.5mg intracervically 6 hrly to a maximum of 3 doses. Comparison was done in terms of Induction to delivery interval, need for augmentation, LSCS and instrumentation rate, need for NICU admissions and cost effectiveness.Results: The mean induction to delivery interval was less in the misoprostol group than dinoprostone group (12.5 hrs vs. 20 hrs). 78% patients delivered in the first 24 hrs in misoprostol group compared to 52 % patients in dinoprostone group. Group A had a higher success rate (81% vs.76%) and also required less augmentation of labor ( 30% vs. 60%) compared to group B. Need for LSCS was also lower in misoprostol group (11% vs. 16%). Need for instrumentation and incidence of NICU admission was similar in both groups. Misoprostol was more cost effective compared to dinoprostone.Conclusions: The misoprostol group had a shorter induction to delivery interval, more number of deliveries in the first 24 hrs of induction and a reduced need of augmentation of labor with oxytocin. There was no significant difference in the rate of caesarean section, hyper-stimulation syndrome, neonatal and maternal morbidity between the two groups. Thus, misoprosol appears to be safer, cheaper and more efficacious alternative for induction of labor especially for non-fetal indications as compared to dinoprostone gel.

scholarly journals A study comparing vaginal misoprostol alone with vaginal misoprostol in combination with Foley catheter for cervical ripening and labour induction

2017 ◽  
Vol 6 (2) ◽  
pp. 485 ◽  
Author(s):  
Binti R. Bhatiyani ◽  
Manisha R. Gandhewar ◽  
Swati Kapsikar ◽  
Pradip Gaikwad
Keyword(s):  
Foley Catheter ◽  
Active Phase ◽  
Fetal Distress ◽  
Induction Of Labor ◽  
Cervical Ripening ◽  
Labour Induction ◽  
Combination Group ◽  
Maternal Complications ◽  
Misoprostol Group ◽  
Vaginal Misoprostol

Background: Induction of labor is a commonly practised intervention in modern obstetrics. The objective of this study was to compare the efficacy of vaginal misoprostol alone with vaginal misoprostol in combination with Foley catheter for labour induction. It aims to assess the induction delivery interval, the outcome of labour, the incidence of instrumental delivery and Cesarean section. The neonatal outcomes and maternal complications would also be assessed.Methods: 105 women with singleton viable pregnancies of 28 weeks or more gestation with cephalic presentation, intact membranes and an unfavorable cervix (Bishops score less than 6) were randomly assigned to induction of labor using vaginal misoprostol or Foley catheter in combination with vaginal misoprostol. Women in the misoprostol only group received 25 micrograms of misoprostol per vagina every 4 hours for a maximum of six doses. Whereas women in the combination group received vaginal misoprostol and in addition Foley catheter was introduced through the cervix for 12 hours. Interruption of the trial was done in case of failure to enter the active phase of labour after 24 hours of induction, fetal distress, hyperstimulation, hypersensitivity to drugs.Results: The induction to delivery time was shorter in misoprostol group as compared to the Foley with misoprostol group by 3 hours. There was no significant change in Bishops score after induction with Foley in combination with misoprostol as compared to misoprostol alone. There was no increase in the maternal and fetal complications in the misoprostol group as compared to Foley with misoprostol.Conclusions: Misoprostol alone was more efficacious for ripening and inducing agent as compared to Foley in combination with misoprostol.

scholarly journals Comparative study between transcervical extra-amniotic Foley’s bulb and prostaglandin E2 gel for pre-induction cervical ripening

2020 ◽  
Vol 10 (1) ◽  
pp. 119
Author(s):  
Prajakta Goswami ◽  
Kapil Annaldewar ◽  
Deepali Giri ◽  
Sachin Giri
Keyword(s):  
Prostaglandin E2 ◽  
Vaginal Delivery ◽  
Foley Catheter ◽  
Induction Of Labor ◽  
Cervical Ripening ◽  
Normal Vaginal Delivery ◽  
Bishop Score ◽  
Group A ◽  
Foley’S Catheter ◽  
Group B

Background: Induction of labor is an artificial initiation of uterine activity before the spontaneous onset of labor with the aim of achieving vaginal delivery. Various pharmacological and non-pharmacological methods have been studied for the purpose.Methods: This randomized prospective study conducted in the Department of Obstetrics and Gynaecology at the Seth V. C. Gandhi & M. A. Vora Municipal General Hospital (Rajawadi Hospital), Mumbai from June 2019 to April 2020. It included pregnant patients admitted to the labor ward for induction of labor. A total 200 women were recruited and randomly allocated to the two study groups fulfilling the following selection criteria. Of these, 100 women were included in Foley's catheter group (group A) and 100 in (group B) prostaglandin E2 (PGE2) group.  Results: The subjects included mainly were of 24-28 years age group. The period of gestation was 37-42 weeks in majority of the women in both the groups. Maximum numbers of women in both groups were primigravidae, being 66% in group A and 70% in group B. Foley catheter proved to be a highly effective pre-induction ripening agent for unfavorable cervix, compared to PGE2 gel, as evident by the mean Bishop score at 12 hours (p<0.05) and by the difference in change of Bishop score over 12 hours (p<0.05) in both groups A and B. Women in both the groups had a high rate of normal vaginal delivery, rate being significantly more in Foley’s group.Conclusions: This study concludes that extra-amniotic Foley’s catheter balloon is an effective, safe, simple, low cost, reversible, non-pharmacological mechanical method of pre-induction cervical ripening.

scholarly journals Comparative study of vaginal misoprostol and intra cervical Foley’s catheter for pre-induction cervical ripening at term

2017 ◽  
Vol 6 (4) ◽  
pp. 1283
Author(s):  
Meghna Agarwal ◽  
Varsha Kose
Keyword(s):  
Pregnant Women ◽  
Vaginal Delivery ◽  
Foley Catheter ◽  
Cervical Ripening ◽  
Catheter Group ◽  
Misoprostol Group ◽  
Group 2 ◽  
Vaginal Misoprostol ◽  
Foley’S Catheter ◽  
Group 1

Background: At times of unfavorable cervix induction of labor with cervical ripening agents were necessary. The present study was done to compare the efficacy and outcome of vaginal misoprostol and Foleys catheter in pregnant women for induction of labor.Methods: This randomized clinical trial was performed on 10o pregnant women during a time period of December 2014 to November 2016. These women were randomly divided into two groups: Misoprostol (50 patients) and Foley catheter (50 patients). For the first group, 25 mcg vaginal misoprostol was administered every 4 h up to maximum of 3 doses for a period of 12 hours. For the second group, Foley catheter 18 F, was placed through the internal os of the cervix. Data was analyzed using SPSS software 20. p <0.05 was considered statistically significant.Results: The mean age of the patients in Group 1 was 24.72±2.93 years and Group 2 was 24.12±2.88 years. Pre-induction & post-induction modified Bishop score was significantly higher in Group 1 (Misoprostol) as compared to Group 2 (Foley's catheter) in primigravida and multigravida patients. The difference in the birth weight and Apgar score at 1 min and 5 min between the two groups was statistically not significant (p>0.05). The rate of vaginal delivery was significantly more in Misoprostol group as compared to Foley’s catheter group (p<0.05). The caesarean section rate was more in Foley’s catheter group as compared to Misoprostol group and the results were statistically significant (p<0.05).Conclusions: It was concluded that misoprostol decrease the delivery time and increases the vaginal delivery compared to Foleys catheter.

scholarly journals Transvaginal ultrasonography compared with Bishop score for predicting cesarean section after induction of labor

2011 ◽  
pp. 277
Author(s):  
Fatemeh Abasalizadeh ◽  
Parvin Bastani ◽  
Kobra Hamdi ◽  
Nazli Navali ◽  
Pourmousa ◽  
...  
Keyword(s):  
Cesarean Section ◽  
Induction Of Labor ◽  
Transvaginal Ultrasonography ◽  
Bishop Score

scholarly journals Efficacy and Safety of Foley Catheter Balloon for Cervix Priming in Term Pregnancy

2017 ◽  
Vol 30 (4) ◽  
pp. 281 ◽  
Author(s):  
Catarina Policiano ◽  
Mariana Pimenta ◽  
Diana Martins ◽  
Nuno Clode
Keyword(s):  
Foley Catheter ◽  
Mode Of Delivery ◽  
Tertiary Hospital ◽  
Mechanical Effect ◽  
Induction Of Labor ◽  
Catheter Removal ◽  
Bishop Score ◽  
Delivery Time ◽  
Singleton Pregnancy ◽  
Previous Cesarean

Introduction: Foley catheter promotes cervix priming by a direct mechanical effect of distension.Material and Methods: A prospective observational study was conducted at a tertiary hospital, including all cases of induction of labor with Foley catheter between September 1, 2013 and November 30, 2015. Women were eligible if they had a singleton pregnancy with a Bishop score < 6 and a gestational age ≥ 41 weeks or a medical indication for induction of labor. The primary outcome was the Bishop score variation (difference between Bishop score before and after insertion of Foley catheter). Mode of delivery, induction-to-delivery time, uterine tachysystole with fetal decelerations, peripartum fever ≥ 38º C, maternal pain and mortality were also analyzed.Results: Within 201 inductions with Foley catheter, average increase in Bishop score after catheter placement was three (1 - 7), with only 5% (11/201) of unmodified cervix after catheter removal/extrusion. Vaginal delivery rate was 71% (142/201) and in women with a previous cesarean section (n = 40) was 37% (15/40). Average induction-to-delivery time was 38 hours (4 - 120). Uterine infection rate was 3% (6/201). There was only one case of significant vaginal bleeding which required immediate catheter removal. There has been no significative maternal or neonatal morbidity.Discussion/Conclusion: Foley catheter is a safe and effective method of cervical priming for women with an unfavorable cervix, even in the case of a previous cesarean delivery.

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