scholarly journals p53 codon 72 polymorphism in cervical cancer patients and healthy women from Poland.

2000 ◽  
Vol 47 (4) ◽  
pp. 1179-1182 ◽  
Author(s):  
A Dybikowska ◽  
A Dettlaff ◽  
K Konopa ◽  
A Podhajska
Keyword(s):  
Cervical Cancer ◽  
Cancer Patients ◽  
Squamous Carcinoma ◽  
Control Group ◽  
P53 Codon 72 ◽  
Codon 72 ◽  
Healthy Women ◽  
Codon 72 Polymorphism ◽  
P53 Codon 72 Polymorphism

A polymorphism at codon 72 of gene p53 results in the presence of either arginine or proline at this position. We investigated the distribution of p53 codon 72 polymorphism in cervical cancer patients and a control group of healthy women from Poland. Our results do not confirm the hypothesis that the p53 codon polymorphism could play a role as a factor for squamous carcinoma of the cervix.

scholarly journals Effect of p53 codon 72 polymorphism on the survival outcome in advanced stage cervical cancer patients in India

2016 ◽  
Vol 144 (3) ◽  
pp. 359 ◽  
Author(s):  
Rita Mulherkar ◽  
Akanksha Bansal ◽  
Poulami Das ◽  
Sadhana Kannan ◽  
Umesh Mahantshetty
Keyword(s):  
Cervical Cancer ◽  
Cancer Patients ◽  
Survival Outcome ◽  
Advanced Stage ◽  
P53 Codon 72 ◽  
Codon 72 ◽  
Codon 72 Polymorphism ◽  
P53 Codon 72 Polymorphism

P53 CODON 72 POLYMORPHISM IN IRANIAN LUNG CANCER PATIENTS

CHEST Journal ◽  
2005 ◽  
Vol 128 (4) ◽  
pp. 331S
Author(s):  
Mehrnoosh Doroudchi ◽  
Seid Mohammad A. Ghayoomi ◽  
Abdulmohammad Pezeshki ◽  
Mohammad J. Fattahi ◽  
Abbas A. Ghaderi
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
P53 Codon 72 ◽  
Codon 72 ◽  
Lung Cancer Patients ◽  
Codon 72 Polymorphism ◽  
P53 Codon 72 Polymorphism

Prognostic value of P53 codon 72 polymorphism in invasive cervical cancer in Brazil

2004 ◽  
Vol 93 (2) ◽  
pp. 374-380 ◽  
Author(s):  
S BRENNA ◽  
I SILVA ◽  
L ZEFERINO ◽  
J PEREIRA ◽  
E MARTINEZ ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Prognostic Value ◽  
Invasive Cervical Cancer ◽  
P53 Codon 72 ◽  
Codon 72 ◽  
Codon 72 Polymorphism ◽  
P53 Codon 72 Polymorphism

Polymorphism of p53 Codon 72 Gene on Cervical Cancer Incidence in Malay Population

2020 ◽  
Vol 1 (1) ◽  
pp. 25-30
Author(s):  
Lusia Hayati ◽  
Siska Delvia
Keyword(s):  
Cervical Cancer ◽  
Control Group ◽  
Case Group ◽  
P53 Codon 72 ◽  
Codon 72 ◽  
Codon 72 Polymorphism ◽  
Significant Difference ◽  
Malay Population ◽  
And Control

In Indonesia, the cases of cervical cancer are estimated at around 50 per 100.000 people. It wasestimatedthattherearemore than1 millionwomenworldwidewho have cervical cancer,andmostofthemhavenot been diagnosed yet or do not have access to screening and medical treatment. P53 codon 72polymorphism can affect the risk of cervical cancerthrough the regulationofproliferationandcellapoptosis.Thepurpose of this research was to investigate the association between p53 codon 72 polymorphism and cases ofcervical cancer. This research was observational analytic research. The research was done by examining in thelaboratory of Molecular Biology, Faculty of Medicine, Universitas Sriwijaya by using a case-control studyapproach.Thesampleoftheresearchconsistedof 70subjects,andtheyweredividedintotwogroups:35in casegroup and 35 in the control group. The determination of genotype and allotype was done by using PCR-RFLPtechnics. The results of the research showed there was a significant difference between p53 codon 72polymorphism between the case group and control group. The results of genotypes of p53 codon 72polymorphism in the case group were seven respondents (20.0%) with Pro/Pro genotype, five respondents(14.3%) with Arg/Arg genotype, and 23 respondents (65.7%) with Pro/Arg. While in control group, there were 28respondents (80.0%) with Pro/Pro genotype, 0 respondent (0.0%) with Arg/Arg genotype, and 7 respondents(20%) with Pro/Arg. The frequency of the Prolin allele in case group was 37 (52.9%), and the Arginin allele was 33(47.1%), while the frequency of the Prolin allele in the control group was 63 (90%), and the Arginin allele was 7(10%).TheChi-Squareofgenotypewas valued0.000,OR1,304andCI95%1,071-5,891,whiletheallelewas valued0.000,OR8.027 andCI95% 3.228-19.962. Therewas an associationbetweengenotypeand allele of p53 codon72polymorphismandcasesofcervicalcancer

Codon 72 polymorphism of p53 in Israeli Jewish cervical cancer patients and healthy women

2002 ◽  
Vol 12 (6) ◽  
pp. 741-744 ◽  
Author(s):  
S. Arbel-Alon ◽  
J. Menczer ◽  
N. Feldman ◽  
M. Glezerman ◽  
L. Yeremin ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Patients ◽  
Codon 72 ◽  
Healthy Women ◽  
Codon 72 Polymorphism

Association of p53 codon 72 polymorphism and survival of North Indian lung cancer patients treated with platinum-based chemotherapy

2016 ◽  
Vol 43 (12) ◽  
pp. 1383-1394 ◽  
Author(s):  
Ankita Kumari ◽  
Charu Bahl ◽  
Navneet Singh ◽  
Digambar Behera ◽  
Siddharth Sharma
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
P53 Codon 72 ◽  
Codon 72 ◽  
Lung Cancer Patients ◽  
Codon 72 Polymorphism ◽  
Platinum Based Chemotherapy ◽  
P53 Codon 72 Polymorphism

scholarly journals p53 Codon 72 Polymorphism and Risk of Cervical Cancer

2003 ◽  
Vol 36 (2) ◽  
Author(s):  
JOSÉ M OJEDA ◽  
SANDRA AMPUERO ◽  
PATRICIO ROJAS ◽  
RODRIGO PRADO ◽  
JORGE E ALLENDE ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
P53 Codon 72 ◽  
Codon 72 ◽  
Codon 72 Polymorphism ◽  
P53 Codon 72 Polymorphism
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