scholarly journals Relapse of Sulfasalazine-induced DRESS Syndrome Following the Administration of Contrast Media: A Case Report

2021 ◽  
Author(s):  
Niayesh Mohebbi ◽  
Hamidreza Taghvaye Masoumi ◽  
Malihe Khosravi Khezri ◽  
Mona Talaschian
Keyword(s):  
Drug Reaction ◽  
Case Report ◽  
Contrast Media ◽  
Acute Exacerbation ◽  
Hypersensitivity Reactions ◽  
Iodinated Contrast Media ◽  
Dress Syndrome ◽  
Iodinated Contrast ◽  
Systemic Symptoms ◽  
High Possibility

Sulfasalazine, a non-antibiotic sulfonamide, is associated with severe hypersensitivity reactions, including Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome. We report a case of sulfasalazine-induced DRESS syndrome that relapsed following the administration of visipaque® (iodixanol). Macular rashes, pruritus, and an acute exacerbation of dyspnea were immediately observed after the administration of contrast media. It seems that patients suffering from DRESS syndrome are sensitive to the administration of other new medications with a high possibility of hypersensitive reactions. It can be concluded that iodinated contrast media should be used cautiously in patients with DRESS syndrome.

scholarly journals Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome induced by ceftriaxone with successful treatment — A case report and literature review

2022 ◽  
Vol 8 (4) ◽  
pp. 298-300
Author(s):  
Arpit Agrawal ◽  
Pankaj Kannauje
Keyword(s):  
Drug Reaction ◽  
Case Report ◽  
Literature Review ◽  
Sore Throat ◽  
Hypersensitivity Reactions ◽  
Dress Syndrome ◽  
Threatening Condition ◽  
Life Threatening ◽  
Systemic Symptoms ◽  
Prolonged Latency

Drug reaction with eosinophilia and systemic symptoms is a rare and potentially life threatening condition characterised by hypersensitivity reactions to a drug with prolonged latency, in the form of skin rashes, hyper eosinophilia and systemic features like fever, lymphadenopathy, leucocytosis, internal organ involvement (liver, kidney, lung). Though it can occur in response to many drugs but very few cases has been described in relation to one of the most commonly used antibiotic ceftriaxone. Here we have described a case of DRESS in a patient who has been treated with ceftriaxone outside our hospital for sore throat.

scholarly journals Pharmacologic and non-pharmacologic interventions to prevent hypersensitivity reactions of non-ionic iodinated contrast media: a systematic review protocol

BMJ Open ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. e033023
Author(s):  
Hiroyasu Umakoshi ◽  
Takashi Nihashi ◽  
Hironori Shimamoto ◽  
Takehiro Yamada ◽  
Hiroaki Ishiguchi ◽  
...  
Keyword(s):  
Contrast Media ◽  
Assessment Tools ◽  
Average Risk ◽  
Cochrane Central Register ◽  
Hypersensitivity Reactions ◽  
Iodinated Contrast Media ◽  
Preventive Interventions ◽  
Validity Assessment ◽  
Iodinated Contrast ◽  
Standard Design

IntroductionIodinated contrast media are commonly used in medical imaging and can cause hypersensitivity reactions, including rare but severe life-threatening reactions. Although several prophylactic approaches have been proposed for severe reactions, their effects remain unclear. Therefore, we aim to review systematically the preventive effects of pharmacologic and non-pharmacologic interventions and predictors of acute, hypersensitivity reactions.Methods and analysisWe will search the PubMed, EMBASE and Cochrane Central Register of Controlled Trials databases from 1 January 1990 through 31 December 2019 and will examine the bibliographies of eligible studies, pertinent review articles and clinical practice guidelines. We will include prospective and retrospective studies of any design that evaluated the effects of pharmacological and non-pharmacological preventive interventions for adverse reactions of non-ionic iodinated contrast media. Two assessors will independently extract the characteristics of the study and intervention and the quantitative results. Two independent reviewers will assess the risk of bias using standard design-specific validity assessment tools. The primary outcome will be reduction in acute contrast media-induced hypersensitivity reactions. The secondary outcomes will include characteristics associated with the development of contrast media-induced acute hypersensitivity reactions, and adverse events associated with specific preventive interventions. Unique premedication regimens (eg, dose, drug and duration) and non-pharmacological strategies will be analysed separately. Average-risk and high-risk patients will be considered separately. A meta-analysis will be performed if appropriate.Ethics and disseminationEthics approval is not applicable, as this will be a secondary analysis of publicly available data. The results of the analysis will be submitted for publication in a peer reviewed journal.PROSPERO registration numberCRD42019134003

scholarly journals Severe hypersensitivity reactions to iodinated contrast media: clinical and immunological features in a cohort of patients

2014 ◽  
Vol 4 (S3) ◽  
Author(s):  
Daniela Rivero Paparoni ◽  
Ana Fiandor ◽  
Rosario Cabañas ◽  
Hoi Yan-Tong ◽  
Elena Ramirez ◽  
...  
Keyword(s):  
Contrast Media ◽  
Hypersensitivity Reactions ◽  
Iodinated Contrast Media ◽  
Iodinated Contrast

scholarly journals Hypersensitivity Reactions to Iodinated Contrast Media.

2015 ◽  
Vol 10 (11-12) ◽  
pp. 269-273
Author(s):  
Zeljko Plazonic ◽  
Tanja Batinac ◽  
Marija Bukvic
Keyword(s):  
Contrast Media ◽  
Hypersensitivity Reactions ◽  
Iodinated Contrast Media ◽  
Iodinated Contrast

scholarly journals Drug reaction with eosinophilia and systemic symptoms (DRESS syndrome)

2016 ◽  
Vol 62 (3) ◽  
pp. 227-230 ◽  
Author(s):  
Soraia Aparecida da Silva ◽  
Mariana Maciel Pereira de Figueiredo ◽  
Lauro Carneiro Neto ◽  
Débora Borowiak Reiss ◽  
Mariana Amaranto de Souza Damásio
Keyword(s):  
Drug Reaction ◽  
Case Report ◽  
Literature Review ◽  
Hypersensitivity Reaction ◽  
Laboratory Tests ◽  
Immune Status ◽  
Target Organ ◽  
Dress Syndrome ◽  
Risk Of Mortality ◽  
Systemic Symptoms

SUMMARY Objective: To review the hypersensitivity reaction to drugs known as drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), based on a case report. We also intend to discuss the difficulty and importance of disease recognition, since none of the changes is pathognomonic of this disease and failure to identify it may have disastrous consequences for the patient. Method: To describe this case report, in addition to the information collected for clinical assessment, a literature review was performed in the PubMed and Bireme databases in order to retrieve the latest information published in literature on DRESS syndrome. Results: The case of a 20-year old patient is reported. After anamnesis, physical examination and laboratory tests a diagnosis of DRESS syndrome was performed, characterized by rash, hematologic alterations, lymphadenopathy and lesions in target organ. This is a rare syndrome, whose frequency varies according to the drug used and the immune status of the patient, being more often associated with the use of anticonvulsants. Conclusion: The approach and discussion of the topic are of paramount importance, in view of the potential lethality of this treatable syndrome. Recognizing the occurrence of DRESS syndrome and starting treatment as soon as possible is crucial to reduce the risk of mortality and improve prognosis.

Why Reporting The Iodinated Contrast Media Used During Radiological Procedures Should Be Standard Practice: A Case Report

2016 ◽  
Vol 38 (10) ◽  
pp. e31
Author(s):  
D. Juricic Nahal ◽  
I. Cegec ◽  
V. Erdeljic Turk ◽  
M. Radacic Aumiler ◽  
K. Makar Ausperger ◽  
...  
Keyword(s):  
Case Report ◽  
Contrast Media ◽  
Iodinated Contrast Media ◽  
Standard Practice ◽  
Iodinated Contrast ◽  
Radiological Procedures
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