scholarly journals Salivary gland tumours: a hospital-based study on demographic and incidence pattern, histopathological types and treatment strategy

2020 ◽  
Vol 6 (12) ◽  
pp. 2218
Author(s):  
M. K. Mili ◽  
Hirak Jyoti Das ◽  
Asha Saikia ◽  
N. J. Saikia ◽  
J. Phookan ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Treatment Strategy ◽  
Tertiary Care ◽  
Minor Salivary Gland ◽  
Salivary Gland Tumour ◽  
Female Ratio ◽  
Salivary Gland Tumours ◽  
Gland Tumour

<p><strong>Background: </strong>Salivary gland tumours constitute 3-4% of all head and neck cancers (mostly benign). These tumours are epithelial (95%) or mesenchymal in origin. Pleomorphic adenoma is the most common benign salivary gland tumour and mucoepidermoid carcinoma (45%) is the most common malignant salivary gland tumour followed by adenoid cystic carcinoma (30%). The parotid, submandibular and the minor salivary glands of palate are commonly involved and the sublingual gland is rarely affected.</p><p><strong>Methods: </strong>Hospital based cross sectional study was done in a tertiary care centre during a period of 1 year, which included 21 patients (10 men and 11 women). Patients were analysed according to age, gender, food habits, histopathological type and site of the tumour and treatment strategy.</p><p><strong>Results: </strong>All the cases were from upper Assam province sharing a particular demographic pattern between 19-65 years. Peak incidence in males was fourth decade and females was third decade. Male female ratio was 0.9:1. Out of 21 cases, 14 were parotid gland tumours, 6 submandibular gland tumours and 1 minor salivary gland tumour. Most of the tumours were benign (16) and 5 were malignant.</p><p><strong>Conclusions: </strong>Two patients were of age 19 years which is conflicting the normal national incidence. All cases belonged to lower economic strata with decreased intake of beta carotene enriched food items. The most common site is parotid gland and most common tumour is pleomorphic adenoma which is in accordance to other studies. Benign cases were subjected to superficial parotidectomy and malignant cases to total parotidectomy with neck dissection.</p>

scholarly journals A clinical study of the incidence of salivary gland tumors in a tertiary care teaching hospital

2019 ◽  
Vol 6 (6) ◽  
pp. 2110
Author(s):  
Sathish Babu N. ◽  
Naveen H. Mahadev ◽  
Kumar G. V.
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Critical Role ◽  
Tertiary Care ◽  
Malignant Neoplasm ◽  
Salivary Gland Tumour ◽  
Major Salivary Gland ◽  
Salivary Gland Tumours ◽  
Gland Tumour

Background: The salivary gland system of the upper aero digestive tract plays a critical role in the functions of digestion, respiration, communication, and overall homeostasis. The Salivary gland swellings can be broadly classified into inflammatory, non-inflammatory and neoplastic swellings like calculi, benign tumours such has pleomorphic adenoma, oncocytoma, Warthin's tumour, malignant tumors which include-adenocarcinoma, adenoid cystic carcinoma, undifferentiated carcinoma.Methods: The present cross-sectional study was conducted at the Department of general surgery, Sri Siddhartha Medical College over a period of 2 years from August 2016 to July 2018.  All major salivary gland neoplastic swellings confirmed by FNAC were included in this study.Results: In our study 23 patients had major salivary gland tumours out of that 19 patients had parotid and 4 had submandibular major salivary gland tumour. In our study out 23 cases of salivary tumours 19 cases were benign and 4 cases were malignant, out of 19 cases of parotid tumours, 15 (78.94%) cases were seen in superficial lobe and 4 (21.06%) were in deep lobe, out of 23 salivary gland tumours, 19 (82.6%) cases were pleomorphic adenoma 3(13.05%) cases were mucoepidermoid carcinoma and one case (4.35%) was acinic cell carcinoma.Conclusions: Parotid gland was the most common site of origin of both benign and malignant tumours, Pleomorphic adenoma was the most common benign salivary gland tumour and mucoepidermoid carcinoma was the most frequent malignant neoplasm.

scholarly journals Salivary gland tumours: a retrospective study at a tertiary care centre in South India

2021 ◽  
Vol 7 (5) ◽  
pp. 825
Author(s):  
Neha Swarnkar ◽  
Srinivasan Venkataraman ◽  
Prasanna Kumar Saravanam
Keyword(s):  
Salivary Gland ◽  
Retrospective Study ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
South India ◽  
Tertiary Care ◽  
Salivary Gland Tumors ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Salivary Gland Tumours

<p><strong>Background:</strong> Salivary gland tumors are morphologically and histologically diverse group of lesions and their frequency varies in several parts of the world. Better understanding of these tumours will help in assessing the behaviour and outcomes of lesions of this region. The aim of this study was to analyse the charactertistics of different tumours occurring in the salivary gland in a tertiary care centre in South India.</p><p class="abstract"><strong>Methods:</strong> A retrospective study was conducted of salivary gland tumors diagnosed from the year 2015 to 2020. Patient age and gender, tumor site and frequency, histopathological diagnosis were evaluated and analysed.</p><p class="abstract"><strong>Results:</strong> A total of 36 salivary gland tumor cases was identified, 30 (87.3%) of which were classified as benign and 6 (12.7%) as malignant. Most tumors occurred in the parotid gland (81.3%). Pleomorphic adenoma was the most common tumor in 23 patients (63.8%), followed by warthins tumour. The tumors occurred more often in women than men.</p><p><strong>Conclusion: </strong>The results of the present study reinforce prevalence of salivary gland tumours. The parotid gland is the most common location and pleomorphic adenoma are the most frequent lesions. The malignant tumors also can occur in these glands and good clinical suspicion is necessary.</p><p class="abstract"> </p>

scholarly journals Clinicopathological study of minor salivary gland tumour

1970 ◽  
Vol 17 (1) ◽  
pp. 48-52
Author(s):  
Md Shazibur Rashid ◽  
Mohammad Ashequr Rahman Bhuiyan ◽  
Mohammad Shafiqul Islam ◽  
Belayat Hossain Siddiquee
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Hard Palate ◽  
Minor Salivary Gland ◽  
Malignant Tumour ◽  
Histological Type ◽  
Salivary Gland Tumour ◽  
Salivary Gland Neoplasm ◽  
Minor Salivary Gland Tumour ◽  
Gland Tumour

Objectives: To find out the clinicopathological factors of minor salivary gland tumour. Methods: An attempt has been made to explore the relative incidence, clinical presentation, age and sex distribution, histological type, site of involvement of each cases of minor salivary gland tumour. Thirty cases of minor salivary gland tumours were studied. Sampling method was purposive, convenient. Data were collected in a prescribed data sheet from BSMMU, DMCH and BKZMC and SSH, Dhaka, during the period of October 2006 to May 2007. Results: In this series of 30 patients, 20 cases (67%) were found malignant and 10 cases (33%) were benign. Regarding the site of distribution of minor salivary gland tumour, 67% (20) were found in the hard palate, three patients were found in the soft palate, three patients in the check, two in the nasopharynx and two in the alveolar margin. All benign tumours in this series were pleomorphic adenoma. Monomorphic adenoma was not found in any patients. Among malignant tumour adenoid cystic carcinoma was the most common 70% (14). Pleomorphic adenoma was found in 33% (10) of total cases. Muco-epidermoid carcinoma was the 2nd most common malignant tumour 12.5% (4). Carcinoma in pleomorphic adenoma was the least common histological type 6% (2). Conclusion: Early diagnosis and treatment of minor salivary gland tumour is likely to lead to a fair outcome. All patients with swelling in hard palate should be considered as a minor salivary tumour. Sub clinical lymphatic metastasis may occur in malignant cases, so all patients should be referred for radiotherapy following surgery. Distant metastases are also rare in such type of malignancy. Key words: Minor salivary gland; Neoplasm. DOI: 10.3329/bjo.v17i1.7628 Bangladesh J Otorhinolaryngol 2011; 17(1): 48-52

scholarly journals Schwannoma-like pleomorphic adenoma of the parotid

Rare Tumors ◽  
2011 ◽  
Vol 3 (4) ◽  
pp. 126-128 ◽  
Author(s):  
Jean-Christophe Tille ◽  
Hervé Reychler ◽  
Marc Hamoir ◽  
Sandra Schmitz ◽  
Birgit Weynand
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Rare Case ◽  
Salivary Gland Tumour ◽  
Frequent Finding ◽  
Chondroid Metaplasia ◽  
Gland Tumour

Pleomorphic adenoma is the most common benign salivary gland tumour. It can occur in any salivary gland, but is most frequently found in the parotid gland. Chondroid metaplasia is a frequent finding in pleomorphic adenoma. Other forms of metaplasia have been described, but are encountered less frequently. We report a rare case of unusual pleomorphic adenoma of the parotid gland with schwannoma-like feature.

scholarly journals Minor Salivary Gland Tumours of Upper Aerodigestive Tract: A Clinicopathological Study

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Grażyna Wyszyńska-Pawelec ◽  
Michał Gontarz ◽  
Jan Zapała ◽  
Mariusz Szuta
Keyword(s):  
Salivary Gland ◽  
Minor Salivary Gland ◽  
Relative Survival ◽  
Aerodigestive Tract ◽  
Malignant Tumours ◽  
Upper Aerodigestive Tract ◽  
Female Ratio ◽  
Salivary Gland Tumours ◽  
Results Of Treatment ◽  
Radial Forearm

The aim of this retrospective study of 56 patients with minor salivary gland tumours (MSGTs) of the upper aerodigestive tract is to present demographic features, distribution of tumours as well as methods and results of treatment performed in our institution over a 10-year period. Of 221 patients with salivary gland tumours, 56 patients with MSGT were selected. There were 36 female and 20 male patients aged from 8 to 81 years. Male-to-female ratio was 1 : 2 in the group of benign MSGT and 1 : 1.7 in the group of malignant tumours. The palate was the most frequent site of MSGT (45.6%), followed by buccal mucosa (19.3%). Of all MSGTs 63.2% were malignant, and 36.8% were benign. Adenoid cystic carcinoma was the most common neoplasm (31.6%), followed by pleomorphic adenoma (29.8%). Surgery was the method of choice in the treatment of patients with MSGT. Postoperative defects were reconstructed by prosthetic obturators, local flaps, and free radial forearm flap. Relative survival for patients with malignant MSGT was 88% at three years and 71.5% at five years. MSGTs are more frequent in females and predominantly affect the palate. Malignant MSGTs are more common than benign.

Kallikrein-related peptidase 10 expression in salivary gland tissues and tumours

2012 ◽  
Vol 27 (4) ◽  
pp. 381-388 ◽  
Author(s):  
Mark R. Darling ◽  
Nelly N. Hashem ◽  
Irene Zhang ◽  
Mohamed Mohamed ◽  
Kevin Fung ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Adenoid Cystic Carcinoma ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Salivary Gland Tumour ◽  
Immunoperoxidase Staining ◽  
Aberrant Expression ◽  
Adenoid Cystic ◽  
Gland Tumour

Objectives Kallikrein-related peptidase 10 (KLK10) has been implicated in the development of several types of cancer. The purpose of this study was to analyze the expression of KLK10 in 3 types of salivary gland tumour and normal salivary glands. Materials and methods: A standard immunoperoxidase staining technique was used to assess the Immunoexpression profile of KLK10 in normal salivary glands and 3 types of salivary gland tumour: pleomorphic adenoma, adenoid cystic carcinoma and mucoepidermoid carcinoma. Results Pleomorphic adenomas showed significantly lower KLK10 levels than control tissues. Neither of the malignant tumours (adenoid cystic carcinoma and mucoepidermoid carcinoma) showed a significant alteration in the immunoreactive scores of KLK10 in comparison with the normal salivary gland tissues. KLK10 immunoreactive scores were comparable in adenoid cystic carcinoma and mucoepidermoid carcinoma. Pleomorphic adenoma had significantly lower levels of KLK10 than mucoepidermoid carcinoma. Conclusions The finding of lower KLK10 levels in pleomorphic adenoma suggests aberrant expression in a tumour that develops primarily from myoepithelial cells. A kallikrein cascade may play a role in the development and/or outcome of some salivary gland tumours.

scholarly journals Salivary gland tumours - a three years experience at King Edward Medical College, Lahore

2016 ◽  
Vol 10 (2) ◽  
Author(s):  
Asmaa Qureshi ◽  
Khalilur Rehman ◽  
Sohail Husain ◽  
Nasirul Hasan Khawaja ◽  
Ghulam Rasood Qureshi ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Single Case ◽  
Malignant Neoplasms ◽  
Salivary Gland Tumours ◽  
Medical College ◽  
Common Location ◽  
Female Predominance

Salivary gland tumours make an important part of oral & maxillofacial pathology. Only few studies have been done in Pakistani population. The aim of this study was to describe morphological types of salivary gland tumours diagnosed at King Edward Medical College/ Mayo Hospital, Lahore during the years 1999-2001 and to compare their demographic data with those previously published. Material & Methods: This descriptive cross-sectional study was carried out at King Edward Medical College/ Mayo Hospital, Lahore. It reports 117 cases of salivary gland tumours diagnosed at Pathology Department during 1999-2001. Results: Of the 128 specimens of salivary glands, 117(91.4%) were confirmed as salivary neoplasms. Out of them, 62.7% were benign and 37.6% malignant and a slight female predominance (58.1%) was found. The most common location was the parotid gland (65.8%) followed by minor salivary glands (19.6%). Majority oft he t tumours was diagnosed during 3rd to 5 decades of life. Median age for benign tumours was 33 years (range 1-78) and a female predominance (58.9%) was seen again. Median age for malignant neoplasms was 45 years (range 9-70) with a female predilection ( 56.8%). However, 4 out o f 5 patients with Warthin`s tumour were men. Pleomorphic adenoma was the most frequent tumour (51.3%), followed by mucoepidermoid carcinoma (25.6%), adenoid cystic carcinoma (7.7)), Warthin`s tumour (4.3%) and monomorphic adenoma (2.6%). Two cases each of oncytoma & adenocarcinoma were recorded. Rare categories (single case each) of salivary tumours included lipoma, acinic cell carcinoma, basal cell adenoma, capillary haemangioma, metastatic carcinoma and non Hodgkin`s lymphoma. Conclusion: The principal site of salivary tumours was the parotid gland and females were most affected. Pleomorphic adenoma was the most frequent finding. The results of this study are comparable with other studies.

Palatal pleomorphic adenoma in a child

1995 ◽  
Vol 109 (4) ◽  
pp. 343-345 ◽  
Author(s):  
A. Noghreyan ◽  
A. Gatot ◽  
E. Maor ◽  
D. M. Fliss
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Hard Palate ◽  
Minor Salivary Gland ◽  
Salivary Gland Tumours ◽  
A Minor ◽  
Benign Salivary Gland Tumours

AbstractBenign salivary gland tumours in childhood are rare. We present a case of a pleomorphic adenoma arising in a minor salivary gland within the hard palate, review the literature and discuss the diagnostic and therapeutic features of the condition.

scholarly journals Clinicopathological profile of adenoid cystic carcinoma of minor salivary gland tumour: our experience at a tertiary care centre

2020 ◽  
Vol 6 (8) ◽  
pp. 1460
Author(s):  
Prakash Mylanahalli Doddrangaiah ◽  
Bharath Kanna Karunakaran ◽  
Roopa S. Mallali ◽  
Afshan Fathima
Keyword(s):  
Salivary Gland ◽  
Adenoid Cystic Carcinoma ◽  
Salivary Glands ◽  
Hard Palate ◽  
Minor Salivary Gland ◽  
Salivary Gland Tumour ◽  
Minor Salivary Glands ◽  
Adenoid Cystic ◽  
Minor Salivary Gland Tumour ◽  
Gland Tumour

<p class="abstract"><strong>Background:</strong> Adenoid cystic carcinoma (ACC) is a rare malignant tumour originating from minor salivary glands. It is known for perineural spread, local recurrences and distant metastasis. The minor salivary gland tumour represents 3% of all head and neck neoplasms, whereas ACC constitutes about 0.5% of all malignant salivary gland neoplasms. This study was done to evaluate the clinical presentation and histopathological findings of minor salivary gland tumour.</p><p class="abstract"><strong>Methods:</strong> This study was done in the department of ENT, Bangalore Medical College and Research Institute from May 2017 to July 2019. Of the 25 patients with minor salivary gland tumour, 10 patients with ACC were considered for the present study. A detailed clinical and histopathological evaluation was done. Results were documented and tabulated in excel sheet.  </p><p class="abstract"><strong>Results:</strong> We analysed data of 25 (16 female, 9 male) patients in the age group of 30-60 years, of which 10 patients had adenoid cystic carcinoma of minor salivary gland tumour. The most frequent site of tumour occurrence was noted in the hard palate (6 patients), followed by retromolar trigone (2 patients), floor of mouth (1 patient) and tongue (1 patient). The histopathological pattern noted most commonly in our study: cribriform pattern (6 cases), tubular (1 case) and solid (3 cases).</p><p class="abstract"><strong>Conclusions:</strong> ACC of minor salivary glands is rare. The otorhinolaryngologist should bear this clinical entity in mind when encountered with a painless swelling over the hard palate. This would lead to an early diagnosis and prompt management in such patients.</p>

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