scholarly journals Hepatocellular carcinoma in eastern India, a detail analytical report from a tertiary care hospital

Author(s):  
Sudeb Mukherjee ◽  
Kingshuk Dhar ◽  
Suhana Datta ◽  
Apurba Kumar Mukherjee

<p class="abstract"><strong><span lang="EN-US">Background: </span></strong>Hepatocellular carcinoma is the one of the commonest tumour worldwide.  A detailed clinical profile including its etiology and vast presentation is not available in Eastern India.</p><p class="abstract"><strong><span lang="EN-US">Methods: </span></strong>Retrospective chart review of 90 patients with HCCwas done. Total 90 patients (male 81, female9)  fulfillingdiagnostic criteria for HCC adopted by Barcelona-2000 EASL conferencewere analyzed for clinical, etiological, biochemical and radiological profile.</p><p class="abstract"><strong><span lang="EN-US">Results: </span></strong>Underlying cirrhosis was seen in 60% cases with Hepatitis B virus being the most common (33.3%) etiologic agent followed by Alcoholism (26.6%) in cirrhotic range. In 76.7% of HCC patients have AFP level more than 500 unit and practically diagnostic of HCC. Almost all patients presented with advanced disease (96.7%). Only 3.3% of HCC patients presented with mild disease.</p><p class="abstract"><strong><span lang="EN-US">Conclusions: </span></strong>The characteristics of HCC in eastern India are somewhat different from the rest of worlds. Alcohol and HBV infection are the two most important etiology prevailing here. </p><p class="keywords"><strong><span lang="EN-US">Keywords: </span></strong>HCC (Hepatocellular carcinoma), AFP (Alpha fetoprotein), HBV (Hepatitis B virus), HCV (Hepatitis C virus)</p>

2019 ◽  
Vol 25 (1) ◽  
pp. 6-13
Author(s):  
Nahida Zafrin ◽  
M.A. Sattar Sarkar ◽  
Md. Motlabur Rahman ◽  
Umma Salma ◽  
Tania Mahbub ◽  
...  

2004 ◽  
Vol 38 (9) ◽  
pp. e81-e86 ◽  
Author(s):  
P. Vivekanandan ◽  
P. Abraham ◽  
G. Sridharan ◽  
G. Chandy ◽  
D. Daniel ◽  
...  

2019 ◽  
Vol 9 (2) ◽  
pp. 72-78
Author(s):  
Kalpana Sharma ◽  
Sabina Adhikari

Background: Nurses are most vulnerable group for having Hepatitis B Virus (HBV) infection from blood and body fluids. These infections are prevent­able if the nurses have proper knowledge regarding Post Exposure Prophy­laxis (PEP) for hepatitis B virus infections and utilize the PEP services. This study aimed to find out the nurses’ knowledge on PEP for HBV infection. Methods: A descriptive survey design was carried out among 116 random­ly selected nurses working in different wards of tertiary care hospital. Data was collected from July 8th 2018 to 21st July 2018 using pre-tested self-administered questionnaire. Descriptive statistics was used to describe the variables and chi-square test was applied to explore the association between variables. Results: Results of the study revealed that only 22.4% nurses had good, 21.6% had average, and 56.0% had poor knowledge on PEP for HBV. Majority (68.1%) of the nurses knew about the testing of HBsAg serum antigen after exposure. However, few nurses had knowledge on risk per­centage of getting infection (29.3%), contact person for risk assessment (33.6%), constituents of PEP (29.9%), and PEP treatment for unvaccinat­ed/incompletely vaccinated nurse in case of positive (38.8%) and negative (34.5%) sources. Moreover, working unit (p=0.037) and working experi­ence (p=0.027) were the significant variables associated with the level of knowledge on PEP. Conclusions: More than half of nurses’ have poor knowledge on PEP for hepatitis B virus. Hence, there is need of regular in-service education and training for nurses on PEP for HBV to enhance their knowledge and to pre­vent potential infections.


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