Synthesis of a quaternary polyprenyl ammonium salt.
Keyword(s):
Reaction of primary C(55)-allylic alcohol moraprenol (WT(3)C(7-9)-OH, a polyprenol from mulberry leaves) with triethylamine in the presence of phosphorus oxychloride leads to a quaternary ammonium chloride with a good yield (72%) and high cis-stereoselectivity of the terminal isoprene unit. Cationic polyprenyl derivatives may be useful for transfection and immunological studies.
2007 ◽
Vol 25
(1)
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pp. 63-72
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1972 ◽
Vol 24
(6)
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pp. 859-863
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1973 ◽
Vol 25
(2)
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pp. 253-256
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2017 ◽
Vol 9
(9)
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pp. 1338-1345
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