scholarly journals A comparison of the effects of desflurane and total intravenous anaesthesia on the motor evoked responses in scoliosis surgery

2017 ◽  
Vol 5 (3) ◽  
pp. 1015 ◽  
Author(s):  
Betul Isik ◽  
Güldem Turan ◽  
Suheyla Abitagaoglu ◽  
Osman Ekinci ◽  
Asu Özgültekin
Keyword(s):  
Scoliosis Surgery ◽  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia ◽  
Surgical Suture ◽  
Perioperative Bleeding ◽  
Study Results ◽  
Train Of Four ◽  
Orientation Time ◽  
End Tidal ◽  
Group D

Background: In the present study, we compared the effects of total intravenous anaesthesia (TIVA) and desflurane anaesthesia on tcMEPs in scoliosis surgery.Methods: The study included 45 patients between the ages of 18 to 50 years, and classified as ASAI-II; which were planned to undergo posterior fusion/instrumentation operations for elective scoliosis.  Anaesthesia was maintained using 50-150 mcg/kg/min propofol in Group T(TIVA), and desflurane (0.5 MAC) in Group D, and with infusions of 0.05-0.3 mcg/kg/min remifentanil at 50 % O2 + air in both groups, by applying drugs at doses so that bispectral index (BIS) would be maintained between 40 and 60 throughout the course of anaesthesia. The tcMEP responses were measured four times during the operation, and BIS, train-of-four (TOF), mean arterial pressure (MAP), heart rate(HR), and end tidal CO2(ETCO2) values were recorded simultaneously. In both group the anaesthesia was ended at the final surgical suture.  The recovery parameters were recorded.Results: The groups were found not to differ regarding the demographic characteristics, duration of the anaesthesia and the surgery, remifentanil dosage, tcMEP, the simultaneously recorded TOF, MAP, HR and ETCO2 values, and the amount of perioperative bleeding. The cooperation time and the orientation time were shorter in group D. The tcMEP responses were recorded in the appropriate times and amplitudes in both groups. Conclusions: TIVA is primarily used in routine applications in spinal surgery; however our study results revealed that 0.5 MAC desflurane may also be safely used in association with remifentanil, with the resultant correct tcMEP responses.  

scholarly journals Analgesic Effect of Butorphanol during Castration in Donkeys under Total Intravenous Anaesthesia

Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2346
Author(s):  
Paola Straticò ◽  
Augusto Carluccio ◽  
Vincenzo Varasano ◽  
Giulia Guerri ◽  
Riccardo Suriano ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Analgesic Effect ◽  
Scientific Evidence ◽  
Muscle Relaxation ◽  
Repeated Measure ◽  
Muscle Rigidity ◽  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia ◽  
Duration Of Surgery ◽  
Group D

Pain management is necessary for all surgical procedures. Little scientific evidence about drug efficacy in donkeys is available. The aim of this study was to evaluate the analgesic effect of butorphanol in donkeys undergoing orchiectomy under total intravenous anaesthesia with guaifenesin-ketamine-detomidine. A randomized blinded prospective clinical trial (Protocol n. 2021/0000338), was carried out on 18 clinically healthy donkeys undergoing bilateral orchiectomy. Patients were assigned to Group D (n = 8) or Group DB (n = 10) if receiving intravenous detomidine or detomidine-butorphanol respectively, before induction of general anaesthesia with ketamine-diazepam. Intraoperative muscle relaxation, nystagmus, palpebral reflex, heart and respiratory rate, and non-invasive blood pressure were evaluated every 2 min; time to prepare the patient, duration of surgery and anaesthesia and recovery score were recorded. Group D had significantly longer surgical time, higher heart rate, higher systolic and mean blood pressure (p < 0.05; repeated measure ANOVA), increased muscle rigidity and expression of palpebral reflex (p < 0.05; Mann–Whitney U test) than group DB. Top-ups with thiopental were statistically higher in Group D. Butorphanol and detomidine together produced a more stable anaesthetic plan. The low dosage of opioid and alpha-2-agonists and reduced rescue anaesthesia are responsible for a safer and more superficial anaesthesia, which is mandatory under field conditions.

scholarly journals A retrospective case series of computer-controlled total intravenous anaesthesia in dogs presented for neurosurgery

2004 ◽  
Vol 75 (2) ◽  
Author(s):  
K.E. Joubert ◽  
N. Keller ◽  
C.J. Du Plessis
Keyword(s):  
Case Series ◽  
Anaesthetic Management ◽  
Total Intravenous Anaesthesia ◽  
Retrospective Case ◽  
Intravenous Anaesthesia ◽  
Tumour Metastasis ◽  
Haemodynamic Stability ◽  
Syringe Driver ◽  
End Tidal ◽  
Balanced Anaesthesia

This article describes the anaesthetic management and use of total intravenous anaesthesia (TIVA) for neurosurgery in 4 dogs. Propofol in conjunction with morphine was used for the maintenance of anaesthesia. Anaesthesia was induced with either thiopentone or propofol. The program Stelpump (a target-controlled infusion program) was run on a laptop and connected to a syringe driver via an RS 232 cable. The program was found to be reliable and safe for the administration of TIVA in dogs. Invasive monitoring was required in order to monitor cardiovascular changes during surgery. Ventilation was controlled to maintain the end-tidal carbon dioxide below 40 mm Hg. The anaesthesia was characterised by haemodynamic stability. The haemodynamic stability was probably the result of the choice of TIVA and balanced anaesthesia. Intracranial pressure and oedema was controlled with dexamethasone, mannitol and ventilatory management either in combination or alone. Three dogs survived to hospital discharge and 1 dog was euthanased 2 weeks later due to tumour metastasis. The development and characterisation of the anaesthetic effects of TIVA needs to be elucidated in order to provide clinicians with rational guidelines for the appropriate use of TIVA in veterinary medicine.

scholarly journals Midazolam-Flumazenil Topical Anaesthesia for Microlaryngoscopy with Jet Ventilation

1997 ◽  
Vol 25 (4) ◽  
pp. 358-364
Author(s):  
W. Rushatamukayanunt ◽  
T. Tritrakarn
Keyword(s):  
Treated Group ◽  
Muscle Relaxants ◽  
Total Intravenous Anaesthesia ◽  
Topical Anaesthesia ◽  
Parallel Study ◽  
Jet Ventilation ◽  
Double Blind ◽  
Intravenous Anaesthesia ◽  
Single Intravenous Injection ◽  
High Incidence

A comparison between midazolam and midazolam-flumazenil for total intravenous anaesthesia in combination with topical anaesthesia and muscle relaxants was performed in a double-blind, parallel study in 40 patients scheduled for microlaryngoscopy with or without bronchoscopic procedures using jet ventilation with oxygen. A single intravenous injection of midazolam 0.3 mg/kg, lignocaine spray and muscle relaxants provided adequate anaesthesia and good operative conditions throughout the procedures, which took 20 to 30 minutes. Patients who had placebo at the end of the procedures had a longer recovery and a high incidence of airway obstruction (20%). Administration of flumazenil provided prompt awakening in 19 of 20 patients (95%) within five minutes, resulting in rapid and favourable recovery without resedation or other side-effects, while only three of 20 (15%) patients in the placebo-treated group had improved consciousness within five minutes. The simplicity and reliability of the midazolam-flumazenil technique is attractive. We consider it worthy of further investigation for wider application in clinical practice.

Disoprofol (ICI 35868) for Total Intravenous Anaesthesia

1983 ◽  
Vol 27 (2) ◽  
pp. 113-116 ◽  
Author(s):  
R. J. Fragen ◽  
E. H. J. H. Hanssen ◽  
P. A. F. Denissen ◽  
L. H. D. J. Booij ◽  
J. F. Crui.
Keyword(s):  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia
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