scholarly journals Evaluation of fine needle aspiration cytology among lymphadenopathy patients in Ambedkarnagar, Uttar Pradesh, India

2017 ◽  
Vol 4 (2) ◽  
pp. 519
Author(s):  
Arshad Ikram ◽  
Syed Esam Mahmood

Background: Surgical fine needle aspiration cytology is most popular diagnostic aid in patients with lymphadenopathy.Methods: This one year observational study comprised of aspirate collected from lymph nodes of patients attending Mahamaya Rajkiya Allopathic Medical College and Hospital, Ambedkarnagar, Uttar Pradesh, India. Fine needle aspiration was performed in all the patients and slides were stained with H and E, PAP and Ziehl Neelsen stains. SPSS was used for data analysis. Fischer’s Exact test was applied.Results: Out of the 51 patients, the most common site of lymph node aspirated was cervical (72.5%). A higher proportion of cases were diagnosed as chronic nonspecific lymphadenitis (23.5%) followed by granulomatous abscess (23.5%), tubercular lymph node (21.6%) and reactive (17.6%).  A significant association found between FNAC diagnosis and age was found (p≤ 0.05).Conclusions: FNAC is a simple and useful procedure in patients with lymphadenopathy.

Author(s):  
Manish Munjal ◽  
Nitika Tuli ◽  
Porshia Rishi ◽  
Harjinder Singh ◽  
Shivam Talwar ◽  
...  

Background: Diseases of thyroid are of great importance since most of them are amenable to surgical or medical management. Objective of this study was to study the incidence, gender profile, intervention undertaken, fine needle aspiration cytology and histopathological profile of thyroid lesions and correlation of FNAC and HPE studies done after surgical intervention.Methods: This is a prospective study of the patients with thyroid swelling presenting to the head and neck clinic of otorhinolaryngology and head and neck surgery, Dayanand Medical College, Ludhiana over a time period of 2 years (January 2018 to November 2019). All the cases were subjected to a thorough clinical examination followed by evidence-based interventions. Fine needle aspiration cytology was done in all the cases preoperatively as out-patients basis and histopathologically confirmed postoperatively.Results: There were 80/212 subjects presenting in outpatient head and neck clinics of otorhinolaryngology and head and neck services of Dayanand Medical College and Hospital over a period of two years (January 2018 to December 2019). 57 were benign pathologies and 23 malignant. Multinodular goiter was commonest amongst benign (45 cases/78.9%) and papillary carcinoma (19 cases/82.6%) amongst malignant pathologies. Hemithyroidectomy was done in 41 patients (51.2%) while total thyroidectomy was done in 20 patients (25%) while total thyroidectomy with lymph node clearance was done in 19 patients (23.7%). Lymph node involvement was seen in 21.7% (5 cases out of 23 malignant) patients. Fine needle aspiration cytology finding and histopathological examination diagnosis could be corelated in 75 patients (93.75%).Conclusions: Benign lesions are more common than the malignant and amongst malignant papillary carcinoma is the commonest necessitating lymph node clearance.


2014 ◽  
Vol 19 (2) ◽  
pp. 110-118
Author(s):  
Mohammad Amzad Hossain ◽  
Md Zahedul Alam ◽  
Md Rojibul Haque ◽  
Md Nazmul Haque ◽  
KM Nurul Alam ◽  
...  

Objective: To evaluate the role of Fine Needle Aspiration Cytology in the preoperative diagnosis of malignancy in parotid and submandibular gland neoplasm. Methods: This cross sectional study on 50 cases was conducted in the Department of Otolaryngology and Head-Neck Surgery of Sir Salimullah Medical College Mitford Hospital and Dhaka Medical College Hospital from January’2009 to June 2010. Results: Fine needle aspiration cytology findings of our all 50 cases were compared with postoperative histopathological reports. Out of the 50 cases, in 36(72%) cases of benign neoplasm and 7(14%) cases of malignant neoplasm, pre-operative FNAC findings and post operative histopathological findings were same. In 7 cases, FNAC and post operative histopathological findings did not matched. These were 2 (4%) false positive and 5 (10%) false negative result.In our study sensitivity of FNAC for reporting malignancy was 58.33%, specificity to rule out malignancy was 94.73% and overall accuracy in detecting malignant tumour was 86%. Positive predictive value and negative value were 77.77% and 87.80% respectively. It can be concluded that fine needle aspiration cytology is a safe, cheap and useful preoperative diagnostic tool in the diagnosis of malignancy in parotid and submandibular gland, but as fine needle aspiration cytology partly depends on operator skill, it may give false negative and false positive result. Conclusion: FNAC is a useful preoperative diagnostic tool for malignant parotid and submandibular glands with high specificity and sensitivity. DOI: http://dx.doi.org/10.3329/bjo.v19i2.17634 Bangladesh J Otorhinolaryngol 2013; 19(2): 110-118


2020 ◽  
Vol 22 (4) ◽  
pp. 260-265
Author(s):  
Neeta Kafle ◽  
B Koirala ◽  
SU Kafle ◽  
M Singh ◽  
A Sinha

More than 50% of the world’s population has at least a thyroid nodule. Detail clinical examination and radiology may help in diagnosing thyroid lesions but the management depends upon the cytopathological diagnosis. Optimum use of fine needle aspiration cytology (FNAC) and better understanding of cytomorphological characteristic of thyroid lesions by using Bethesda system, triaging of patients who are to be treated medically or surgically is more accurate. The objective of this present study is cytopathological evaluation of thyroid lesions based on Bethesda System in patients attending Birat Medical College and Teaching Hospital. The objective was also to correlate the cytological findings with histopathological findings where ever possible. A total of 104 patients with thyroid lesions underwent fine needle aspiration cytology in a period of a year (September 1, 2019 to August 31, 2020). Cytological features were evaluated and classified according to the Bethesda system. Histopathological features were evaluated and correlated wherever available. Among 104 patients with thyroid lesions 93 were female and 11 were male. Four cases turned out to be non diagnostic, 85 benign, three Atypia of undetermined significance, three Suspicious for follicular neoplasm and eight Suspicious of malignancy and one Malignant according to Bethesda system. Histopathology specimen was received in 31 patients out of whom 20 (64.5%) patients were reported as colloid nodule, two follicular adenoma, one Hurthle cell adenoma, six papillary carcinoma and two follicular carcinoma. Medullary carcinoma and anaplastic carcinoma were not seen in the patients evaluated. Specificity and sensitivity of fine needle aspiration cytology was 94.7% and 88.9% respectively. Thus reporting thyroid lesions FNAC with Bethesda system allow a more specific cytological diagnosis.


1970 ◽  
Vol 7 (1) ◽  
pp. 1-5 ◽  
Author(s):  
G Shakya ◽  
S Malla ◽  
KN Shakya ◽  
R Shrestha

Background: Fine Needle Aspiration Cytology (FNAC) is a reliable and least expensive method suitable for developing countries like Nepal for the investigation of lymphadenopathy. Knowledge about the pattern of lymphadenopathy is useful in pathological reporting as well as in many clinical settings with diagnostic dilemma. This is a baseline study to investigate the pattern of cervical lymphadenopathy by lymph node FNAC in Nepalese population. Methods: A retrospective study was conducted by critically analyzing the case reports on cervical lymph node FNAC from three years' records (July 2005 to June 2008) at the National Public Health Laboratory, Teku, Kathmandu. Review of all cytological reports were done according to standard guidelines and the diagnosis was classified and correlated with patients' age and ethnicity to explore the pattern and association. Results: Of 508 cervical lymph node FNAC cases, 50.4% was reactive non-specific, 22.4% was tubercular, 4.8 % malignant, 10% chronic granulomatous and the remaining was acute suppurative (12.4%). Highest incidence of malignancy was seen in the fifth decade (50%). Whereas, tubercular lymphadenopathy was found with increasing frequency through childhood (10.5%) and adolescence (21.7%) to young adulthood (30.4%), probably indicative of waning immunity of BCG vaccination. Ethnic groups comprising of Tamang, Sherpa and Bhote had the highest incidence of malignant as well as tubercular lymphadenopathy. Conclusion: The relationship of malignant and tubercular lymphadenopthy with age and ethnicity deserves further study. Efforts at preventing tubercular and early diagnosing malignant lymphadenopathy and reducing morbidity in general will find great usefulness in such associations. Key words: Cervical Lymphadenopathy, Fine Needle Aspiration Cytology, Pattern   DOI: 10.3126/jnhrc.v7i1.2267 Journal of Nepal Health Research Council Vol. 7, No. 1, 2009 April 1-5


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