scholarly journals Profile of thyroid lesions presenting at a tertiary care health centre of North India: 2-year pilot study (2018-2019)

Author(s):  
Manish Munjal ◽  
Nitika Tuli ◽  
Porshia Rishi ◽  
Harjinder Singh ◽  
Shivam Talwar ◽  
...  

Background: Diseases of thyroid are of great importance since most of them are amenable to surgical or medical management. Objective of this study was to study the incidence, gender profile, intervention undertaken, fine needle aspiration cytology and histopathological profile of thyroid lesions and correlation of FNAC and HPE studies done after surgical intervention.Methods: This is a prospective study of the patients with thyroid swelling presenting to the head and neck clinic of otorhinolaryngology and head and neck surgery, Dayanand Medical College, Ludhiana over a time period of 2 years (January 2018 to November 2019). All the cases were subjected to a thorough clinical examination followed by evidence-based interventions. Fine needle aspiration cytology was done in all the cases preoperatively as out-patients basis and histopathologically confirmed postoperatively.Results: There were 80/212 subjects presenting in outpatient head and neck clinics of otorhinolaryngology and head and neck services of Dayanand Medical College and Hospital over a period of two years (January 2018 to December 2019). 57 were benign pathologies and 23 malignant. Multinodular goiter was commonest amongst benign (45 cases/78.9%) and papillary carcinoma (19 cases/82.6%) amongst malignant pathologies. Hemithyroidectomy was done in 41 patients (51.2%) while total thyroidectomy was done in 20 patients (25%) while total thyroidectomy with lymph node clearance was done in 19 patients (23.7%). Lymph node involvement was seen in 21.7% (5 cases out of 23 malignant) patients. Fine needle aspiration cytology finding and histopathological examination diagnosis could be corelated in 75 patients (93.75%).Conclusions: Benign lesions are more common than the malignant and amongst malignant papillary carcinoma is the commonest necessitating lymph node clearance.

2020 ◽  
Vol 22 (4) ◽  
pp. 260-265
Author(s):  
Neeta Kafle ◽  
B Koirala ◽  
SU Kafle ◽  
M Singh ◽  
A Sinha

More than 50% of the world’s population has at least a thyroid nodule. Detail clinical examination and radiology may help in diagnosing thyroid lesions but the management depends upon the cytopathological diagnosis. Optimum use of fine needle aspiration cytology (FNAC) and better understanding of cytomorphological characteristic of thyroid lesions by using Bethesda system, triaging of patients who are to be treated medically or surgically is more accurate. The objective of this present study is cytopathological evaluation of thyroid lesions based on Bethesda System in patients attending Birat Medical College and Teaching Hospital. The objective was also to correlate the cytological findings with histopathological findings where ever possible. A total of 104 patients with thyroid lesions underwent fine needle aspiration cytology in a period of a year (September 1, 2019 to August 31, 2020). Cytological features were evaluated and classified according to the Bethesda system. Histopathological features were evaluated and correlated wherever available. Among 104 patients with thyroid lesions 93 were female and 11 were male. Four cases turned out to be non diagnostic, 85 benign, three Atypia of undetermined significance, three Suspicious for follicular neoplasm and eight Suspicious of malignancy and one Malignant according to Bethesda system. Histopathology specimen was received in 31 patients out of whom 20 (64.5%) patients were reported as colloid nodule, two follicular adenoma, one Hurthle cell adenoma, six papillary carcinoma and two follicular carcinoma. Medullary carcinoma and anaplastic carcinoma were not seen in the patients evaluated. Specificity and sensitivity of fine needle aspiration cytology was 94.7% and 88.9% respectively. Thus reporting thyroid lesions FNAC with Bethesda system allow a more specific cytological diagnosis.


2015 ◽  
Vol 04 (02) ◽  
pp. 80-85
Author(s):  
Junu Devi ◽  
Kunja Lal Talukdar

Abstract Background : Fine needle aspiration cytology is a simple, quick,inexpensive and minimally invasive technique used to diagnose head and neck neoplasms commonly originated from cervical lymph node, thyroid, parotid and other salivary glands. In this study a correlation was done between cytology and histopathology whenever surgical specimens were available. Aim : To assess the frequency of various benign and malignant neoplasms in different age groups and to evaluate the sensitivity, specificity of fine needle aspiration cytology(FNAC) in head and neck neoplasms. Materials and method : The study was conducted between September 2011 to August 2013 and total 249 cases of head and neck neoplasms were analysed. Patients between 1 to 80 years were included in the study. Fine needle aspiration cytology (FNAC) diagnosis was correlated with histopathology whenever possible. Results: Out of 249 head and neck neoplasms 55.42% were from lymph node, 19.28% were from salivary gland, 14.86% were from thyroid gland, 1.20% were nasal mass, 9.24% from other sites (skin and soft tissue). M:F was 1.4:1. Most commonly affected age group was 51-60 years. Metastatic squamous cell carcinoma was most commonly encountered neoplastic lesion. Overall sensitivity, specificity oflme needle aspiration cytology(FNAC) were 97.92% and 91.67% respectively. Conclusion : Fine needle aspiration cytology is a highly sensitive, specific and has a definite role in diagnosing most of the head and neck neoplasms.


2018 ◽  
Vol 1 (2) ◽  
pp. 83-86
Author(s):  
Laxman Banstola ◽  
Swasti Sharma ◽  
Bijaya Gautam

Background: Head and neck swelling is a frequently encountered complaint in the outpatient department. A wide plethora of conditions give rise to head and neck lumps. Sometimes the diagnosis of these lesions is apparent from the site and associated features, while at other times the cause for mass in this region can be confusing. Fine needle aspiration cytology has emerged as a reliable tool for clinching the diagnosis in head and neck swellings. Methods and Materials: A retrospective study was conducted in the department of Pathology, Pokhara Academy of Health Sciences, Western Regional Hospital, Pokhara. Details of diagnosed cases of HN swellings from the period of November 2015 to February 2018 were obtained from recorded data. Descriptive statistics was applied from the data collected for analysis. Results: Out of total 456 patients included from a period of 28 months, female patients outnumbered male patients by 1.5 times. The most common age group of presentation for head and neck swellings was observed to be 20-29 years, with 93 patients which comprised of 20.39% of total. Highest incidence was that of lymph node swellings (55.04%) followed by thyroid swellings (21.49%). Conclusion: Lymph node pathology was determined to be the commonest cause for head and neck mass. FNAC is a reliable and inexpensive means in investigating such lesions, which provides immense help in treatment of patients.


2017 ◽  
Vol 4 (2) ◽  
pp. 519
Author(s):  
Arshad Ikram ◽  
Syed Esam Mahmood

Background: Surgical fine needle aspiration cytology is most popular diagnostic aid in patients with lymphadenopathy.Methods: This one year observational study comprised of aspirate collected from lymph nodes of patients attending Mahamaya Rajkiya Allopathic Medical College and Hospital, Ambedkarnagar, Uttar Pradesh, India. Fine needle aspiration was performed in all the patients and slides were stained with H and E, PAP and Ziehl Neelsen stains. SPSS was used for data analysis. Fischer’s Exact test was applied.Results: Out of the 51 patients, the most common site of lymph node aspirated was cervical (72.5%). A higher proportion of cases were diagnosed as chronic nonspecific lymphadenitis (23.5%) followed by granulomatous abscess (23.5%), tubercular lymph node (21.6%) and reactive (17.6%).  A significant association found between FNAC diagnosis and age was found (p≤ 0.05).Conclusions: FNAC is a simple and useful procedure in patients with lymphadenopathy.


2014 ◽  
Vol 19 (2) ◽  
pp. 110-118
Author(s):  
Mohammad Amzad Hossain ◽  
Md Zahedul Alam ◽  
Md Rojibul Haque ◽  
Md Nazmul Haque ◽  
KM Nurul Alam ◽  
...  

Objective: To evaluate the role of Fine Needle Aspiration Cytology in the preoperative diagnosis of malignancy in parotid and submandibular gland neoplasm. Methods: This cross sectional study on 50 cases was conducted in the Department of Otolaryngology and Head-Neck Surgery of Sir Salimullah Medical College Mitford Hospital and Dhaka Medical College Hospital from January’2009 to June 2010. Results: Fine needle aspiration cytology findings of our all 50 cases were compared with postoperative histopathological reports. Out of the 50 cases, in 36(72%) cases of benign neoplasm and 7(14%) cases of malignant neoplasm, pre-operative FNAC findings and post operative histopathological findings were same. In 7 cases, FNAC and post operative histopathological findings did not matched. These were 2 (4%) false positive and 5 (10%) false negative result.In our study sensitivity of FNAC for reporting malignancy was 58.33%, specificity to rule out malignancy was 94.73% and overall accuracy in detecting malignant tumour was 86%. Positive predictive value and negative value were 77.77% and 87.80% respectively. It can be concluded that fine needle aspiration cytology is a safe, cheap and useful preoperative diagnostic tool in the diagnosis of malignancy in parotid and submandibular gland, but as fine needle aspiration cytology partly depends on operator skill, it may give false negative and false positive result. Conclusion: FNAC is a useful preoperative diagnostic tool for malignant parotid and submandibular glands with high specificity and sensitivity. DOI: http://dx.doi.org/10.3329/bjo.v19i2.17634 Bangladesh J Otorhinolaryngol 2013; 19(2): 110-118


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