scholarly journals An outbreak of diarrhoeal disease of El Tor Vibrio cholerae O1 Ogawa in and around Yavatmal district, Maharashtra, India in 2018

2020 ◽  
Vol 7 (4) ◽  
pp. 1297
Author(s):  
Swati S. Kale ◽  
Pragati A. Bulle ◽  
Durgesh G. Deshmukh ◽  
Supriya S. Tankhiwale ◽  
Vivek M. Gujar
Keyword(s):  
Vibrio Cholerae ◽  
Diarrhoeal Disease ◽  
Cholera Outbreak ◽  
Vibrio Cholerae O1 ◽  
Stool Samples ◽  
El Tor

Background: Epidemics of cholera have been reported from various parts of India. We investigated the epidemic of cholera that occurred in and around Yavatmal district in Maharashtra, India 2018, reported during March to July.Methods: 711 stool samples collected from diarrhea patients were bacteriologically analyzed for their identification and antibiogram of Vibrio cholera.Results: The cholera outbreak was caused by V. cholerae O1 Ogawa biotype El Tor. All the V. cholerae isolates from the stool samples were sensitive to tetracycline, doxycycline, ofloxacin, ciprofloxacin gentamycin, cotrimoxazole and resistant to ampicillin and ceftazidime.Conclusions: The present outbreak was due to V. cholerae O1 Ogawa El Tor which seems to have completely replaced O139 serogroup of the previous outbreaks during the last decade.

Antibiotic Susceptibility Profile of ‘Vibrio Cholerae O1 Biotype El Tor Serotype Ogawa’ Outbreak in North Delhi, India

2018 ◽  
Vol 13 (04) ◽  
pp. 277-282
Author(s):  
Pragnya Jena ◽  
Abha Sharma ◽  
Shalini Duggal ◽  
Tanisha Bharara ◽  
Renu Gur
Keyword(s):  
Vibrio Cholerae ◽  
World Health ◽  
Resistance Pattern ◽  
Public Health Issue ◽  
Cholera Outbreak ◽  
Improved Sanitation ◽  
Vibrio Cholerae O1 ◽  
Stool Samples ◽  
Health Organization ◽  
El Tor

Background Cholera remains a public health issue, especially in developing countries. We report a cholera outbreak in North Delhi. Objective To report the causative agent of outbreak and to characterize, biotype, and analyze antimicrobial resistance pattern of V. cholerae isolated from cholera patients admitted to our hospital. The outbreak occurred from July 2016 to August 2016. Materials and Methods A total of 179 stool samples from pediatrics department were received and processed according to the current Clinical and Laboratory Standards Institute (CLSI) guidelines. Results Out of 179 stool samples received by the laboratory, 26 samples grew Vibrio cholerae O1 Biotype El Tor. Cefotaxime and ceftriaxone were the most sensitive drugs. All isolates were resistant to cotrimoxazole followed by tetracycline. Conclusion According to the World Health Organization (WHO), cholera is becoming endemic in Delhi. Emergence of multiple antibiotic-resistant cholera isolates is a concern. Prompt identification and notification of cholera are the key measures to avert cholera outbreak. Clean water supply and improved sanitation measures should be taken for prevention of cholera.

Prevalence of Vibrio cholerae O1 El Tor variant in a cholera-endemic zone of Kenya

2014 ◽  
Vol 63 (3) ◽  
pp. 415-420 ◽  
Author(s):  
Suleiman M. Saidi ◽  
Nityananda Chowdhury ◽  
Sharda P. Awasthi ◽  
Masahiro Asakura ◽  
Atsushi Hinenoya ◽  
...  
Keyword(s):  
Vibrio Cholerae ◽  
Cholera Outbreak ◽  
Lake Region ◽  
High Fatality Rate ◽  
Clonal Origin ◽  
Variant Clone ◽  
Vibrio Cholerae O1 ◽  
Stool Samples ◽  
El Tor ◽  
Cholix Toxin

Since 2007, Kenya has experienced an increase in cholera outbreaks characterized by a high fatality rate. In this study, we characterized 81 Vibrio cholerae isolates from diarrhoeal stool samples in Nyanza, a cholera-endemic lake region of Kenya, for virulence properties, clonality and antibiotic susceptibility. Eighty of these isolates were V. cholerae O1 El Tor variants carrying the classical ctxB gene sequence, while one isolate was V. cholerae non-O1/O139. All of the El Tor variants were of clonal origin, as revealed by PFGE, and were susceptible to ampicillin, tetracycline, ciprofloxacin, fosfomycin, kanamycin and norfloxacin. However, the isolates showed resistance to sulfamethoxazole/trimethoprim and streptomycin, and intermediate resistance to nalidixic acid, chloramphenicol and imipenem. The non-O1/O139 isolate carried the cholix toxin II gene (chxA II) and was susceptible to all antimicrobials tested except ampicillin. We propose that an El Tor variant clone caused the Nyanza cholera outbreak of 2007–2008.

Cholera outbreak investigation, Bhadola, Delhi, India, April–May 2018

2020 ◽  
Vol 114 (10) ◽  
pp. 762-769
Author(s):  
Akhileshwar Singh ◽  
Rakesh Gupta ◽  
Tanzin Dikid ◽  
Ekta Saroha ◽  
Naresh Chand Sharma ◽  
...  
Keyword(s):  
Vibrio Cholerae ◽  
Fecal Coliforms ◽  
Prevention Measures ◽  
Cholera Outbreak ◽  
Public Health Action ◽  
The North ◽  
Municipal Water ◽  
Health Action ◽  
Vibrio Cholerae O1 ◽  
Stool Samples

Abstract Background In the Gangetic plains of India, including Delhi, cholera is endemic. On 10 May 2018, staff at the north Delhi district surveillance unit identified a laboratory-confirmed cholera outbreak when five people tested positive for Vibrio cholerae O1 Ogawa serotype in Bhadola. We investigated to identify risk factors and recommend prevention measures. Methods We defined a case as ≥3 loose stools within 24 h in a Bhadola resident during 1 April–29 May 2018. We searched for cases house-to-house. In a 1 : 1 unmatched case control study, a control was defined as an absence of loose stools in a Bhadola resident during 1 April–29 May 2018. We selected cases and controls randomly. We tested stool samples for Vibrio cholerae by culture. We tested drinking water for fecal contamination. Using multivariable logistic regression we calculated adjusted ORs (aORs) with 95% CIs. Results We identified 129 cases; the median age was 14.5 y, 52% were females, 27% were hospitalized and there were no deaths. Symptoms were abdominal pain (54%), vomiting (44%) and fever (29%). Among 90 cases and controls, the odds of illness were higher for drinking untreated municipal water (aOR=2.3; 95% CI 1.0 to 6.2) and not knowing about diarrhea transmission (aOR=4.9; 95% CI 1.0 to 21.1). Of 12 stool samples, 6 (50%) tested positive for Vibrio cholerae O1 Ogawa serotype. Of 15 water samples, 8 (53%) showed growth of fecal coliforms. Conclusions This laboratory-confirmed cholera outbreak associated with drinking untreated municipal water and lack of knowledge of diarrhea transmission triggered public health action in Bhadola, Delhi.

scholarly journals Molecular characterization reveals involvement of altered el tor biotype Vibrio cholerae O1 strains in cholera outbreak at Hyderabad, India

2011 ◽  
Vol 49 (2) ◽  
pp. 280-284 ◽  
Author(s):  
Ajay Kumar Goel ◽  
Meenu Jain ◽  
Pramod Kumar ◽  
Pennagaram Sarguna ◽  
Meera Bai ◽  
...  
Keyword(s):  
Vibrio Cholerae ◽  
Molecular Characterization ◽  
Cholera Outbreak ◽  
Vibrio Cholerae O1 ◽  
El Tor

scholarly journals Antibiotic Susceptibility Patterns of Vibrio cholerae isolates

2010 ◽  
Vol 49 (179) ◽  
Author(s):  
S D Shrestha ◽  
S Malla ◽  
BR Adhikari ◽  
G Shakya ◽  
SR Basnyat ◽  
...  
Keyword(s):  
Vibrio Cholerae ◽  
Antibiotic Susceptibility ◽  
Clinical History ◽  
Sample Collection ◽  
National Public Health ◽  
Vibrio Cholerae O1 ◽  
Stool Samples ◽  
Antibiotics Susceptibility ◽  
Keywords Antibiotics ◽  
El Tor

INTRODUCTION: Cholera is one of the most common diarrhoeal diseases in Nepal. Etiological agent of cholera is Vibrio cholerae which removes essential body fluids, salts and vital nutrients, which are necessary for life causing dehydration and malnutrition. Emerging antimicrobial resistant is common. The aim of the present study was to determine the antibiotic susceptibility pattern of cholera patients in Nepal. METHODS: All the laboratory works were conducted in the bacteriology section of National Public Health Laboratory, Teku from March to September 2005. During this period a total of 340 stool samples from diarrhoeal patients were collected and processed according to the standard laboratory methods. Each patient suffering from diarrhoea was directly interviewed for his or her clinical history during sample collection. RESULTS: A total of 340 stool samples were processed and studied from both sex including all ages of patients. Among the processed sample 53 Vibrio cholerae cases were found. All isolated Vibrio cholerae O1 were El Tor, Inaba. All isolated (100%) Vibrio cholerae O1 were sensitive to Ampicillin, Ciprofloxacin, Erythromycin and Tetracycline whereas all were resistant to Nalidixic acid and Cotrimoxazole. Only 15.1% cases were sensitive to Furazolidone whereas 84.9% were resistant. CONCLUSION: All V. cholerae strains isolated in this study were found resistant to Multi Drug Resistant (resistant to at least two antibiotics of different group). Ampicillin, Ciprofloxacin, Erythromycin and Tetracycline were found still more potent antibiotics against Vibrio cholerae isolated during the study. Keywords: antibiotics, susceptibility, Vibrio cholera.

scholarly journals A Cholera Outbreak of the Vibrio cholerae O1 El Tor Variant Carrying Classical CtxB in Northeastern Thailand in 2007

2010 ◽  
Vol 82 (5) ◽  
pp. 875-878 ◽  
Author(s):  
Kazuhisa Okada ◽  
Siriporn Chantaroj ◽  
Pathom Sawanpanyalert ◽  
Shigeyuki Hamada ◽  
Amonrattana Roobthaisong
Keyword(s):  
Vibrio Cholerae ◽  
Cholera Outbreak ◽  
Vibrio Cholerae O1 ◽  
El Tor ◽  
Northeastern Thailand

scholarly journals Rugose atypical Vibrio cholerae O1 El Tor responsible for 2009 cholera outbreak in India

2016 ◽  
Vol 65 (10) ◽  
pp. 1130-1136 ◽  
Author(s):  
Goutam Chowdhury ◽  
Rupak K. Bhadra ◽  
Satyabrata Bag ◽  
Gururaja P. Pazhani ◽  
Bhabatosh Das ◽  
...  
Keyword(s):  
Vibrio Cholerae ◽  
Cholera Outbreak ◽  
Vibrio Cholerae O1 ◽  
El Tor
Sign in / Sign up

Export Citation Format

Share Document