A Cross-Sectional Study of Microcirculatory Transit Time as a Risk Stratification Method in Cardiac Syndrome X Conducted in a Tertiary Hospital at Hyderabad, Telangana

2021 ◽  
Vol 8 (28) ◽  
pp. 2509-2513
Author(s):  
Krishna Malakondareddy Parvathareddy ◽  
Jagadeesh Reddy Kolli ◽  
Srinivas Ravi ◽  
Praveen Nagula ◽  
Syed Imamuddin ◽  
...  
Keyword(s):  
Transit Time ◽  
Cross Sectional Study ◽  
Syndrome X ◽  
Control Group ◽  
Cardiac Syndrome X ◽  
Cross Sectional ◽  
Cardiac Syndrome ◽  
Stratification Method ◽  
The Mean

BACKGROUND Cardiac syndrome X (CSX) is not benign, and it needs long-term follow up and risk factor modification. In this study, we wanted to calculate microcirculatory transit time on coronary angiography in patients with cardiac syndrome X (CSX), compare microcirculatory transit time in patients with and without CSX and to see whether microcirculatory transit time can be proposed as a risk stratification method in CSX. METHODS Cross sectional study of 52 patients. The angiogram was taken at 15 frames per second. The left coronary artery was injected with 7 ml of contrast approximately. Microcirculatory transit time (MCTT) was obtained offline. The microcirculatory transit time in seconds is calculated as last frame count minus first frame count/15. Microcirculatory transit time was compared and analysed in both groups. RESULTS A total of 52 subjects were analysed. There were 26 cases in the angina group with a mean age of 49.96 years and 26 cases in the control group with a mean age of 50.32 years. Dyslipidemia, smoking and statin use were more common in the angina group, which was statistically significant (P < 0.05). The mean MCTT of the group with angina and positive treadmill test (TMT) was 6.76 seconds, whereas the negative TMT group was 6.39 seconds. The mean frame count was 58.1, and the mean MCTT was 3.8 seconds in the control group, whereas the mean frame count and mean MCTT were 98.1 and 6.5 seconds in the angina group, which was statistically significant (P < 0.001). CONCLUSIONS CSX patients had longer MCTT than patients without chest pain and normal coronary arteries. MCTT can be used to assess the risks of CSX. Long-term followup studies with a large sample size should be conducted. KEYWORDS Cardiac Syndrome X, Angina, Coronary Artery Disease, Microcirculation

Effect of Medialization of the Trochlear Groove and Lateralization of the Tibial Tubercle on TT-TG Distance: A Cross-sectional Study of Dysplastic and Nondysplastic Knees

2021 ◽  
pp. 036354652098781
Author(s):  
Mathias Paiva ◽  
Lars Blønd ◽  
Per Hölmich ◽  
Kristoffer Weisskirchner Barfod
Keyword(s):  
Trochlear Dysplasia ◽  
Cross Sectional Study ◽  
Magnetic Resonance Images ◽  
Tibial Tubercle ◽  
Control Group ◽  
Trochlear Groove ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mean Values ◽  
The Mean

Background: Tibial tubercle–trochlear groove (TT-TG) distance is often used as a measure of lateralization of the TT and is important for surgical planning. Purpose: To investigate if increased TT-TG distance measured on axial magnetic resonance images is due to lateralization of the TT or medialization of the TG. Study Design: Cross-sectional study; Level of evidence, 3. Methods: A total of 84 knees (28 normal [NK], 28 with trochlear dysplasia [TD], and 28 with patellar dislocation without TD [PD]) were examined. The medial border of the posterior cruciate ligament (PCL) was chosen as the central anatomic landmark. The distance from the TT to PCL (TT-PCL) was measured to examine the lateralization of the TT. The distance from the TG to the PCL (TG-PCL) was measured to examine the medialization of the TG. Between-group differences were investigated by use of 1-way analysis of variance. Results: The mean values for TT-TG distance were 8.7 ± 3.6 mm for NK, 12.1 ± 6.0 mm for PD, and 16.7 ± 4.3 mm in the TD group ( P < .01). The mean values for TT-PCL distance were 18.5 ± 3.6 mm for NK, 18.5 ± 4.5 mm for PD, and 21.2 ± 4.2 mm in the TD group ( P = .03). The mean values for TG-PCL distance were 9.6 ± 3.0 mm for NK, 7.1 ± 3.4 mm for PD, and 5.1 ± 3.3 mm in the dysplastic group ( P < .01). Conclusion: The present results indicate that increased TT-TG distance is due to medialization of the TG and not lateralization of the TT. Knees with TD had increased TT-TG distance compared with the knees of the control group and the knees with PD. The TT-PCL distance did not differ significantly between groups, whereas the TG-PCL distance declined with increased TT-TG.

Serum bilirubin predicts long-term clinical outcomes in patients with cardiac syndrome X

Heart ◽  
2010 ◽  
Vol 96 (15) ◽  
pp. 1227-1232 ◽  
Author(s):  
S.-S. Huang ◽  
P.-H. Huang ◽  
H.-B. Leu ◽  
T.-C. Wu ◽  
S.-J. Lin ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Serum Bilirubin ◽  
Syndrome X ◽  
Cardiac Syndrome X ◽  
Cardiac Syndrome

scholarly journals Long-term prognosis of patients with cardiac syndrome X: a review

2012 ◽  
Vol 20 (9) ◽  
pp. 365-371 ◽  
Author(s):  
I. A. C. Vermeltfoort ◽  
G. J. J. Teule ◽  
A. B. van Dijk ◽  
H. J. Muntinga ◽  
P. G. H. M. Raijmakers
Keyword(s):  
Syndrome X ◽  
Cardiac Syndrome X ◽  
Cardiac Syndrome ◽  
Long Term Prognosis

scholarly journals Association between endometriosis, headache, and migraine

2019 ◽  
Vol 11 (1) ◽  
pp. 19-24 ◽  
Author(s):  
Burcin Karamustafaoglu Balci ◽  
Zehra Kabakci ◽  
Damla Y Guzey ◽  
Bartu Avci ◽  
Murathan Guler ◽  
...  
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Medical Records ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Autonomic Nervous ◽  
Screening Questions ◽  
The Mean ◽  
Id Migraine

Introduction: Available data suggest that there is an association between endometriosis and a group of disorders including autonomic nervous system irregularities. A deeper understanding of relationship between endometriosis and autonomic nervous system is needed as it may lead to novel discoveries on the causes or consequences of endometriosis. In this study, we analyzed the prevalence of migraine in patients with endometriosis. Methods: In this cross-sectional study, medical records of women were reviewed through January 2013 to December 2017. Women with laparoscopically proven endometriosis (n = 185) were compared with those without endometriosis (n = 168). The 3-item screening questions (ID Migraine™) test was used to screen migraine. Data were analyzed using SPSS v25 (IBM Corporation). The χ2 test was used for analyzing the nominal parameters and group comparisons. Pearson χ2 was used to study the association between endometriosis and migraine. Results: The mean age was 31.86 ± 4.49 years of the endometriosis group and 28.95 ± 5.11 years of the controls (p = 0.408). The two pre-screening questions of ID Migraine test were answered positively by 86 patients of the endometriosis group (75.4%) and by 53 patients of the control group (54.6%) (p = 0.001). Of these patients, 51 (44.7% of endometriosis group) and 26 (26.8% of control group) were diagnosed as having migraine using 3-item Migraine questionnaire (p = 0.007). Conclusion: This study showed that the prevalence of migraine was significantly higher in patients with endometriosis. Because there is a strong correlation, patients with endometriosis should be screened for headache and migraine to increase the benefits of care.

scholarly journals Pattern ERG as a predictor in ocular hypertensive

2016 ◽  
Vol 15 (2) ◽  
Author(s):  
Paaraj Dave ◽  
Jitendra Jethani
Keyword(s):  
Amplitude Ratio ◽  
Corneal Thickness ◽  
Visual Fields ◽  
Cross Sectional Study ◽  
Control Group ◽  
Study Group ◽  
Pattern Erg ◽  
Check Size ◽  
Cross Sectional ◽  
The Mean

Purpose: To report the repeatability of Pattern Electrotretinogram (PERG) and its findings in ocular hypertension (OHT) and normal eyes.Methods: A cross-sectional study where PERG responses were compared between the study group comprising of 80 eyes of 80 patients with intraocular pressure (IOP)>21 mmHg and the control group with 80 eyes of 80 normal individuals (IOP≤21mmHg). The optic disc and the visual fields were normal with a visual acuity of ≥ 0.8 in both groups. PERG was recorded twice for each individual in the control group by a single operator on 2 consecutive days to assess the repeatability.Results: The mean age in the study and control groups was 50.05±10.03 and 54.8±7.66 years(p=0.44) respectively. The mean IOP was 26.55±3.9 mmHg for the study group as opposed to 14.45±2.9 mmHg for the controls (p<0.001). The central corneal thickness and the cup-disc ratio was similar between the groups (p>.05). The P50-N95 amplitude (p=0.01) and the P50 latency (p<0.001) was statistically significantly different between both the groups. The intra-class correlation coefficient (ICC) showed poor agreement for all parameters except for N35-P50 0.8 to 16 degree check size amplitude ratio (PERG ratio).Conclusion:  Increase in P50 latency emerges as a new candidate for early glaucoma indicator in addition to reduction in P50-N95 amplitude. PERG parameters suffer from high test-retest variability. Deterioration in PERG recordings should be interpreted with caution. The variability is lesser for the PERG ratio which maybe more meaningful while monitoring for change over time.

scholarly journals Evaluation of the coronary flow by the coronary clearance time in patients with cardiac syndrome X

2017 ◽  
Vol 46 (3) ◽  
pp. 1121-1129 ◽  
Author(s):  
Erkan Yildirim ◽  
Uygar Cagdas Yuksel ◽  
Murat Celik ◽  
Baris Bugan ◽  
Mutlu Gungor ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Nuclear Imaging ◽  
Microvascular Dysfunction ◽  
Syndrome X ◽  
Control Group ◽  
Coronary Microvascular Dysfunction ◽  
Cardiac Syndrome X ◽  
Conventional Angiography ◽  
Cardiac Syndrome ◽  
Normal Coronary Angiography

Objective The vessels involved in the microcirculation are too small to be visualized by conventional angiography and no tools are currently available that can directly evaluate the coronary microcirculation. This study evaluated the coronary clearance frame count (CCFC) in patients with cardiac syndrome X (CSX). Methods The retrospective study enrolled patients with angina, who had a positive nuclear imaging test and normal coronary angiography; and a control group consisting of patients who underwent an angiogram to exclude coronary artery disease. Thrombosis in myocardial infarction frame count (TFC) and CCFC for each coronary artery (left anterior descending coronary artery [LAD], circumflex coronary artery [CFX] and right coronary artery [RCA]) were calculated offline. Results A total of 71 patients with CSX and 61 control patients were enrolled in the study. No significant differences were found between the two groups regarding the baseline demographic and clinical variables. The TFC of LAD, CFX and RCA were similar between the two groups. The mean CCFC-LAD, CCFC-CFX and CCFC-RCA were significantly longer in the CSX group compared with the control group. Conclusion CCFC is a simple, quantitative and highly reproducible method that might be used as a marker of coronary microvascular dysfunction.

Long-term prognosis of patients with cardiac syndrome X

2010 ◽  
Vol 140 (2) ◽  
pp. 197-199 ◽  
Author(s):  
Priscilla Lamendola ◽  
Gaetano A. Lanza ◽  
Antonella Spinelli ◽  
Gregory A. Sgueglia ◽  
Antonio Di Monaco ◽  
...  
Keyword(s):  
Syndrome X ◽  
Cardiac Syndrome X ◽  
Cardiac Syndrome ◽  
Long Term Prognosis

scholarly journals Sense of coherence and its associations with psychosocial health: results of survey of the unemployed in Kaunas

Medicina ◽  
2009 ◽  
Vol 45 (10) ◽  
pp. 807 ◽  
Author(s):  
Mindaugas Stankūnas ◽  
Ramunė Kalėdienė ◽  
Skirmantė Starkuvienė
Keyword(s):  
Sense Of Coherence ◽  
Adult Population ◽  
Psychosocial Health ◽  
Cross Sectional Study ◽  
Life Questionnaire ◽  
Cross Sectional ◽  
Reported Health ◽  
The Mean ◽  
The Unemployed

Objective. To evaluate the associations between sense of coherence and psychosocial health among unemployed adult population. Material and methods. The data were collected during a cross-sectional study in 2005. There were 429 filled-in questionnaires received (response rate, 53.6%) from unemployed persons registered at the Kaunas Labor Market Office (Lithuania). For the assessment of the sense of coherence, a short 13-item version of the Orientation to Life Questionnaire was used. Long-term unemployment was defined as lasting 12 months or longer. Logistic regression was used to estimate the risk factors having influence on sense of coherence. The risk was evaluated using odds ratio (OR). Results. The mean score for sense of coherence was 56.6±11.2 (min, 13; max, 91). Significantly higher sense of coherence was found among the short-term unemployed as compare to the long-term ones. Analysis showed that sense of coherence was significantly higher in males, more educated and less materially deprived groups. The findings indicated that persons with depression, suicide intentions, more intensive alcohol consumption (after the job loss), poor self-reported health, feelings of loneliness and shame, and poor relations with family reported lower sense of coherence. The risk of low sense of coherence was significantly higher for females (OR=2.97) and the long-term unemployed (OR=1.81). Nevertheless, higher education (OR=0.73) and income (OR=0.83) were the factors that significantly improved sense of coherence. Conclusions. Sense of coherence was low among the unemployed in Kaunas. Sense of coherence was lower among the unemployed with negative psychosocial health characteristics in comparison to the unemployed with positive characteristics.

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