scholarly journals Angiomyolipoma of the Oral Cavity: A Rare Case Report

2019 ◽  
pp. 107-110
Author(s):  
Sara Amanpour ◽  
Mohammad Reza Zarei ◽  
Javad Faryabi ◽  
Ahmad Ahrari
Keyword(s):  
Oral Cavity ◽  
Giant Cell ◽  
Case Reports ◽  
Thick Wall ◽  
Giant Cell Granuloma ◽  
First Case ◽  
Peripheral Giant Cell Granuloma ◽  
Rare Case Report ◽  
Rare Benign Tumor ◽  
Local Trauma

Angiomyolipoma (AML) is a rare, benign tumor composed of thick-wall blood vessels, smooth muscle component and mature adispose tissue. Differentiation from other benign and malignant mesenchymal lesions of oral cavity depends on recognition of these three histologic components, and immunohistochemical (IHC) techniques are also helpful. This tumor arise from perivascular epithelioid cells (PEComas) and kidneys followed by liver are the main locations of this soft tissue tumor. AMLs are rarely found in oral cavity and few case reports of oral AML have been reported in the literature. We report the first case of concurrent occurrence of AML of the tongue and peripheral giant cell granuloma of the gingiva in a 59-year-old patient. Clinically it was presented as a painless nodular mass with a smooth surface on the dorsal of the tongue. Based on histopathologic features and IHC staining the diagnosis of oral AML was done. The other lesion was a small sessile mass in interdental papillae of the lower incisors and microscopic examination showed the histologic features of a peripheral giant cell granuloma. Concurrent occurrence of PGCG which is a reactive mucosal hyperplasia and AML in our patient, could show the probable role of local trauma in the pathogenesis of these lesions.

scholarly journals Massive peripheral giant cell granuloma associated with pregnancy

2016 ◽  
Author(s):  
Vikas Jain
Keyword(s):  
Oral Cavity ◽  
Giant Cell ◽  
Ovarian Hormones ◽  
Contributory Factor ◽  
Hormonal Changes ◽  
Giant Cell Granuloma ◽  
Young Females ◽  
Peripheral Giant Cell Granuloma ◽  
Nodular Lesions

Peripheral giant cell granuloma (PGCG) is a relatively Common reactive exophytic lesion of the oral cavity. The influence of hormones has been suggested as contributory factor in PGCG development and predominance of these lesions in young females as well as some previously reported pregnancy related cases support this belief. It has been observed that majority of lesions present in the 4th decade of life, when hormonal changes are more pronounced. Cailluette and Mattar in their study found that peripheral giant cell granuloma are under the influence of the ovarian hormones. However Chambers and Spector suggested peripheral giant cell granuloma to be enhanced by pregnancy rather than being pregnancy dependent. The responsiveness of gingiva to these hormones along with the immunosuppressive actions of the hormones contributes to the growth of the lesion. Clinically, PGCGs may present as polypoid or nodular lesions, predominantly bluish red with a smooth shiny or mamillated surface.This poster will review the literature available on the association of Massive Peripheral Giant Cell Granuloma With Pregnancy with focus on possible causes of PGCG during pregnancy.

scholarly journals Coexistence of hyperparathyroidism and peripheral giant cell granuloma of the jaw: A rare case report

2020 ◽  
Vol 9 (6) ◽  
pp. 3142 ◽  
Author(s):  
Naina Pattnaik ◽  
JagadishP Rajguru ◽  
SamarjeetJ Pattanaik ◽  
Debajyoti Bardhan ◽  
Bikash Nayak ◽  
...  
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Rare Case ◽  
Giant Cell Granuloma ◽  
Peripheral Giant Cell Granuloma ◽  
Rare Case Report

scholarly journals Peripheral Giant Cell Granuloma: A Case Report with Review on Its Histogenesis and Recurrence

2019 ◽  
Vol 07 (02) ◽  
pp. 095-098
Author(s):  
Deepti Garg Jindal ◽  
Sandhya Singh Kushwaha ◽  
Sonia Joshi ◽  
Namita Sepolia ◽  
Varun Jindal ◽  
...  
Keyword(s):  
Case Report ◽  
Oral Cavity ◽  
Giant Cell ◽  
Growth Potential ◽  
Biological Behavior ◽  
Ossifying Fibroma ◽  
Giant Cell Granuloma ◽  
Cell Hyperplasia ◽  
High Tendency ◽  
Peripheral Giant Cell Granuloma

AbstractGiant cell granulomas (GCGs) of the jaws are non-neoplastic lesions that arise either peripherally in periodontal ligament, mucoperiosteum, or centrally in the bone. Histologically, both peripheral and central giant cell granuloma are characterized by the presence of numerous multinucleated giant cells in a prominent fibrous stroma. Peripheral giant cell granuloma is an infrequent reactive, exophytic lesion of the oral cavity, also known as giant-cell epulis, osteoclastoma, giant cell reparative granuloma, or giant cell hyperplasia. It is the most common giant cell lesion of the jaws and originates from the connective tissue of the periosteum or from the periodontal membrane, in response to local irritation or chronic trauma. The lesion develops mostly in adults, commonly in the lower jaw, with slight female predilection although is uncommon in children. Clinically, it shows resemblance to pyogenic granuloma, peripheral ossifying fibroma, and many other peripheral lesions seen in the oral cavity, but in our case it resembled a squamous cell carcinoma, thereby histopathology is mandatory for the diagnosis of this lesion. The lesion although being relatively common, still has a lot of ambiguity. The ambiguity is in terms of its etiology, growth potential, biological behavior (recurrence), histogenesis of its cells, and its treatment. The entity further holds significance because of its notorious behavior and high tendency to recur. This is a case report of a 30-year-old female patient with history of swelling in the lower anterior region of jaw since 1 year. After complete excision of lesion, lesion reoccurred after few months.

scholarly journals Pyogenic Granuloma/Peripheral Giant-Cell Granuloma Associated with Implants

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Enric Jané-Salas ◽  
Rui Albuquerque ◽  
Aura Font-Muñoz ◽  
Beatríz González-Navarro ◽  
Albert Estrugo Devesa ◽  
...  
Keyword(s):  
Giant Cell ◽  
Successful Treatment ◽  
Case Reports ◽  
Pyogenic Granuloma ◽  
Relevant Information ◽  
Cochrane Library ◽  
Giant Cell Granuloma ◽  
National Library ◽  
Level Of Evidence ◽  
Peripheral Giant Cell Granuloma

Introduction. Pyogenic granuloma (PG) and peripheral giant-cell granuloma (PGCG) are two of the most common inflammatory lesions associated with implants; however, there is no established pathway for treatment of these conditions. This paper aims to illustrate the successful treatment of PG and PGCG and also report a systematic review of the literature regarding the various treatments proposed.Methods. To collect relevant information about previous treatments for PG and PGCG involving implants we carried out electronic searches of publications with the key words “granuloma”, “oral”, and “implants” from the last 15 years on the databases Pubmed, National Library of Medicine’s Medline, Scielo, Scopus, and Cochrane Library.Results. From the electronic search 16 case reports were found showing excision and curettage as the main successful treatment. As no clinical trials or observational studies were identified the authors agreed to present results from a review perspective.Conclusion. This is the largest analysis of PG and PGCG associated with implants published to date. Our review would suggest that PGCG associated with implants appears to have a more aggressive nature; however the level of evidence is very limited. Further cohort studies with representative sample sizes and standard outcome measures are necessary for better understanding of these conditions.

Hybrid peripheral giant cell granuloma and peripheral ossifying fibroma lesion: A rare case report and review of the literature

2017 ◽  
Vol 29 (6) ◽  
pp. 587-593
Author(s):  
Mayara Santos de Castro ◽  
Clenivaldo Alves Caixeta ◽  
Eduardo Pereira Guimarães ◽  
Alessandro Antônio Costa Pereira ◽  
Felipe Fornias Sperandio ◽  
...  
Keyword(s):  
Case Report ◽  
Giant Cell ◽  
Rare Case ◽  
Ossifying Fibroma ◽  
Giant Cell Granuloma ◽  
Review Of The Literature ◽  
Peripheral Ossifying Fibroma ◽  
Peripheral Giant Cell Granuloma ◽  
Rare Case Report

Incidence of Peripheral Giant Cell Granuloma in the Oral Cavity: a Retrospective Study

2018 ◽  
Vol 126 (3) ◽  
pp. e161
Author(s):  
Matheus Ambrosio F.M. Dos Santos ◽  
Daniela Nascimento Silva ◽  
João Paulo Santana Favero ◽  
Tânia Regina Grão Velloso ◽  
Martha Alayde Alcantara Salim ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Oral Cavity ◽  
Giant Cell ◽  
Giant Cell Granuloma ◽  
Peripheral Giant Cell Granuloma

scholarly journals Giant-cell granuloma: 2 case reports

2018 ◽  
Vol 24 (4) ◽  
pp. 182-186
Author(s):  
Samir Abdelqader ◽  
Nicolas Roche ◽  
Laurent Manfredi ◽  
Jean-François Papon ◽  
Louis Maman ◽  
...  
Keyword(s):  
Giant Cell ◽  
Kidney Failure ◽  
Case Reports ◽  
Osteolytic Lesion ◽  
Systemic Disease ◽  
Excisional Biopsy ◽  
Bone Lesions ◽  
Giant Cell Granuloma ◽  
First Case ◽  
Osteoclastic Resorption

Introduction: Giant-cell granuloma (GCG) is a benign tumor occurring almost exclusively in the jaws. These lesions remain rare but can sometime have an aggressive behavior. In this article, we will describe and follow two cases of GCG. Observations: The first case is a referred female patient, who presents a mandibular swelling. Its clinical and radiological aspects lead us to do a biopsy, with a histological result of GCG. The second case is a patient with a terminal kidney failure, referred for a buccal swelling in the upper left jaw. The cone-beam computed tomography X-ray shows a compartmentalized lesion with blurry limits. An excisional biopsy is performed and the histological diagnosis is a GCG. Discussion: Although the first patient suffers from no systemic disease, the second one presents a terminal kidney failure resulting in a chronic hyperparathyroidism. Hyperparathyroidism can activate osteoclastic resorption and create bone lesions such as brown tumors. Conclusion: The slow and asymptomatic growth of these lesions often result in a late diagnosis. It should be kept in mind as a differential diagnosis when dealing with an osteolytic lesion of the jaws with no clear etiology, especially if hyperparathyroidism or kidney failure is associated.

scholarly journals Clinical and surgical management of peripheral giant cell granuloma

2017 ◽  
Vol 19 (1) ◽  
Author(s):  
Patricia Vieyra Aranda ◽  
Patricia Trejos Quiroz ◽  
Claudia De León Torres ◽  
Daniela Carmona Ruiz
Keyword(s):  
Oral Cavity ◽  
Giant Cell ◽  
Surgical Management ◽  
Alveolar Bone ◽  
Giant Cells ◽  
Giant Cell Granuloma ◽  
Peripheral Giant Cell Granuloma ◽  
The Right

SUMMARYThe peripheral giant cell granuloma is anexophytic lesion developing in the oral cavity;it is one of the “reactive hyperplasias”The etiology is unknown In the literatureonly 12 cases have been reported in children,in these patients, it achieved rapidgrowth, behaving in an aggressive manneras it absorbed alveolar bone, leading totooth mobility and interferes with eruption.This article presents the case of a male 9years, 6 months old patient, who showeda red, soft, irregularly shaped gingivalswelling involving the right maxillarypremolars of 4cm in diameter with an ulcerin the oclusal side, asymptomatic and withshort evolution. Recurrence appeared inless than 6 months; histopathologic diagnosiswas peripheral giant cell granuloma,the treatment was surgical. The purpose ofthis study was to identify the peripheralgiant cell granuloma to avoid destructionof the alveolar bone, thus avoiding the lossof permanent teeth.Key words: Reactive hyperplasias, granuloma,giant cells.

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