scholarly journals Spectrum of Disorders Diagnosed By Bone Marrow Aspiration in Pediatric Population

2015 ◽  
Author(s):  
Dr Aparajita Tomar ◽  
◽  
Dr RPS Chauhan ◽  
Dr R.K Nigam
Keyword(s):  
Bone Marrow ◽  
Pediatric Population ◽  
Bone Marrow Aspiration

scholarly journals A Case of COVID-19-Related Thrombocytopenia and Leukopenia in an Adolescent with Mild Symptoms

Children ◽  
2021 ◽  
Vol 8 (6) ◽  
pp. 509
Author(s):  
Lydia Kossiva ◽  
Athanasios Thirios ◽  
Eleni Panagouli ◽  
Alexandros Panos ◽  
Stavroula Lampidi ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Viral Infection ◽  
Nasal Congestion ◽  
Pediatric Population ◽  
Clinical Manifestations ◽  
Bone Marrow Aspiration ◽  
White Blood Count ◽  
Chronic Obstructive ◽  
First Case ◽  
The Impact

Since the beginning of the COVID-19 pandemic, there have been numerous reports and reviews on the complications caused by the disease, analyzing the acute and chronic consequences. The main symptoms of SARS-CoV-2 are dry cough, fever, and fatigue. COVID-19 appears to affect all systems, including renal, cardiovascular, circulatory, and respiratory systems, causing chronic obstructive pulmonary disease. We report on a 14-year-old male adolescent, who presented with thrombocytopenia (platelet count 92 × 109 /L) and leukopenia (white blood count 4.2 × 103 /μL) that was observed two months ago. Ten days before the first blood test, a viral infection with nasal congestion and runny nose was reported, without other accompanying symptoms. Viral antibodies screening revealed positivity for all the three specific COVID-19 antibodies. Further haematological evaluation with bone marrow aspiration revealed non-specific dysplastic features of the red cell and megakaryocyte progenitors. Although haematological alterations due to COVID-19 infection are available from adult patients’ reports, the effect of COVID-19 infection in the pediatric population is underestimated and this is the first case with such haematological involvement. Noteworthy, in the current case, the impact of the COVID-19 infection was not related to the severity of the disease, as the symptoms were mild. In similar cases, bone marrow aspiration would not be performed as a part of routine work-up. Thus, it is important when evaluating pediatric patients with COVID-19 infection to search and report those alterations in order to better understand the impact and the spectrum of clinical manifestations of the specific viral infection in children and adolescents.

scholarly journals A RETROSPECTIVE CROSS SECTIONAL STUDY ON PATTERN & DISTRIBUTION OF PEDIATRIC HEMATOLOGICAL MALIGNANCIES IN CENTRAL PART OF INDIA

2020 ◽  
pp. 1-3
Author(s):  
Bimla Banjare ◽  
Amit Kumar Bhardwaj ◽  
Riti Sharma
Keyword(s):  
Bone Marrow ◽  
Hematological Malignancies ◽  
Pediatric Population ◽  
Age Groups ◽  
Bone Marrow Aspiration ◽  
Developed Countries ◽  
Age Group ◽  
Cross Sectional ◽  
Acute Leukemias ◽  
Female Ratio

Hematological Malignancies (HMs) consists of a diverse group of neoplastic diseases involving Bone Marrow, Lymph nodes or other Secondary Immune Organs. Conventionally, HMs represents 2 major group of diseases – Leukemia & Lymphoma. All Hematological Malignancies are on the rise as compared to few decades back worldwide but, it’s major brunt is faced by the under developed countries of the world. A retrospective study in a Government Teaching Hospital was undertaken to characterize Pattern and Distribution of HMs in children in Chhattisgarh state of India. A total number of 65 Bone Marrow Aspiration Cytology cases were evaluated from 1st January 2019 to 31st December 2019 for a period of 1 year. Pediatric Population was categorized into 3 age groups – 0-2 years, 2-12 years and 12-16 years. Male to Female ratio was 2.4:1 in our study with most cases being of Acute Leukemias (95.4%). On further evaluation, ALL had highest numbers with 37 cases (57.0 %) followed by Acute Leukemia and AML with 14 (21.52%) & 10 (15.38%) cases respectively. The highest number of cases were seen in 2-12 years age group (n=49, 75.4%) implying that children of such age group presenting with signs and symptoms of HMs must be thoroughly evaluated for early diagnosis and treatment.

Vitamin B12 Deficiency an Unusual Cause of Fever: A Case Report

2019 ◽  
Vol 4 (02) ◽  
Author(s):  
Shyama . ◽  
P. Kumar ◽  
Surabhi .
Keyword(s):  
Bone Marrow ◽  
Vitamin B12 ◽  
Unusual Case ◽  
Vitamin B12 Deficiency ◽  
Bone Marrow Aspiration ◽  
Microcytic Anemia ◽  
Peripheral Smear ◽  
Erythroid Hyperplasia ◽  
B12 Deficiency ◽  
Vitamin B12 Supplementation

Introduction: An unusual case of a 19 year old female, presenting with fever, pallor and hepatosplenomegaly for one month. She had microcytic anemia on peripheral smear examination but her bone marrow aspiration & biopsy revealed a hypercelluar marrow with megaloblastic erythroid hyperplasia. Resolution of fever within 48 hours of Vitamin B12 supplementation, initiated in view of the megaloblastic bone marrow picture & low serumVitamin B12 level, suggests a causal association. Conclusion: Vitamin B12 deficiency seems to be an unusual cause of PUO (Pyrexia of unkown origin) which should be ruled out in every case of PUO.

Understanding bone safety zones during bone marrow aspiration from the iliac crest: the sector rule

2014 ◽  
Vol 38 (11) ◽  
pp. 2377-2384 ◽  
Author(s):  
Jacques Hernigou ◽  
Laure Picard ◽  
Alexandra Alves ◽  
Jonathan Silvera ◽  
Yasuhiro Homma ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Iliac Crest ◽  
Bone Marrow Aspiration

scholarly journals Evaluation of qPCR on blood and skin microbiopsies, peripheral blood buffy coat smear, and urine antigen ELISA for diagnosis and test of cure for visceral leishmaniasis in HIV-coinfected patients in India: a prospective cohort study

BMJ Open ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. e042519
Author(s):  
Sophie I Owen ◽  
Sakib Burza ◽  
Shiril Kumar ◽  
Neena Verma ◽  
Raman Mahajan ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Visceral Leishmaniasis ◽  
Hiv Infection ◽  
Peripheral Blood ◽  
Medical Science ◽  
Bone Marrow Aspiration ◽  
Buffy Coat ◽  
Tropical Medicine ◽  
Urine Antigen ◽  
Antigen Elisa

IntroductionHIV coinfection presents a challenge for diagnosis of visceral leishmaniasis (VL). Invasive splenic or bone marrow aspiration with microscopic visualisation of Leishmania parasites remains the gold standard for diagnosis of VL in HIV-coinfected patients. Furthermore, a test of cure by splenic or bone marrow aspiration is required as patients with VL-HIV infection are at a high risk of treatment failure. However, there remain financial, implementation and safety costs to these invasive techniques which severely limit their use under field conditions.Methods and analysisWe aim to evaluate blood and skin qPCR, peripheral blood buffy coat smear microscopy and urine antigen ELISA as non-invasive or minimally invasive alternatives for diagnosis and post-treatment test of cure for VL in HIV-coinfected patients in India, using a sample of 91 patients with parasitologically confirmed symptomatic VL-HIV infection.Ethics and disseminationEthical approval for this study has been granted by The Liverpool School of Tropical Medicine, The Institute of Tropical Medicine in Antwerp, the University of Antwerp and the Rajendra Memorial Research Institute of Medical Science in Patna. Any future publications will be published in open access journals.Trial registration numberCTRI/2019/03/017908.

scholarly journals A Novel Approach for Performing Bone Marrow Aspiration at the Time of Radical Prostatectomy

2016 ◽  
Vol 6 ◽  
pp. 45-46
Author(s):  
Jeffrey J. Tosoian ◽  
Diane K. Reyes ◽  
Michael A. Gorin ◽  
Steven Hortopan ◽  
Alan W. Partin ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Radical Prostatectomy ◽  
Bone Marrow Aspiration ◽  
Novel Approach

scholarly journals What should I know before ordering a bone marrow aspiration/biopsy in patients with vitamin B12 deficiency?

2013 ◽  
Vol 2013 (jul08 1) ◽  
pp. bcr2013010200-bcr2013010200 ◽  
Author(s):  
J. Randhawa ◽  
S. L. Ondrejka ◽  
S. Setrakian ◽  
H. Taylor
Keyword(s):  
Bone Marrow ◽  
Vitamin B12 ◽  
Vitamin B12 Deficiency ◽  
Bone Marrow Aspiration ◽  
Aspiration Biopsy ◽  
B12 Deficiency
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