scholarly journals Assessment of predictors and prognostic factors for locoregional recurrent breast cancer

2018 ◽  
Vol 6 (1) ◽  
pp. 287
Author(s):  
Hossam A. Elfol ◽  
Tarek M. Rageh ◽  
Mohammed A. Hamed
Keyword(s):  
Breast Cancer ◽  
Prognostic Factors ◽  
Safety Margin ◽  
Radical Mastectomy ◽  
Recurrent Breast Cancer ◽  
Oral Contraceptive Pills ◽  
Female Patients ◽  
History Of ◽  
Recurrent Breast ◽  
Locoregional Recurrent Breast Cancer

Background: Assessment of predictors and prognostic factors of locoregional recurrent breast cancer will help in management of those patients. The aim of this study was to assess and identify the predictors and prognostic factors for locoregional current breast cancer.Methods: This prospective study will be carried out on 50 female patients with history of breast cancer underwent surgical procedures either modified radical mastectomy (MRM) or conservative breast surgery (CBS) and adjuvant therapy (chemotherapy, radiotherapy, hormonal therapy).Results: Significant relationship between recurrence of breast cancer and Oral contraceptive pills of the studied female patients with history of breast cancer underwent surgery.Conclusions: Number of positive lymph nodes, lympho-vascular invasion, positive safety margin and presence of extensive intra-ductal component all these factors increase risk of recurrent breast cancer.

Preoperative MRI in Patients with Locoregional Recurrent Breast Cancer

2014 ◽  
Vol 21 (10) ◽  
pp. 1276-1285 ◽  
Author(s):  
Anton Oseledchyk ◽  
Christina Kaiser ◽  
Lisa Nemes ◽  
Michael Döbler ◽  
Alina Abramian ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Recurrent Breast Cancer ◽  
Recurrent Breast ◽  
Locoregional Recurrent Breast Cancer

scholarly journals Benign dermoscopic parallel ridge pattern in plantar hyperpigmentation due to capecitabine

2015 ◽  
pp. 79-81
Author(s):  
Linda Tognetti ◽  
Michele Fimiani ◽  
Pietro Rubegni
Keyword(s):  
Breast Cancer ◽  
Adjuvant Chemotherapy ◽  
Outpatient Clinic ◽  
Recurrent Breast Cancer ◽  
Eccrine Gland ◽  
Drug Induced ◽  
The Past ◽  
Ridge Pattern ◽  
History Of ◽  
Recurrent Breast

We report the case of a 37-year-old woman (phototype II) who presented at our outpatient clinic with a two-month history of hyperpigmented plantar macules. Medical history revealed that the patient had taken capecitabine in the past three months as adjuvant chemotherapy for recurrent breast cancer. Dermoscopic examination of the plantar macules showed parallel ridge pattern with pigmentation in the furrows without obliteration of eccrine gland apertures. Besides in acral melanoma, parallel ridge pattern can also be observed in benign plantar lesions, such as congenital or acquired acral nevi, subcorneal hemorrhage, dye-related pigmentation and drug-induced hyperpigmentation, especially in patients with phototypes III-VI. The few reported cases of capecitabine-induced hyperpigmentation have been associated with hand and foot syndrome in patients with phototypes IV-V and palmar as well as plantar involvement.

scholarly journals Impact of Technique and Schedule of Reirradiation Plus Hyperthermia on Outcome after Surgery for Patients with Recurrent Breast Cancer

Cancers ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 782 ◽  
Author(s):  
Sabine Oldenborg ◽  
Rob van Os ◽  
Bing Oei ◽  
Philip Poortmans
Keyword(s):  
Breast Cancer ◽  
Local Control ◽  
Survival Rates ◽  
Recurrent Breast Cancer ◽  
Complete Excision ◽  
Patients At Risk ◽  
The Difference ◽  
Grade 3 ◽  
Recurrent Breast ◽  
Locoregional Recurrent Breast Cancer

Purpose: Combining reirradiation (reRT) with hyperthermia (HT) has shown to be of high therapeutic value for patients with loco-regionally recurrent breast cancer. The purpose of this study was to compare the long-term therapeutic effect and toxicity of reRT + HT following surgery of loco-regionally recurrent breast cancer using two different reRT regimens. Methods: The reRT regimen of the 78 patients treated in Institute A consisted of 8 × 4 Gy twice a week using mostly abutted photon-electron fields. The 78 patients treated in Institute B received a reRT regimen of 12 × 3 Gy, four times a week with single or multiple electron fields. Superficial hyperthermia was applied once a week in Institute A and twice a week in Institute B. Both institutes started HT treatment within 1 hour after reRT and used the same 434-MHz systems to heat the tumor area to 41–43 °C. Results: The 5-year-infield local control (LC) rates were similar; however, the 5-year-survival rates were 13% lower in Institute A. Most remarkable was the difference in risk with respect to 5-year ≥ grade 3 toxicity, which was more than twice as high in Institute A. Conclusion: The combination of reirradiation and hyperthermia after macroscopically complete excision of loco-regional breast cancer recurrences provides durable local control in patients at risk for locoregional recurrent breast cancer. Treatment is well tolerated with the 12 × 3 Gy schedule with limited-sized electron fields.

Delineation of an unknown significance FANCA genetic variant in a recurrent breast cancer patient

2021 ◽  
Vol 14 (3) ◽  
pp. e241251
Author(s):  
Stavroula Kastora ◽  
Olga Triantafyllidou ◽  
Georgios Kounidas ◽  
Nikolaos Vlahos
Keyword(s):  
Breast Cancer ◽  
Bilateral Breast Cancer ◽  
Recurrent Breast Cancer ◽  
Complementation Group ◽  
Fanconi Anaemia ◽  
Unknown Significance ◽  
History Of ◽  
Common Clinical Practice ◽  
Recurrent Breast

Fanconi anaemia is a heterogeneous condition associated with mutations in the Fanconi anaemia complementation group (FANC). The FANC group has also been extensively associated with tumourigenesis due to its intricate association with the cellular repair mechanism. In this case report, we are drawing initial associations between a previously unreported FANC-A gene point mutation (P1222L) and familial breast cancer, by examining the presentation and management of a 65-year-old female patient with history of bilateral breast cancer of two different histological categories (ductal and in situ lobular). Here, we present a further genetic analysis beyond the common clinical practice to understand the patient’s genetic predisposition and improve their long-term management.

Management of isolated locoregional recurrent breast cancer after mastectomy

1989 ◽  
Vol 17 ◽  
pp. 180-181
Author(s):  
Karen Halverson ◽  
Carlos A. Perez ◽  
Robert R. Kuske ◽  
Delia Garcia ◽  
Barbara Fineberg
Keyword(s):  
Breast Cancer ◽  
Recurrent Breast Cancer ◽  
Recurrent Breast ◽  
Locoregional Recurrent Breast Cancer

Prognostic Factors for Advanced/Recurrent Breast Cancer Treated With Immune-cell Therapy

2021 ◽  
Vol 41 (8) ◽  
pp. 4133-4141
Author(s):  
RISHU TAKIMOTO ◽  
TAKASHI KAMIGAKI ◽  
SACHIKO OKADA ◽  
HIROSHI IBE ◽  
ERI OGUMA ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factors ◽  
Cell Therapy ◽  
Immune Cell ◽  
Recurrent Breast Cancer ◽  
Recurrent Breast
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