scholarly journals Malignant nodular hidradenoma-inguinal region clinically masquerading as squamous cell carcinoma: a case report

2019 ◽  
Vol 7 (7) ◽  
pp. 2848 ◽  
Author(s):  
Sunita S. Vernekar ◽  
Priyadharshini Bargunam
Keyword(s):  
Inguinal Lymph Node ◽  
Inguinal Region ◽  
Sweat Glands ◽  
Skin Tumour ◽  
History Of ◽  
Nodular Hidradenoma ◽  
The Right ◽  
Wedge Biopsy ◽  
Eccrine Sweat Glands ◽  
Adnexal Tumour

Malignant Nodular hidradenoma is an extremely rare aggressive tumour originating from eccrine sweat glands with an incidence of <.001%. So far less than 80 cases have been reported in the literature. It’s known for its local recurrence (50%) and metastasis (60%) and hence early diagnosis and radical treatment is mandatory. But differentiating it from its benign counterparts and other skin tumour mimics is challenging, due to its histopathological similarity & lack of diagnostic immunomarkers. Authors report a case of 65-year-old female who presented with a short 4-month history of rapidly growing ulceroproliferative growth in the right inguinal region with bilateral inguinal node enlargement, associated with pain and discharge. Wedge biopsy of left inguinal lymph node showed malignant cutaneous adnexal tumour deposits, which after excision was typed as malignant nodular hidradenoma. It was confirmed with immunohistochemistry. Patient presented with recurrence 8 months after excision.

Eccrine spiradenoma: a rare adnexal tumour with atypical presentation, a case report

2020 ◽  
pp. 1-8
Author(s):  
Adnan Salim ◽  
Muhammad Usman Tariq ◽  
Sana Zeeshan
Keyword(s):  
Case Report ◽  
Neck Region ◽  
Sweat Glands ◽  
Benign Lesions ◽  
Head And Neck Region ◽  
Strong Resemblance ◽  
Dermal Lesion ◽  
Slow Growing ◽  
Eccrine Sweat Glands ◽  
Adnexal Tumour

Abstract First described in 1934, eccrine spiradenoma (ES) is a rare, benign adnexal tumour arising from eccrine sweat glands. It commonly presents as a slow-growing nodule on the upper trunk, and head and neck region, mostly in the age bracket of 15-35 years, with no gender preference. While no established guidelines exist for optimal management of malignant ES, some therapies have been studied. The diagnosis of this entity is extremely important as it can harbour a malignant component with disastrous outcomes which may be missed due to its strong resemblance to benign lesions, such as a papilloma. Here, we present the case of a 35-year-old lady who presented with a papilloma-like growth on the upper medial aspect of the thigh which was diagnosed as eccrine spiradenoma upon excision. Keywords: Eccrine Spiradenoma, adnexal tumour, dermal lesion, case report. Continuous...

scholarly journals Infected femorocele: case report of an extremely rare surgical condition in a middle-aged lady suffering from a painful inguinal swelling

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Sabyasachi Bakshi
Keyword(s):  
Lymph Node ◽  
Femoral Hernia ◽  
Urine Analysis ◽  
Inguinal Lymph Node ◽  
Histopathological Examination ◽  
Stable Condition ◽  
Sensitivity Test ◽  
Inguinal Region ◽  
Hernia Sac ◽  
The Right

Abstract Background The hydrocele of the femoral hernia sac, an extremely rare occurrence, is termed femorocele. Very few authentically reported cases of femorocele are available in the literature. The present case, diagnosed as a case of infected femorocele, was managed successfully by excision of the femorocele sac and repair of the femoral hernia. To the best of the author’s knowledge, it is the first-ever reported case of infected femorocele. Case presentation A 30-year-old lady presented with a painful 3 cm × 2 cm swelling in the right inguinal region. Though the swelling was there for 2 years, the pain and indurations started after a trivial blunt trauma over the swelling 7 days ago. The patient was febrile and mild tachycardic but had no dysuria. The oval-shaped, tense-cystic, poorly translucent, non-pulsatile, non-reducible swelling showed no cough impulse. There was also a (1.5 cm × 0.5 cm) palpable right-sided superficial inguinal lymph node. Routine blood and urine analysis reports were normal except leukocytosis (10,000/mm3) with neutrophilia. Ultrasonography of the right inguino-labial region revealed a mildly echogenic cystic swelling without any intra-abdominal communication. Exploration of the right inguinal region revealed a cystic (3 cm × 2 cm) swelling, medial to the femoral vessels, containing amber-colored fluid. The distal sac was excised, and anatomical repair of femoral canal defect was done after transfixing the neck of the femorocele sac. Fibro-fatty-collagenous tissue with mixed inflammatory cells along with a flattened mesothelial lining cell layer was found on histopathological examination. Sections from inguinal lymph node showed reactive hyperplasia. Culture of fluid from the sac revealed growth of Escherichia coli. The patient was put on anti-inflammatory drugs and antibiotics according to a sensitivity test. Patient was discharged in stable condition after 5 days. Four months after the operation, the patient is doing well, remaining asymptomatic and without any sign of recurrence. Conclusions The hydrocele of the femoral hernia sac is an extremely rare disease. When not infected, it presents a painless inguinal soft cystic swelling, commonly in women of fourth to sixth decade. This was diagnosed intraoperatively in all cases reported till date. Excision of the sac after transfixation of the neck and anatomical repair are the treatment of choice. In elderly patients, with larger defect, the mesh repair can be opted for. The femorocele may also get infected by uropathogens, and proper antibiotics should be used after a sensitivity test.

scholarly journals Cutaneous ciliated cyst: A case report

2021 ◽  
Vol 6 (4) ◽  
pp. 295-297
Author(s):  
Yutika Amin ◽  
Kalpana Arora ◽  
Shubhangi Rairikar ◽  
Sanjay Patil
Keyword(s):  
Squamous Metaplasia ◽  
Columnar Epithelium ◽  
Sweat Glands ◽  
Young Females ◽  
Cloacal Membrane ◽  
Er Positive ◽  
The Right ◽  
Immunohistochemical Studies ◽  
Eccrine Sweat Glands ◽  
Ciliated Cyst

Cutaneous ciliated cyst are relatively rare benign lesions, found in the dermis or subcutis of the lower extremities of young females in their second and third decades. The cysts are typically lined by ciliated cuboidal to columnar epithelium, showing pseudostratified areas and focal squamous metaplasia is occasionally present. Immunohistochemical studies have demonstrated that the cysts can be PR and ER positive, similar to the epithelia of the fallopian tubes. The pathogenesis of the cyst is yet being studied, some hypotheses have been proposed including the Mullerian heterotopias, ciliated metaplasia of eccrine sweat glands, and embryonic remnants of the cloacal membrane. We report a cutaneous ciliated cyst over the right gluteus area in a 29 year old female. On histologic examination, the cyst was lined by ciliated columnar epithelium, showing occasional papillary projections.

scholarly journals Malignant Nodular Hidradenoma of the Fingertip: A Case Report

2021 ◽  
Author(s):  
Jin Soo Kim ◽  
Jung Hyun Park ◽  
Hee Jeong Lee ◽  
Byung Jun Kim ◽  
Sung Hoon Koh ◽  
...  
Keyword(s):  
Bone Erosion ◽  
Radiographic Finding ◽  
Residual Tumor ◽  
Sweat Glands ◽  
Cancer Center ◽  
Nuclear Pleomorphism ◽  
Biopsy Report ◽  
Painless Mass ◽  
Nodular Hidradenoma ◽  
Eccrine Sweat Glands

Malignant nodular hidradenoma (MNH) is an infrequent, highly malignant tumor derived from eccrine sweat glands. MNH usually occurs on the scalp, trunk, and proximal extremities, and rarely on the hand. A 55-year-old male patient visited clinics with a gradually enlarging painless mass at fingertip. It begins a year ago. Recently, it has grown rapidly and starts ulceration, and bleeding over the past 3 weeks. According to the biopsy report, it has focal necrosis, atypia, atypical mitoses, and nuclear pleomorphism suggested that the mass was MNH. After histological diagnosis, tiny bone erosion was observed in the re-read radiographic finding. For the oncologic evaluation, the patient was transferred to the cancer center. Radical amputation was performed to the residual tumor that might remain based on re-reading of radiographs. MNH of the finger is especially difficult to the diagnosis given its rarity and variable histology. When ulcerative skin lesion and radiographic bone erosion are observed, one should suspect malignancy and makes out a proper therapeutic plan after histologic biopsy.

scholarly journals Reactive Eccrine Syringofibroadenoma Associated with Neuropathy, Venous Stasis, and Diabetic Foot Ulcer

2016 ◽  
Vol 8 (2) ◽  
pp. 124-129 ◽  
Author(s):  
Thirawut Sirikham ◽  
Salinee Rojhirunsakool ◽  
Vasanop Vachiramon
Keyword(s):  
Clinical Presentation ◽  
Ectodermal Dysplasia ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Venous Stasis ◽  
Sweat Glands ◽  
Clinical Appearance ◽  
History Of ◽  
Erythematous Plaques ◽  
Eccrine Sweat Glands

Eccrine syringofibroadenoma (ESFA) is an uncommon benign adnexal neoplasm which derives from cells of the acrosyringium of eccrine sweat glands. The clinical appearance is nonspecific but the histological features are typical. Five clinical subtypes of ESFA exist: (1) solitary ESFA; (2) multiple ESFA associated with ectodermal dysplasia; (3) multiple ESFA without cutaneous features; (4) unilateral linear ESFA (nevoid), and (5) reactive ESFA associated with inflammatory or neoplastic dermatoses. We report the case of a 42-year-old man with long-standing diabetes and neuropathy, presenting with a 4-year history of asymptomatic erythematous plaques on a background of brown hyperpigmentation on the left foot. The clinical presentation and histopathological findings are compatible with reactive ESFA.

scholarly journals Syringocystadenoma Papilliferum: A Case Report and Review of the Literature

2019 ◽  
Vol 11 (1) ◽  
pp. 36-39
Author(s):  
Khalid Al Hawsawi ◽  
Amani Alharazi ◽  
Abeer Ashary ◽  
Asmaa Siddique
Keyword(s):  
Surgical Excision ◽  
Sweat Glands ◽  
Erythematous Plaque ◽  
Syringocystadenoma Papilliferum ◽  
Clinicopathological Findings ◽  
Adnexal Tumor ◽  
History Of ◽  
Epithelial Sheets ◽  
The Right ◽  
Columnar Cells

Syringocystadenoma papilliferum is a very rare, benign adnexal tumor that originates from the apocrine sweat glands. Herein, we report a 25-year-old male who presented with a 10-year history of an asymptomatic slowly growing skin lesion on his face. Skin examination revealed a solitary rounded 3 × 3 cm erythematous plaque with central crustation on the right side of his face. Punch skin biopsy was taken from the lesion. The epidermis showed downward papillomatous extensions. The dermis showed multiple epithelial sheets and dilated ducts that were lined by columnar cells. On the basis of the above clinicopathological findings, the diagnosis of syringocystadenoma papilliferum was made. The patient was reassured and referred to a surgeon for surgical excision of the lesion.

scholarly journals TORSION OF RIGHT UN-DESCENDED TESTIS;

2011 ◽  
Vol 21 (02) ◽  
pp. 418-420
Author(s):  
Muhammad Khalid
Keyword(s):  
Blood Flow ◽  
Groin Pain ◽  
Ultrasound Examination ◽  
Inguinal Region ◽  
Incision And Drainage ◽  
Doppler Examination ◽  
Inguinal Area ◽  
History Of ◽  
The Right

A case of 14 months old child with history of uncorrected right cryptorchidism isreported here who presented with right inguinal abscess after 7 days of right groin pain.. Agenitourinary examination was performed, which revealed that his right inguinal region wasswollen and fluctuant, that was 5 cm in greatest dimension. No testicle was palpable in the rightipsilateral hemiscrotum. An ultrasound examination of the inguinal area revealed aheterogeneous testicle, with no blood flow on Doppler examination. Incision and drainageconfirmed torsion of the right undescended gangrenous testis. After. Incision and drainage andorchiectomy patient showed un-eventful recovery

scholarly journals Malignant Nodular Hidradenoma: Isolated Case Report and Review of Literature

2017 ◽  
Vol 34 (2) ◽  
pp. 100-103 ◽  
Author(s):  
Sadia Armin Khan ◽  
Abu Ahmed Ashraf Ali ◽  
Shamima Ferdousi ◽  
Mahmud Riyad ◽  
Ahmed Al Hasan Mahmud
Keyword(s):  
Chest Wall ◽  
Needle Aspiration ◽  
Skin Tumor ◽  
High Rate ◽  
Sweat Glands ◽  
Infiltrative Growth Pattern ◽  
Needle Aspiration Cytology ◽  
Mitotic Figures ◽  
Nodular Hidradenoma ◽  
Eccrine Sweat Glands

Malignant Nodular Hidradenoma is an infrequent highly malignant, primary skin tumor derived from eccrine sweat glands. It has an aggressive course, with high recurrence, high rate of metastases and has very poor prognosis. It has been described as an “orphan”neoplasm. The tumor is similar to its benign counterpart but had additional features such as surface ulceration, numerous mitotic figures and infiltrative growth pattern. Pre-operative diagnosis is difficult by the fine needle aspiration cytology. Malignant nodular hidradenoma of chest wall in 35 years old women, who presented to us with a recurrent rapidly growing swelling over chest wall that grew rapidly over two months after first excision. Tissue diagnosis of first excised specimen was eccrine poroma that was similar to its benign counterpart.J Bangladesh Coll Phys Surg 2016; 34(2): 100-103

scholarly journals September 2021 Pulmonary Case of the Month: A 45­-Year-Old Woman with Multiple Lung Cysts

2021 ◽  
Vol 23 (3) ◽  
pp. 64-72
Author(s):  
Lewis Wesselius ◽  
Keyword(s):  
Ovarian Cyst ◽  
Thoracoscopic Surgery ◽  
Tube Placement ◽  
Shortness Of Breath ◽  
Lung Cysts ◽  
Operative Note ◽  
History Of ◽  
The Right ◽  
Wedge Biopsy ◽  
Video Assisted Thoracoscopic Surgery

No abstract available. Article truncated after the first 150 words. History of Present Illness A 45-year-old woman presented with increasing dyspnea on exertion and a history of recurrent pneumothoraces. In March 2018 she had laparoscopic ovarian cyst removal and noted some subsequent shortness of breath. In August 2018 she developed a right pneumothorax requiring chest tube placement. In September 2018 she had recurrent right pneumothorax and had video-assisted thoracoscopic surgery (VATS) with a right pleurodesis. The operative note from the outside VATS indicates a RUL bleb was removed and a wedge biopsy was done from posterior segment of the RUL. Pathology from the wedge biopsy reported “minimal emphysematous disease without other diagnostic abnormality”. She continued to be short of breath after the operation. PMH, SH, and FH • In 1975 she reportedly had pulmonary tuberculosis. • In 2018 the pneumothoraces, pleurodesis and the right ovarian cyst resection noted above. She is a never smoker and has no family history…

Z-line degradation and phagocytosis of sarcomeric fragments in myonecrosis

1983 ◽  
Vol 41 ◽  
pp. 790-791
Author(s):  
Melinda L. Estes ◽  
Samuel M. Chou
Keyword(s):  
Vastus Lateralis ◽  
Inflammatory Myopathy ◽  
Muscle Disease ◽  
White Female ◽  
Inflammatory Cell Infiltrate ◽  
Limb Weakness ◽  
Muscle Diseases ◽  
History Of ◽  
The Right ◽  
Mononuclear Inflammatory Cell

Many muscle diseases show common pathological features although their etiology is different. In primary muscle diseases a characteristic finding is myofiber necrosis. The mechanism of myonecrosis is unknown. Polymyositis is a primary muscle disease characterized by acute and subacute degeneration as well as regeneration of muscle fibers coupled with an inflammatory infiltrate. We present a case of polymyositis with unusual ultrastructural features indicative of the basic pathogenetic process involved in myonecrosis.The patient is a 63-year-old white female with a one history of proximal limb weakness, weight loss and fatigue. Examination revealed mild proximal weakness and diminished deep tendon reflexes. Her creatine kinase was 1800 mU/ml (normal < 140 mU/ml) and electromyography was consistent with an inflammatory myopathy which was verified by light microscopy on biopsy muscle. Ultrastructural study of necrotizing myofiber, from the right vastus lateralis, showed: (1) degradation of the Z-lines with preservation of the adjacent Abands including M-lines and H-bands, (Fig. 1), (2) fracture of the sarcomeres at the I-bands with disappearance of the Z-lines, (Fig. 2), (3) fragmented sarcomeres without I-bands, engulfed by invading phagocytes, (Fig. 3, a & b ), and (4) mononuclear inflammatory cell infiltrate in the endomysium.

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