Retroperitoneal teratoma with malignant somatic transformation: Tumor within a tumor

Extra-gonadal teratomas are rare and occur at various sites with the retroperitoneum being an unusual site. We report a case of an adenocarcinoma arising in a mature retroperitoneal teratoma with bilateral lung metastasis in a young female. Around less than 20 such cases have been reported in literature with the present case being probably second in the Indian scenario and the first to have adenocarcinomatous component matastasize to lungs. We hereby emphasize on the importance of looking for such suspicious areas in a teratoma in order to tailor subsequent management.

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Osteosarcoma of first metacarpal with bilateral lung metastasis: A rare case report

Medical Journal of Dr D Y Patil University ◽

10.4103/0975-2870.218179 ◽

2017 ◽

Vol 10 (5) ◽

pp. 485

Author(s):

Mamta Jain ◽

Rajeev Saxena ◽

Harshvardhan Singh ◽

RP Meena

Keyword(s):

Case Report ◽

Lung Metastasis ◽

Rare Case ◽

Rare Case Report ◽

Bilateral Lung

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Primary primitive neuroectodermal tumor of the adrenal gland: A unique tumor at an unusual site

Indian Journal of Pathology and Oncology ◽

10.18231/j.ijpo.2021.085 ◽

2021 ◽

Vol 8 (3) ◽

pp. 429-432

Author(s):

Rakhi V Jagdale ◽

Jaydeep N Pol

Keyword(s):

Primitive Neuroectodermal Tumor ◽

English Literature ◽

Young Female ◽

Cell Tumor ◽

Neuroectodermal Tumor ◽

Unusual Site ◽

Non Hodgkin Lymphoma ◽

Blue Cell ◽

Neuroectodermal Origin ◽

Round Blue Cell Tumor

Ewing sarcoma/Primitive Neuroectodermal Tumor (ES/PNET) is a malignant small round blue cell tumor of neuroectodermal origin that affects bones and soft tissue in children and young adults. ES/PNET is very uncommon in parenchymal organs. We report a case of primary adrenal PNET in a young female having pregnancy induced persistent hypertension. She underwent right adrenalectomy for a large adrenal mass. On histopathology, it was typical malignant round cell tumor (MRCT). Immunohistochemistry confirmed the diagnosis of ES/PNET with expression of CD99, FLI-1 and NKX2.2. Until now, only 38 cases of primary adrenal ES/PNET have been reported in the English literature with just 5 cases from India. Adrenal ES/PNET can be mistaken with other MRCTs like Non-Hodgkin lymphoma and neuroblastoma. Since the biology, treatment and prognosis of these tumors is entirely different, we emphasize that pathologists must be aware of this possibility and try to differentiate them using ancillary techniques.

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Cardiac Tamponade as an Initial Manifestation of Cervical Cancer

Case Reports in Oncological Medicine ◽

10.1155/2019/7524797 ◽

2019 ◽

Vol 2019 ◽

pp. 1-5

Author(s):

Yuridia Evangelina Rodríguez-Rosales ◽

Carlos Eduardo Salazar-Mejía ◽

Blanca Angélica Soto-Martínez ◽

David Hernández-Barajas ◽

Oscar Vidal-Gutiérrez ◽

...

Keyword(s):

Cervical Cancer ◽

Cardiac Tamponade ◽

Abnormal Uterine Bleeding ◽

Young Female ◽

Pericardial Fluid ◽

Unusual Site ◽

Initial Manifestation ◽

Gynecological Examination ◽

Appropriate Treatment ◽

Leg Edema

Cervical cancer is the second most common malignancy worldwide in women and the third most common cause of cancer death in developing countries. This type of cancer spreads mainly to the lung, the bone, and the brain; however, the pericardium is an unusual site of invasion, which is associated with a poor prognosis. We present a case of a 35-year-old woman with six months of leg edema and abnormal uterine bleeding. During the initial evaluation, cardiac tamponade and a bilateral pleural effusion were found. A left supraclavicular lymphadenopathy was identified on physical examination, while gynecological examination and MRI were irrelevant. Initial cytology of the pericardial fluid showed a poorly differentiated carcinoma, and a cervical biopsy revealed a squamous cell invasive carcinoma. Chemotherapy was started with carboplatin and paclitaxel, but no clinical improvement was noted and the patient died 46 days after arrival. Cardiac tamponade in a young female patient is a harbinger to widen the differential diagnosis to include not only infectious, cardiac, or metabolic etiology but also oncological causes since this will allow appropriate treatment.

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Hemorrhagic brain metastasis from osteogenic sarcoma of iliac bone in young female: Unusual site of presentation

Neurology India ◽

10.4103/0028-3886.84361 ◽

2011 ◽

Vol 59 (4) ◽

pp. 639 ◽

Cited By ~ 1

Author(s):

AmitN. D Dwivedi ◽

Kumkum Gupta ◽

PrashantK Gupta ◽

Gouri Garg

Keyword(s):

Brain Metastasis ◽

Osteogenic Sarcoma ◽

Young Female ◽

Iliac Bone ◽

Unusual Site

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Primary Carcinosarcoma of Ovary with Lung Metastasis in a Young Female: A Rare Case Report

MOJ Clinical & Medical Case Reports ◽

10.15406/mojcr.2016.05.00129 ◽

2016 ◽

Vol 5 (2) ◽

Author(s):

Kafil Akhtar

Keyword(s):

Case Report ◽

Lung Metastasis ◽

Rare Case ◽

Young Female ◽

Rare Case Report

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Melanoma of Urinary Bladder presented as acute urine retention

Nepalese Journal of Cancer ◽

10.3126/njc.v1i1.25637 ◽

2017 ◽

Vol 1 (1) ◽

pp. 67-70

Author(s):

Nirmal Lamichhane ◽

Hari P. Dhakal

Keyword(s):

Urinary Bladder ◽

Urinary Diversion ◽

Lung Metastasis ◽

Bladder Outlet Obstruction ◽

Outlet Obstruction ◽

Urine Retention ◽

Suprapubic Cystostomy ◽

Acute Urine Retention ◽

Bilateral Lung ◽

Time Of Presentation

This report is of a 50-year-old man with a rare urinary bladder melanoma. He presented with hematuria followed by bladder outlet obstruction at the time of presentation. Ultrasonogram of the pelvis revealed a mass in the bladder outlet, suggestive of enlarged prostate. Suprapubic cystostomy was then performed. Subsequent transvesical exploration revealed a dark coloured mass at the outlet of bladder, which on histopathology confirmed to be melanoma. After ruling out other possible primary sites, he underwent radical cysto-urethrectomy with urinary diversion. Disease was confirmed with immunohistochemistry. Patient died after 3 months with bilateral lung metastasis.

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Effectiveness of intraoperative bimanual palpation in metastatic tumors of lung

Turkish Journal of Thoracic and Cardiovascular Surgery ◽

10.5606/tgkdc.dergisi.2020.20429 ◽

2020 ◽

Vol 28 (4) ◽

pp. 662-668

Author(s):

Bülent Mustafa Yenigün

Keyword(s):

Computed Tomography ◽

Lung Metastasis ◽

Complete Resection ◽

Pulmonary Metastasectomy ◽

Metastatic Tumors ◽

Thoracic Computed Tomography ◽

Bimanual Palpation ◽

Study Results ◽

Muscle Sparing ◽

Bilateral Lung

Background: In this study, we aimed to compare effectiveness of thoracic computed tomography versus intraoperative bimanual palpation in the detection of number of nodules in patients undergoing thoracotomy. Methods: Between January 2011 and January 2019, a total of 157 patients (63 males, 94 females; mean age: 46.6±11.2 years; range, 13 to 77 years) who underwent pulmonary metastasectomy in our institution were retrospectively analyzed. Metastatic nodules evaluated using thoracic computed tomography were compared with nodules detected by intraoperative palpation. Results: A total of 226 muscle-sparing thoracotomy was performed in 157 patients. The time between the preoperative thoracic computed tomography and operation ranged from 3 to 24 days. Metastasectomy with muscle-sparing thoracotomy was performed in 41 (26%) patients two times, in eight (5%) patients three times, and in four (2.5%) patients four times due to bilateral lung metastasis or re-metastasectomy. The thoracic computed tomography could detect 476 metastatic nodules, while 1,218 nodules were palpated and resected intraoperatively. Of these nodules, 920 were pathologically evaluated as metastatic. Conclusion: Our study results showed that the number of nodules reported as pathologically malignant after resection was 1.9 times higher than those reported by thoracic computed tomography. This finding indicates that intraoperative bimanual examination significantly increases the possibility of complete resection. This situation raises the need for more caution for the thoracoscopic metastasectomy procedure in which there is no possibility of intraoperative bimanual palpation.

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