scholarly journals A Clinical Study on CT Scan Findings in the Diagnosis of Blunt Injuries Abdomen

2020 ◽  
Vol 7 (32) ◽  
pp. 1606-1611
Author(s):  
Jose Kuruvilla ◽  
Sunil M
Keyword(s):  
Clinical Study ◽  
Ct Scan ◽  
Blunt Injuries

Nasal and Sinus Manifestations of Sarcoidosis

2000 ◽  
Vol 14 (3) ◽  
pp. 157-162 ◽  
Author(s):  
Jill F. Zeitlin ◽  
Thomas A. Tami ◽  
Robert Baughman ◽  
Donna Winget
Keyword(s):  
Clinical Study ◽  
Ct Scan ◽  
Additional Patient ◽  
Term Therapy ◽  
Oral Antibiotics ◽  
Sinus Disease ◽  
Nasal Symptoms ◽  
Nasal Steroids ◽  
Long Term Therapy

Nasal and sinus diseases are considered uncommon manifestations of sarcoidosis. We evaluated 159 consecutive patients with sarcoidosis for nasal symptoms. Sixty-three patients (39%) denied any nasal symptoms. Thirty-six patients (23%) had intermittent symptoms that lasted less than three weeks and required continuous intervention with nasal steroids or normal saline. Sixty patients (38%) were treated with nasal steroids and antibiotics for symptoms that lasted more than three weeks. Thirty-three patients (21%) had resolution of their symptoms after treatment with nasal steroids and antibiotics. Twenty-seven patients (17%) had symptoms that were unresponsive to three weeks of oral antibiotics and nasal steroids, and underwent CT scan. Based on the CT results, five patients underwent biopsy, which confirmed sarcoidosis. An additional patient who had a normal CT scan underwent a biopsy that was consistent with sarcoidosis. A retrospective review of 733 sarcoidosis patients was then performed, and an additional 12 patients were identified with biopsy-proven sarcoidosis. All of these patients required long-term therapy with prednisone (14 patients), methotrexate (13 patients), and/or azathioprine (8 patients). Our clinical study reveals a higher incidence of nasal and sinus disease in patients with sarcoidosis than has previously been described, and the recalcitrance of sarcoidosis when there is sinus involvement.

scholarly journals Clinical Study of Intensive Delayed Operation in Aneurysmal Patients with Fisher 3 Group on CT Scan

1991 ◽  
Vol 19 (2) ◽  
pp. 194-197
Author(s):  
Kogo TAKAMIYA ◽  
Masahiro YONEKURA ◽  
Naoki KITAGAWA ◽  
Tadayoshi MORIYAMA ◽  
Shigeyoshi TERAMOTO
Keyword(s):  
Clinical Study ◽  
Ct Scan

TricOsTM and Fibrin Sealant Combined for Bone Defect Filling: from Pre-Clinical Tests to Prospective Clinical Study. Preliminary Human Data

2007 ◽  
Vol 361-363 ◽  
pp. 1335-1338 ◽  
Author(s):  
Marlene Durand ◽  
Dominique Chauveaux ◽  
Maryse Moinard ◽  
Thierry Fabre ◽  
Jean Louis Rouvillain ◽  
...  
Keyword(s):  
Clinical Study ◽  
Ct Scan ◽  
Fibrin Sealant ◽  
Bone Substitute ◽  
Material Removal ◽  
Bone Defects ◽  
Tibial Osteotomy ◽  
Clinical Tests ◽  
X Ray

The association of TricOsTM (Macroporous Biphasic Ceramic Phosphate MBCP granules) and the fibrin sealant FS VH S/D 4, has been developed to answer a challenging request of orthopaedic surgeons: a biocompatible, osteogenic, mouldable, and self-hardening bone substitute able to fill randomly shaped bone defects. The aims of this study was the evaluation of the performance and safety of the bioactive bone substitute TricOs™ associated with a fibrin sealant in regeneration of functional bone. The pre-clinical tests were conducted to optimize MBCP granules size and ratio MBCP–FS VH S/D 4 (sheep maxillary sinus grafting, femoral epiphysis defect in rabbits, long bone defects in sheep). A clinical study design was set up as an exploratory prospective French multicentric phase II study sponsored by INSERM (Institut National de la Santé et de la Recherche Médicale). The application was the TOV (Tibial Osteotomy of Valgisation) using osteosynthesis and bone substitute: TricOs™ mixed with the fibrin sealant (FS VH S/D 4) for filling the space created. The follow up is 13 months with safety checks, clinical assessments, highsensitivity X-ray, and CT-scan imaging. A bone sample will be collected from the reconstructed area at 12 months, during the osteosynthesis material removal surgery. The principal criterion is CT-scan imaging performed 12 months after TOV surgery, before material removal, to assess qualitative and quantitative bone reconstruction. Animals’ studies demonstrate that the biomaterial is safe to use and shows osteoconductive properties, granules resorption and bone ingrowth at the expenses of the implants. As for clinical trial, 7 patients are today included in the study: This paper present the first results obtained from X-ray imaging during follow up.

Bioceramic and Fibrin Sealant in High Tibial Valgus Osteotomy: Prospective Clinical Study

2013 ◽  
Vol 587 ◽  
pp. 381-386
Author(s):  
Daculsi Guy ◽  
Jean Louis Rouvillain ◽  
Thierry Fabre ◽  
Yves Catonné ◽  
Maurice Bagot d'Arc ◽  
...  
Keyword(s):  
Clinical Study ◽  
Ct Scan ◽  
Fibrin Sealant ◽  
Bone Substitute ◽  
Bone Ingrowth ◽  
High Sensitivity ◽  
Prospective Clinical Study ◽  
Tibial Osteotomy ◽  
X Ray

The association of Micro Macroporous Biphasic Calcium Phosphate granules and t fibrin sealant has been developed to answer a challenging request of orthopaedic surgeons: a biocompatible, osteogenic, mouldable, and self-hardening bone substitute able to fill bone defects. The aim of this study was the evaluation of the performance and safety of the bioactive composite in regeneration of functional bone. A clinical study design was set up as an exploratory prospective French multicentric phase II study sponsored by INSERM. The application was the HTVO (Tibial Osteotomy of Valgisation) using osteosynthesis and bone substitute (BS) for filling the space created. The follow up was 12 months with safety checks, clinical assessments, high-sensitivity X-ray, and CT-scan imaging. A bone sample was collected from the reconstructed area at 12 months. 13 patients with stage I gonarthrosis have been included in the study. This clinical follow up revealed only one case of correction loss. X-ray and CT-scan imaging indicated a progressive disappearance of the peripheric radioluency and a decrease of the radiopacity of the implanted area due to bioceramic resorption and bone ingrowth at the expense of the implant. Histological analysis revealed BS large resorption and bone ingrowth both into the pores and at the expense of the bioceramic. X-Ray and micro CT scan revealed a well organised and mineralised structure in the newly-formed bone.

scholarly journals A clinical study of cerebral venous thrombosis

2017 ◽  
Vol 4 (5) ◽  
pp. 1236
Author(s):  
Priyadarsini Bose ◽  
Jacinth Preethi Joshua ◽  
Murali Thandavarayan
Keyword(s):  
Clinical Study ◽  
Magnetic Resonance ◽  
Venous Thrombosis ◽  
Ct Scan ◽  
Cerebral Venous Thrombosis ◽  
Clinical Symptoms ◽  
Sinus Thrombosis ◽  
Transverse Sinus ◽  
Prospective Clinical Study ◽  
Female Ratio

 Background: Cerebral venous thrombosis (CVT) is an uncommon form of stroke, usually affecting young population. Clinical features of CVT are diverse, and for this reason, high degree of clinical suspect is mandatory to diagnose the conditions. The objectives of the study were to analyse the commonest clinical modes of presentation, possible etiologies, and to evaluate clinical outcome.Methods: This study was prospective, clinical study was conducted on 40 patients during the period of September 2010 to September 2011 in the Department of Emergency, Institute of Internal medicine at Government General Hospital (GGH), Chennai. All the patients included in the study were subjected to neuroimaging techniques like Computed tomography (CT), magnetic resonance imaging (MRI) along with magnetic resonance venography (MRV) according to guidelines and standard protocol.Results: Majority of the patients involved in the study were in the age group of 15-35 years contributing to 75%. Male: female ratio was 1.5: 1. Headache was the most common presenting symptom seen in 36 (87.5%) cases followed by convulsions in 32 (80%) patients. Altered sensorium was observed in 26 (65%), focal deficits in 22 (55%), and 18 (45%) had fever. Two of them had ear discharge and another with diarrhea. Cranial nerve involvement in 35% and pappiledema was noted in 20% of patients. Out of 40, 17 (42.5%) patients were anemic. Eighteen (18) patients who were suspected of meningitis underwent CSF analysis. Abnormality was seen in 10 patients with pleocytosis being the maximum. On CT scan, haemorrhagic infarct was seen in 22 (55%) cases followed by edema in 8 (20%) and 10% showed normal CT picture. On MRI scan, superior sagittal sinus thrombosis was observed in 24 (60%) patients followed by transverse sinus in 20 (50%) patients. Etiology factor were identified in 25 (62.5%) of patients and in 15 (37.5%) cases risk factors could not be identified. The mortality rate in the study was 20%.Conclusions: The clinical symptoms of CVT are not specific, as a result of chances of misdiagnosis tends to be more. CT scan and MRI along with MRV can improve the precision of CVT diagnosis.

A Clinical Study of Twenty-seven Children Exhibiting Functional Hearing Loss

1981 ◽  
Vol 12 (1) ◽  
pp. 26-35 ◽  
Author(s):  
Donald L. McCanna ◽  
Giacinto DeLapa
Keyword(s):  
Hearing Loss ◽  
Clinical Study ◽  
Early Identification ◽  
Behavioral Responses ◽  
Upper Elementary ◽  
Elementary Grades ◽  
Ability Level ◽  
Hearing Problem

This report reviews 27 cases of children exhibiting functional hearing loss. The study reveals that most students were in the upper elementary grades and were predominantly females. These subjects were functioning below their ability level in school and were usually in conflict with school, home, or peers. Tests used were selected on the basis of their helping to provide early identification. The subjects' oral and behavioral responses are presented, as well as ways of resolving the hearing problem. Some helpful counseling techniques are also presented.

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