scholarly journals Correlation between echocardiographic left ventricular hypertrophy and microalbuminuria among hypertensive subjects in Olabisi Onabanjo university teaching hospital, Sagamu, Nigeria

2020 ◽  
Vol 7 (7) ◽  
pp. 1141
Author(s):  
Olajide O. Oresegun ◽  
Oluranti B. Familoni ◽  
Taiwo O. Olunuga ◽  
Akintunde Akinpelu

Background: Left ventricular hypertrophy is an adaptive response to volume and/or pressure overload, especially in hypertensive subjects. Microalbuminuria is a well-known predictor of poor cardiovascular outcomes in patients with hypertension. The purpose of this study was to determine the prevalence of microalbuminuria in hypertensive subjects and its relationship with LVH defined by echocardiogram in adult hypertensive subjects.Methods: The study was a cross-sectional comparative one involving 88 hypertensive volunteers with age and sex-matched normotensive controls. Detailed history, physical examination, urine assessment for microalbuminuria and echocardiogram were carried out on all participants.Results: The overall prevalence rate of microalbuminuria in the study was 29.5%. The prevalence of microalbuminuria in hypertensive subjects (43.2%) was significantly higher than in the normotensive counterparts (15.9%) (p=0.001). The prevalence of microalbuminuria in hypertensive subjects with echocardiographic LVH (81.0%) was significantly higher than in hypertensive participants without echocardiographic LVH (31.3%) (p=0.001). There was a positive correlation between left ventricular mass defined by echocardiogram and urinary albumin excretion in hypertensive subjects (r =0.422, p= 0.001).Conclusions: There is a high prevalence of microalbuminuria among hypertensive adults, especially those with left ventricular hypertrophy. There is also a positive correlation between echocardiographic left ventricular mass and urinary albumin excretion among adult hypertensive subjects.

2006 ◽  
Vol 1 (6) ◽  
pp. 1187-1190 ◽  
Author(s):  
Niloofar Nobakhthaghighi ◽  
Mohammed Kamgar ◽  
Mir R. Bekheirnia ◽  
Kim McFann ◽  
Raymond Estacio ◽  
...  

2006 ◽  
Vol 21 (10) ◽  
pp. 2780-2787 ◽  
Author(s):  
Wolfgang Lieb ◽  
Bjoern Mayer ◽  
Jan Stritzke ◽  
Angela Doering ◽  
Hans-Werner Hense ◽  
...  

2010 ◽  
Vol 77 (12) ◽  
pp. 1115-1122 ◽  
Author(s):  
Thorsten Reffelmann ◽  
Marcus Dörr ◽  
Henry Völzke ◽  
Nele Friedrich ◽  
Alexander Krebs ◽  
...  

VASA ◽  
2013 ◽  
Vol 42 (4) ◽  
pp. 284-291 ◽  
Author(s):  
Seong-Woo Choi ◽  
Hye-Yeon Kim ◽  
Hye-Ran Ahn ◽  
Young-Hoon Lee ◽  
Sun-Seog Kweon ◽  
...  

Background: To investigate the association between ankle-brachial index (ABI), left ventricular hypertrophy (LVH) and left ventricular mass index (LVMI) in a general population. Patients and methods: The study population consisted of 8,246 people aged 50 years and older who participated in the baseline survey of the Dong-gu Study conducted in Korea between 2007 and 2010. Trained research technicians measured LV mass using mode M ultrasound echocardiography and ABI using an oscillometric method. Results: After adjustment for risk factors and common carotid artery intima-media thickness (CCA-IMT) and the number of plaques, higher ABIs (1.10 1.19, 1.20 - 1.29, and ≥ 1.30) were significantly and linearly associated with high LVMI (1.10 - 1.19 ABI: β, 3.33; 95 % CI, 1.72 - 4.93; 1.20 - 1.29 ABI: β, 6.51; 95 % CI, 4.02 - 9.00; ≥ 1.30 ABI: β, 14.83; 95 % CI, 6.18 - 23.48). An ABI of 1.10 - 1.19 and 1.20 - 1.29 ABI was significantly associated with LVH (1.10 - 1.19 ABI: OR, 1.35; 95 % CI, 1.19 - 1.53; 1.20 - 1.29 ABI: OR, 1.59; 95 % CI, 1.31 - 1.92) and ABI ≥ 1.30 was marginally associated with LVH (OR, 1.73; 95 % CI, 0.93 - 3.22, p = 0.078). Conclusions: After adjustment for other cardiovascular variables and CCA-IMT and the number of plaques, higher ABIs are associated with LVH and LVMI in Koreans aged 50 years and older.


2020 ◽  
Vol 73 (5) ◽  
pp. 943-946
Author(s):  
Olha M. Chernatska ◽  
Liudmyla N. Prystupa ◽  
Hanna A. Fadieieva ◽  
Alina V. Liashenko ◽  
Yuliia O. Smiianova

The aim is the analysis of hyperuricemia influence on the heart features in patients with arterial hypertension. Materials and methods: We include 75 patients with arterial hypertension which were divided in two groups according to the level of uric acid in the blood, 30 practically healthy people. Patients from the I group (n = 40) had arterial hypertension and coexistent hyperuricemia; ІІ (n = 35) – arterial hypertension. Left ventricular mass index was determined for left ventricular hypertrophy confirmation. We used clinical, anthropometric, biochemical, instrumental, statistical method. Serum uric acid level was observed by the reaction with uricase. Left ventricular mass index was calculated as left ventricular mass to body surface area ratio. The results were analyzed statistically by SPSS 21 and Graphpad. Results: Left ventricular mass index was significantly higher (р = 0,0498) in patients from the І group (109,7 ± 3,21) g/m2 comparable with the ІІ (97,6 ± 5,35) g/m2 and increased in proportion to the biggest level of uric acid (r = 0,31; p = 0,04) in patients with arterial hypertension and hyperuricemia. Conclusions: Concentric and excentric left ventricular hypertrophy, increased left ventricular mass index proportionally to uric acid levels (r = 0,31; p = 0,04) is the confirmation of important role of hyperuricemia in the left ventricular hypertrophy development in patients with arterial hypertension.


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