scholarly journals Evaluation of Serum Gonadotropin and Prolactin Level among Sudanese Patients with Chronic Renal Failure

2021 ◽  
Author(s):  
Maha Fathalla ◽  
AbdElkarim A. Abdrabo ◽  
GadAllah Modawe
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Case Control Study ◽  
Case Control ◽  
Serum Prolactin ◽  
P Value ◽  
Serum Hormones ◽  
Serum Gonadotropin ◽  
Plasma Hormones ◽  
Control Study

Background: Generally, patients on hemodialysis for chronic renal failure also have endocrine defects and sexual function disorders. In this study, we aimed to assess the serum prolactin (PRL), luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in patients with chronic renal failure. Methods: This hospital-based case–control study was conducted at Jabal Aulia Teaching Hospital, Khartoum, Sudan. The study was carried out between August 2019 and February 2020. A total of 100 subjects were enrolled – 50 chronic renal failure patients and 50 as controls. The serum hormones were estimated using Tosoh 360. SPSS version 25 was used to analyze the results. Results: The serum PRL, LH, and FSH were significantly increased among chronic renal failure patients than their healthy counterparts (p-value = 0.000). The age of patients was positive correlated with plasma hormones, PRL (r = 0.332, p = 0.001), LH (r = 0.387, p = 0.000), and FSH (r = 0.320, p = 0.001). No correlation was found between the duration of the disease and serum hormones. Conclusion: Patients with chronic renal failure had a highly significant increase of serum PRL, LH, and FSH and also the age of the patients was positively correlated with serum hormones. Keywords: chronic renal failure, prolactin, gonadotropin, hemodialysis

SERUM PROLACTINE LEVEL IN PATIENTS OF PSORIASIS VULGARIS AND ITS CORRELATION WITH DISEASE SEVERITY: A CASE-CONTROL STUDY

2019 ◽  
Vol 3 (6) ◽  
Author(s):  
Pawan Kumar Saini ◽  
Devendra Yadav ◽  
Rozy Badyal ◽  
Suresh Jain ◽  
Arti Singh ◽  
...  
Keyword(s):  
Disease Severity ◽  
Prolactin Level ◽  
Case Control Study ◽  
Statistical Significance ◽  
Case Control ◽  
Serum Prolactin ◽  
P Value ◽  
Serum Prolactin Level ◽  
R Value ◽  
Control Study

Background: Psoriasis is an autoimmune chronic inflammatory disorder affecting the skin mediated by T-lymphocytes resulting in production of cytokines which cause hyperproliferation of keratinocytes.  Several factors and hormones like Prolactin have an action similar to these cytokines in promoting the multiplication of keratinocytes and other cells like lymphocytes and epithelial cells may have a role on the etiopathogenesis of psoriasis. Aim:-The aim of study is to compare the serum Prolactin levels in patients of psoriasis with a control group. Setting and study design: This is a case-control study conducted in the department of Dermatology, Venereology and Leprosy GMC, Kota over a period of 1year from July 2017 to June 2018 Material and method: The study included 100 cases of psoriasis (60 males and 40 females) and 100 controls similar for age and sex. Serum Prolactin levels were measured by ECLIA and results were obtained. Statistical analysis: Mean and standard deviation were calculated for each variable. Statistical significance of the results was analyzed using correlation analysis (Pearson correlation coefficient) and independent samples t-test. Statistical significance was assumed at p value<0.05. Result: Serum Prolactin level was significantly higher in cases of psoriasis compared to controls (p-value <0.001). PASI score and serum Prolactin levels were found to have a positive correlation (r value = 0.337; p-value: 0.001). No significant  correlation was found between serum levels of Prolactin and duration of disease r value= -0.034, P value =0.733). Serum Prolactin level was higher in male patients compared to females patients. Conclusion:- High serum Prolactin may be a biological marker of disease severity in psoriasis and may have a role in the pathogenesis of psoriasis. Further studies with large sample size are required to confirm this hypothesis.

scholarly journals Evaluation of oxidative stress biomarkers in patients with chronic renal failure: a case control study

2010 ◽  
Vol 3 (1) ◽  
pp. 20 ◽  
Author(s):  
Marta Romeu ◽  
Rosa Nogues ◽  
Luís Marcas ◽  
Vanesa Sánchez-Martos ◽  
Miquel Mulero ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Case Control Study ◽  
Case Control ◽  
Oxidative Stress Biomarkers ◽  
Stress Biomarkers ◽  
Control Study

A case-control study on the affective temperament profiles, anxiety and depression levels of patients with chronic renal failure

2016 ◽  
Vol 6 (3) ◽  
pp. 133
Author(s):  
Ebru Findikli ◽  
Mehmet Camkurt ◽  
Filiz Izci ◽  
Yasemin Yavuz ◽  
Huseyin Findikli ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Case Control Study ◽  
Case Control ◽  
Anxiety And Depression ◽  
Affective Temperament ◽  
Control Study

scholarly journals Prevalence of Intestinal Protozoa among Saudi Patients with Chronic Renal Failure: A Case-Control Study

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Yousry A. Hawash ◽  
Laila Sh. Dorgham ◽  
El-Amir M. Amir ◽  
Osama F. Sharaf
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Case Control Study ◽  
Clinical Symptoms ◽  
Giardia Duodenalis ◽  
Case Control ◽  
Intestinal Protozoa ◽  
Stool Samples ◽  
Matched Case ◽  
Control Study

It has been hypothesized that chronic renal failure (CRF) predisposes patients to infection with intestinal protozoa. We tested this hypothesis with a matched case-control study to determine the prevalence of these protozoa and their diarrhea associated symptoms among 50 patients with CRF (cases) from Taif, western Saudi Arabia. Fifty diarrheal patients without CRF were recruited in the study as controls. Participants were interviewed by a structured questionnaire and stool samples were collected. Samples were thoroughly examined with microscopy and three coproantigens detection kits. Enteric protozoa were detected in 21 cases and 14 controls.Blastocystisspp. were the most predominant parasite (16% in cases versus 8% in controls), followed byGiardia duodenalis(10% in cases versus 12% in controls) andCryptosporidiumspp. (10% in cases versus 6% in controls).Cyclospora cayetanensiswas identified in two cases, whileEntamoeba histolyticawas described in one case and one control. Intestinal parasitism was positively associated with the male gender, urban residence, and travel history. Clinical symptoms of nausea/vomiting and abdominal pain were significantly varied between the parasitized cases and controls (Pvalue≤0.05). Given the results, we recommend screening all diarrheal feces for intestinal protozoa in the study’s population, particularly those with CRF.

Factors associated with chronic renal failure in 121 patients with diffuse proliferative lupus nephritis: a case-control study

Lupus ◽  
1995 ◽  
Vol 4 (3) ◽  
pp. 197-203 ◽  
Author(s):  
C.A. Arce-Salinas ◽  
A.R. Villa ◽  
J.O. Martínez-Rueda ◽  
L. Muñoz ◽  
M.H. Cardiel ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Lupus Nephritis ◽  
Case Control Study ◽  
Case Control ◽  
Factors Associated ◽  
Proliferative Lupus Nephritis ◽  
Control Study

A case-control study on restless legs syndrome in nondialyzed patients with chronic renal failure

2010 ◽  
Vol 25 (8) ◽  
pp. 1019-1025 ◽  
Author(s):  
Giovanni Merlino ◽  
Simone Lorenzut ◽  
Gian Luigi Gigli ◽  
Giulio Romano ◽  
Domenico Montanaro ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Restless Legs Syndrome ◽  
Case Control Study ◽  
Case Control ◽  
Restless Legs ◽  
Control Study
Sign in / Sign up

Export Citation Format

Share Document